› › Modelling The Toxicity Of Nanoparticles

Model Organisms to Study Biological Activities and Toxicity of Nanoparticles

Author : Busi Siddhardha

Publisher : Springer Nature

Page : 466 pages

File Size : 15,35 MB

Release : 2020-03-28

Category : Medical

ISBN : 9811517029

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Book Description

This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.



Modelling the Toxicity of Nanoparticles

Author : Lang Tran

Publisher : Springer

Page : 360 pages

File Size : 42,50 MB

Release : 2017-02-06

Category : Medical

ISBN : 3319477544

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Book Description

In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.



Nanotoxicity

Author : Saura C. Sahu

Publisher : John Wiley & Sons

Page : 630 pages

File Size : 29,21 MB

Release : 2009-08-04

Category : Science

ISBN : 047074779X

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Book Description

Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.



Mixture Toxicity

Author : Cornelis A. M. van Gestel

Publisher : CRC Press

Page : 312 pages

File Size : 20,52 MB

Release : 2016-04-19

Category : Medical

ISBN : 1439830096

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Book Description

In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an



Toxicity of Nanomaterials

Author : Suresh C. Pillai

Publisher :

Page : 0 pages

File Size : 31,92 MB

Release : 2019

Category : Medical

ISBN : 9780429265471

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Book Description

Choice Recommended Title, April 2020 This comprehensive book, edited by two leading experts in nanotechnology and bioengineering with contributions from a global team of specialists, provides a detailed overview of the environmental and health impacts associated with the toxicology of nanomaterials. Special attention is given to nanomaterial toxicity during synthesis, production and application, and chapters throughout are focused on key areas that are important for future research and development of nanomaterials. This book will be of interest to advanced students studying biomedical engineering and materials science, PhD researchers, post-docs and academics working in the area of nanotechnology, medicine, manufacturing and regulatory bodies. Features: Collates and critically evaluates various aspects of the toxicology of nanomaterials in one comprehensive text Discusses the various effects of nanocrystals including the morphologies on cytotoxicity, in addition to the environmental and cytotoxicity risks of graphene and 2D nanomaterials Explores practical methods of detection and quantification, with applications in the environmental and healthcare fields



Silver Nanoparticles

Author : Khan Maaz

Publisher : Intechopen

Page : 290 pages

File Size : 18,49 MB

Release : 2018

Category : Technology & Engineering

ISBN : 1789234786

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Book Description

Silver nanoparticles are the subject of immense interest because of their distinct chemical and physical properties that are different from their bulk counterpart. This makes these nanoparticles very important in many fields including antimicrobial applications, biosensor materials, composite fibers, cryogenic superconducting materials, cosmetic products, and electronic components. This book aims to provide in-depth study and analysis of various fabrication, characterization, and application techniques of silver nanoparticles that lead these nanoparticles very important in the recent technology. This book presents deep understanding of the new techniques from basic to the advanced level. This book addresses scientists, engineers, doctoral and postdoctoral fellows, and technical professionals working in specialized fields.



The ELSI Handbook of Nanotechnology

Author : Chaudhery Mustansar Hussain

Publisher : John Wiley & Sons

Page : 597 pages

File Size : 26,67 MB

Release : 2020-03-31

Category : Technology & Engineering

ISBN : 1119592968

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Book Description

This Handbook focuses on the recent advancements in Safety, Risk, Ethical Society and Legal Implications (ESLI) as well as its commercialization of nanotechnology, such as manufacturing. Nano is moving out of its relaxation phase of scientific route, and as new products go to market, organizations all over the world, as well as the general public, are discussing the environmental and health issues associated with nanotechnology. Nongovernmental science organizations have long since reacted; however, now the social sciences have begun to study the cultural portent of nanotechnology. Societal concerns and their newly constructed concepts, show nanoscience interconnected with the economy, ecology, health, and governance. This handbook addresses these new challenges and is divided into 7 sections: Nanomaterials and the Environment; Life Cycle Environmental Implications of Nanomanufacturing; Bioavailability and Toxicity of Manufactured Nanoparticles in Terrestrial Environments; Occupational Health Hazards of Nanoparticles; Ethical Issues in Nanotechnology; Commercialization of Nanotechnology; Legalization of Nanotechnology.



Nanomaterials for Environmental Protection

Author : Boris I. Kharisov

Publisher : John Wiley & Sons

Page : 1449 pages

File Size : 15,83 MB

Release : 2014-08-27

Category : Technology & Engineering

ISBN : 1118845544

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Book Description

This book is divided into four main sections thoroughly analyzing the use of nanomaterials for water, air and soil solutions, and emphasizing environmental risks. Providing background on nanomaterials' two-decade study, it discusses the characterization and application of unconventional disinfectants, called antimicrobial nanomaterials, which fall into three categories and, while seemingly harmless, have potential hazards if applied improperly. Special attention is given to the process of remediation, synthetics techniques, and properties of nanomaterials, with examples to which new and trained readers in the field can relate and understand. an interdisciplinary approach, aimed at scientists in physical chemistry, nanotechnology, and environmental sciences includes applications of non-conventional techniques in environmental protection furthers the development of applied nanoscience and nanotechnology suggests new industrial projects and university courses addressing nanotechnology in and for the environment includes applications for water, air and soil protection



Biochemical Toxicology

Author : Muharrem Ince

Publisher : BoD – Books on Demand

Page : 232 pages

File Size : 46,81 MB

Release : 2020-07-29

Category : Medical

ISBN : 178984696X

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Book Description

Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.



Nanotechnology in Eco-Efficient Construction

Author : Fernando Pacheco-Torgal

Publisher : Elsevier

Page : 459 pages

File Size : 18,21 MB

Release : 2013-04-04

Category : Technology & Engineering

ISBN : 0857098837

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Book Description

As the environmental impact of existing construction and building materials comes under increasing scrutiny, the search for more eco-efficient solutions has intensified. Nanotechnology offers great potential in this area and is already being widely used to great success. Nanotechnology in eco-efficient construction is an authoritative guide to the role of nanotechnology in the development of eco-efficient construction materials and sustainable construction.Following an introduction to the use of nanotechnology in eco-efficient construction materials, part one considers such infrastructural applications as nanoengineered cement-based materials, nanoparticles for high-performance and self-sensing concrete, and the use of nanotechnology to improve the bulk and surface properties of steel for structural applications. Nanoclay-modified asphalt mixtures and safety issues relating to nanomaterials for construction applications are also reviewed before part two goes on to discuss applications for building energy efficiency. Topics explored include thin films and nanostructured coatings, switchable glazing technology and third generation photovoltaic (PV) cells, high-performance thermal insulation materials, and silica nanogel for energy-efficient windows. Finally, photocatalytic applications are the focus of part three, which investigates nanoparticles for pollution control, self-cleaning and photosterilisation, and the role of nanotechnology in manufacturing paints and purifying water for eco-efficient buildings.Nanotechnology in eco-efficient construction is a technical guide for all those involved in the design, production and application of eco-efficient construction materials, including civil engineers, materials scientists, researchers and architects within any field of nanotechnology, eco-efficient materials or the construction industry. - Provides an authoritative guide to the role of nanotechnology in the development of eco-efficient construction materials and sustainable construction - Examines the use of nanotechnology in eco-efficient construction materials - Considers a range of important infrastructural applications, before discussing applications for building energy efficiency