Modeling of Microscale Transport in Biological Processes


Book Description

Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels. - Features recent developments in theoretical and computational modeling for clinical researchers and engineers - Furthers researcher understanding of fluid flow in biological media and focuses on biofluidics at the microscale - Includes chapters expertly authored by internationally recognized authorities in the fundamental and applied fields that are associated with microscale transport in living media




Transport in Biological Media


Book Description

Transport in Biological Media is a solid resource of mathematical models for researchers across a broad range of scientific and engineering problems such as the effects of drug delivery, chemotherapy, or insulin intake to interpret transport experiments in areas of cutting edge biological research. A wide range of emerging theoretical and experimental mathematical methodologies are offered by biological topic to appeal to individual researchers to assist them in solving problems in their specific area of research. Researchers in biology, biophysics, biomathematics, chemistry, engineers and clinical fields specific to transport modeling will find this resource indispensible. - Provides detailed mathematical model development to interpret experiments and provides current modeling practices - Provides a wide range of biological and clinical applications - Includes physiological descriptions of models




Heat Transfer and Fluid Flow in Biological Processes


Book Description

Heat Transfer and Fluid Flow in Biological Processes covers emerging areas in fluid flow and heat transfer relevant to biosystems and medical technology. This book uses an interdisciplinary approach to provide a comprehensive prospective on biofluid mechanics and heat transfer advances and includes reviews of the most recent methods in modeling of flows in biological media, such as CFD. Written by internationally recognized researchers in the field, each chapter provides a strong introductory section that is useful to both readers currently in the field and readers interested in learning more about these areas. Heat Transfer and Fluid Flow in Biological Processes is an indispensable reference for professors, graduate students, professionals, and clinical researchers in the fields of biology, biomedical engineering, chemistry and medicine working on applications of fluid flow, heat transfer, and transport phenomena in biomedical technology. - Provides a wide range of biological and clinical applications of fluid flow and heat transfer in biomedical technology - Covers topics such as electrokinetic transport, electroporation of cells and tissue dialysis, inert solute transport (insulin), thermal ablation of cancerous tissue, respiratory therapies, and associated medical technologies - Reviews the most recent advances in modeling techniques




Transport Processes at Fluidic Interfaces


Book Description

There are several physico-chemical processes that determine the behavior of multiphase fluid systems – e.g., the fluid dynamics in the different phases and the dynamics of the interface(s), mass transport between the fluids, adsorption effects at the interface, and transport of surfactants on the interface – and result in heterogeneous interface properties. In general, these processes are strongly coupled and local properties of the interface play a crucial role. A thorough understanding of the behavior of such complex flow problems must be based on physically sound mathematical models, which especially account for the local processes at the interface. This book presents recent findings on the rigorous derivation and mathematical analysis of such models and on the development of numerical methods for direct numerical simulations. Validation results are based on specifically designed experiments using high-resolution experimental techniques. A special feature of this book is its focus on an interdisciplinary research approach combining Applied Analysis, Numerical Mathematics, Interface Physics and Chemistry, as well as relevant research areas in the Engineering Sciences. The contributions originated from the joint interdisciplinary research projects in the DFG Priority Programme SPP 1506 “Transport Processes at Fluidic Interfaces.”




Advances in Heat Transfer


Book Description

Advances in Heat Transfer, Volume 52, provides in-depth review articles from a broader scope than in traditional journals or texts, with this comprehensive release covering chapters on Thermal Convection Studies at the University of Minnesota, Convective heat transfer in porous passages that depends on the values of the Sparrow numbers, Automatic Code Differentiation for Thermal-Fluid Problems, Advances in Vapor Chambers and Phase Change Heat Spreaders, Pressure Drop and Heat Transfer in the Entrance Region of Microchannels, Predicting spectral thermal conductivity at the mesoscale with advanced deterministic phonon transport techniques, and Modulated-heating protocols applied to hyperthermia/thermal ablation. Fills the information gap between regularly scheduled journals and university-level textbooks by providing in-depth review articles over a broader scope than in traditional journals or texts Provides essential reading for all mechanical, chemical and industrial engineers working in the field of heat transfer Presents a great resource for use in graduate school level courses




