Models of Neurons and Perceptrons: Selected Problems and Challenges


Book Description

This book describes models of the neuron and multilayer neural structures, with a particular focus on mathematical models. It also discusses electronic circuits used as models of the neuron and the synapse, and analyses the relations between the circuits and mathematical models in detail. The first part describes the biological foundations and provides a comprehensive overview of the artificial neural networks. The second part then presents mathematical foundations, reviewing elementary topics, as well as lesser-known problems such as topological conjugacy of dynamical systems and the shadowing property. The final two parts describe the models of the neuron, and the mathematical analysis of the properties of artificial multilayer neural networks. Combining biological, mathematical and electronic approaches, this multidisciplinary book it useful for the mathematicians interested in artificial neural networks and models of the neuron, for computer scientists interested in formal foundations of artificial neural networks, and for the biologists interested in mathematical and electronic models of neural structures and processes.




Models of Neurons and Perceptrons


Book Description

This book describes models of the neuron and multilayer neural structures, with a particular focus on mathematical models. It also discusses electronic circuits used as models of the neuron and the synapse, and analyses the relations between the circuits and mathematical models in detail. The first part describes the biological foundations and provides a comprehensive overview of the artificial neural networks. The second part then presents mathematical foundations, reviewing elementary topics, as well as lesser-known problems such as topological conjugacy of dynamical systems and the shadowing property. The final two parts describe the models of the neuron, and the mathematical analysis of the properties of artificial multilayer neural networks. Combining biological, mathematical and electronic approaches, this multidisciplinary book it useful for the mathematicians interested in artificial neural networks and models of the neuron, for computer scientists interested in formal foundations of artificial neural networks, and for the biologists interested in mathematical and electronic models of neural structures and processes.




Artificial Intelligence for Health 4.0: Challenges and Applications


Book Description

Healthcare is one of the major success stories of our times. Medical science has improved rapidly, raising life expectancy around the world. However, as longevity increases, healthcare systems face growing demands for their services, rising costs, and a workforce that is struggling to meet the needs of its patients. Healthcare is one of the most critical sectors in the broader landscape of big data because of its fundamental role in a productive, thriving society. Building on automation, artificial intelligence (AI) has the potential to revolutionize healthcare and help address some of the challenges set out above. The application of AI to healthcare data can literally be a matter of life and death. AI can assist doctors, nurses, and other healthcare workers in their daily work. AI in healthcare can enhance preventive care and quality of life, produce more accurate diagnoses and treatment plans, and lead to better patient outcomes overall. This book gives insights into the latest developments of applications of AI in biomedicine, including disease diagnostics, pharmaceutical processing, patient care and monitoring, biomedical information, and biomedical research. It also presents an outline of the recent breakthroughs in the application of AI in healthcare, describes a roadmap to building effective, reliable, and safe AI systems, and discusses the possible future direction of AI augmented healthcare systems. AI has countless applications in healthcare. Whether it’s being used to discover links between genetic codes, to power surgical robots or even to maximize hospital efficiency; AI has been a boon to the healthcare industry.




Artificial Intelligence in Daily Life


Book Description

Given the exponential growth of Artificial Intelligence (AI) over the past few decades, AI and its related applications have become part of daily life in ways that we could never have dreamt of only a century ago. Our routines have been changed beyond measure by robotics and AI, which are now used in a vast array of services. Though AI is still in its infancy, we have already benefited immensely. This book introduces readers to basic Artificial Intelligence concepts, and helps them understand the relationship between AI and daily life. In the interest of clarity, the content is divided into four major parts. Part I (AI Concepts) presents fundamental concepts of and information on AI; while Part II (AI Technology) introduces readers to the five core AI Technologies that provide the building blocks for various AI applications, namely: Machine Learning (ML), Data Mining (DM), Computer Vision (CV), Natural Languages Processing (NLP), and Ontology-based Search Engine (OSE). In turn, Part III (AI Applications) reviews major contemporary applications that are impacting our ways of life, working styles and environment, ranging from intelligent agents and robotics to smart campus and smart city projects. Lastly, Part IV (Beyond AI) addresses related topics that are vital to the future development of AI. It also discusses a number of critical issues, such as AI ethics and privacy, the development of a conscious mind, and autonomous robotics in our daily lives.