Microbiome Under Changing Climate


Book Description

Microbiome Under Changing Climate: Implications and Solutions presents the latest biotechnological interventions for the judicious use of microbes to ensure optimal agricultural yield. Summarizing aspects of vulnerability, adaptation and amelioration of climate impact, this book provides an important resource for understanding microbes, plants and soil in pursuit of sustainable agriculture and improved food security. It emphasizes the interaction between climate and soil microbes and their potential role in promoting advanced sustainable agricultural solutions, focusing on current research designed to use beneficial microbes such as plant growth promoting microorganisms, fungi, endophytic microbes, and more. Changes in climatic conditions influence all factors of the agricultural ecosystem, including adversely impacting yield both in terms of quantity and nutritional quality. In order to develop resilience against climatic changes, it is increasingly important to understand the effect on the native micro-flora, including the distribution of methanogens and methanotrophs, nutrient content and microbial biomass, among others. - Demonstrates the impact of climate change on secondary metabolites of plants and potential responses - Incorporates insights on microflora of inhabitant soil - Explores mitigation processes and their modulation by sustainable methods - Highlights the role of microbial technologies in agricultural sustainability




Nano and Bio Heat Transfer and Fluid Flow


Book Description

Nano and Bio Heat Transfer and Fluid Flow focuses on the use of nanoparticles for bio application and bio-fluidics from an engineering perspective. It introduces the mechanisms underlying thermal and fluid interaction of nanoparticles with biological systems. This book will help readers translate theory into real world applications, such as drug delivery and lab-on-a-chip. The content covers how transport at the nano-scale differs from the macro-scale, also discussing what complications can arise in a biologic system at the nano-scale. It is ideal for students and early career researchers, engineers conducting experimental work on relevant applications, or those who develop computer models to investigate/design these systems. Content coverage includes biofluid mechanics, transport phenomena, micro/nano fluid flows, and heat transfer. - Discusses nanoparticle applications in drug delivery - Covers the engineering fundamentals of bio heat transfer and fluid flow - Explains how to simulate, analyze, and evaluate the transportation of heat and mass problems in bio-systems




Advances in Transport Phenomena


Book Description

The term transport phenomena is used to describe processes in which mass, momentum, energy and entropy move about in matter. Advances in Transport Phenomena provide state-of-the-art expositions of major advances by theoretical, numerical and experimental studies from a molecular, microscopic, mesoscopic, macroscopic or megascopic point of view across the spectrum of transport phenomena, from scientific enquiries to practical applications. The annual review series intends to fill the information gap between regularly published journals and university-level textbooks by providing in-depth review articles over a broader scope than in journals. The authoritative articles, contributed by internationally-leading scientists and practitioners, establish the state of the art, disseminate the latest research discoveries, serve as a central source of reference for fundamentals and applications of transport phenomena, and provide potential textbooks to senior undergraduate and graduate students. This review book provides state-of-the-art expositions of major advances by theoretical, numerical and experimental studies from a molecular, microscopic, mesoscopic, macroscopic or megascopic point of view across the spectrum of transport phenomena, from scientific enquiries to practical applications. This new volume of the annual review "Advances in Transport Phenomena" series provides in-depth review articles covering the fields of mass transfer, fluid mechanics, heat transfer and thermodynamics. This review book provides state-of-the-art expositions of major advances by theoretical, numerical and experimental studies from a molecular, microscopic, mesoscopic, macroscopic or megascopic point of view across the spectrum of transport phenomena, from scientific enquiries to practical applications. This new volume of the annual review "Advances in Transport Phenomena" series provides in-depth review articles covering the fields of mass transfer, fluid mechanics, heat transfer and thermodynamics.




Dynamic Process Modeling


Book Description

Inspired by the leading authority in the field, the Centre for Process Systems Engineering at Imperial College London, this book includes theoretical developments, algorithms, methodologies and tools in process systems engineering and applications from the chemical, energy, molecular, biomedical and other areas. It spans a whole range of length scales seen in manufacturing industries, from molecular and nanoscale phenomena to enterprise-wide optimization and control. As such, this will appeal to a broad readership, since the topic applies not only to all technical processes but also due to the interdisciplinary expertise required to solve the challenge. The ultimate reference work for years to come.




Additive Manufacturing


Book Description

Additive Manufacturing explains the background theory, working principles, technical specifications, and latest developments in a wide range of additive manufacturing techniques. Topics addressed include treatments of manufactured parts, surface characterization, and the effects of surface treatments on mechanical behavior. Many different perspectives are covered, including design aspects, technologies, materials and sustainability. Experts in both academia and industry contribute to this comprehensive guide, combining theoretical developments with practical improvements from R&D. This unique guide allows readers to compare the characteristics of different processes, understand how they work, and provide parameters for their effective implementation. This book is part of a four-volume set entitled Handbooks in Advanced Manufacturing. Other titles in the set include Advanced Machining and Finishing, Advanced Welding and Deformation, and Sustainable Manufacturing Processes. - Provides theory, operational parameters, and latest developments in 20 different additive manufacturing processes - Includes contributions from experts in industry and academia with a wide range of disciplinary backgrounds, providing a comprehensive survey of this diverse and influential subject - Includes case studies of innovative additive manufacturing practices from industry