Biosimilars Development Strategies


Book Description

After 18 years since the first biosimilar was approved, a lot has changed, from the regulatory guidelines to the stakeholder perceptions about the safety and efficacy of biosimilars. However, the development costs remain high, preventing faster entry into markets with more than 200 choices. Analyzing the regulatory filings of all approved biosimilars in the US and EU, a deep analysis of the scientific principles, and continuous challenges to the regulatory authorities have made it possible to plan the development on a fast track. This book teaches how to cut the current time and cost by more than 70%, based on the author's hands-on experience. Features: Describes the emergence of biosimilars since the first publication of the recombinant engineering patent, as well as a listing of all approved recombinant products, their patent expiry and their adoption across the globe. Provides a better understanding of the safety and efficacy of approved biosimilars. Global approval requires accommodating guidelines and detailed planning to avoid redundancy as well as high costs. The basic expectations of the agencies are presented here. Presents a detailed analysis of all EU and FDA-approved products with a comparative analysis. Renowned author and entrepreneur in the field of drug discovery and production.




Handbook of Geospatial Artificial Intelligence


Book Description

This comprehensive handbook covers Geospatial Artificial Intelligence (GeoAI), which is the integration of geospatial studies and AI machine (deep) learning and knowledge graph technologies. It explains key fundamental concepts, methods, models, and technologies of GeoAI, and discusses the recent advances, research tools, and applications that range from environmental observation and social sensing to natural disaster responses. As the first single volume on this fast-emerging domain, Handbook of Geospatial Artificial Intelligence is an excellent resource for educators, students, researchers, and practitioners utilizing GeoAI in fields such as information science, environment and natural resources, geosciences, and geography. Features Provides systematic introductions and discussions of GeoAI theory, methods, technologies, applications, and future perspectives Covers a wide range of GeoAI applications and case studies in practice Offers supplementary materials such as data, programming code, tools, and case studies Discusses the recent developments of GeoAI methods and tools Includes contributions written by top experts in cutting-edge GeoAI topics This book is intended for upper-level undergraduate and graduate students from different disciplines and those taking GIS courses in geography or computer sciences as well as software engineers, geospatial industry engineers, GIS professionals in non-governmental organizations, and federal/state agencies who use GIS and want to learn more about GeoAI advances and applications.




Innovative Product Design and Intelligent Manufacturing Systems


Book Description

This book gathers selected research articles from the International Conference on Innovative Product Design and Intelligent Manufacturing System (ICIPDIMS 2019), held at the National Institute of Technology, Rourkela, India. The book discusses latest methods and advanced tools from different areas of design and manufacturing technology. The main topics covered include design methodologies, industry 4.0, smart manufacturing, and advances in robotics among others. The contents of this book are useful for academics as well as professionals working in industrial design, mechatronics, robotics, and automation.




From Current to Future Trends in Pharmaceutical Technology


Book Description

From Current to Future Trends in Pharmaceutical Technology explores the current trends of this field and creates a multi-aspect framework for the reader. The book covers topics on pharmaceutics, pharmaceutical engineering, pre-formulation protocols, techniques, innovative excipients, bio-printing techniques, scale-up based on formulas on-a-chip, and regulatory aspects based on new scientific achievements. Modified dosage forms, new aspects on the compatibility of drug excipients interactions, and drug release by various dosage forms are included. Physical pharmacy (physical and biological stability of dosage forms), innovative excipients, patents on innovative formulations and regulatory issues related to the approval process of medicines are also discussed. The book is a valuable resource for a wide audience of academics, industrial researchers and professionals working in this field as the development of efficient and safe medicines is critical to future needs. - Includes innovative excipients/advanced materials in pharmaceutics - Covers modified release delivery platforms - Explores new elements of drug development




The Future of Pharmaceutical Product Development and Research


Book Description

The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques




Recent Advances in Pharmaceutical Innovation and Research


Book Description

This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.