Multiphase Biomedical Materials


Book Description

Following many reports that were published in the last two decades on correlations of multiphase structures of the surface of materials with their antithrombogenicity or biocompatibility a research project ''Design of Multiphase Biomedical Materials'' was carried out in Japan between 1982 and 1986. The objective of this research project was to elucidate various aspects of biomedical behaviour of multiphase systems at the interface with living bodies at the molecular, cellular and tissue levels. Multiphase materials studied cover polymers having microphase-separated structures, hydrogels, immobilized enzymes (or cells), ceramics and metallic materials. The research project was carried out by the following subgroups: -- Multiphase biomedical materials with microdomain structures -- Multiphase biomedical materials containing liquid components -- Hybrid-type multiphase biomedical materials with biological components -- Inorganic and metallic multiphase biomedical materials -- Methods for analysis and evaluation of multiphase biomedical materials This book contains the results of the research project in an edited form and aims to provoke a better understanding about various aspects of cell--material interactions in which the multiphase systems play a crucial role.




Multiphase Biomedical Materials


Book Description

Following many reports that were published in the last two decades on correlations of multiphase structures of the surface of materials with their antithrombogenicity or biocompatibility a research project ''Design of Multiphase Biomedical Materials'' was carried out in Japan between 1982 and 1986. The objective of this research project was to elucidate various aspects of biomedical behaviour of multiphase systems at the interface with living bodies at the molecular, cellular and tissue levels. Multiphase materials studied cover polymers having microphase-separated structures, hydrogels, immobilized enzymes (or cells), ceramics and metallic materials. The research project was carried out by the following subgroups: -- Multiphase biomedical materials with microdomain structures -- Multiphase biomedical materials containing liquid components -- Hybrid-type multiphase biomedical materials with biological components -- Inorganic and metallic multiphase biomedical materials -- Methods for analysis and evaluation of multiphase biomedical materials This book contains the results of the research project in an edited form and aims to provoke a better understanding about various aspects of cell--material interactions in which the multiphase systems play a crucial role.




Polymer Biomaterials in Solution, as Interfaces and as Solids


Book Description

The articles collected in this publication have previously been published in eight special issues of the Journal of Biomaterials Science, Polymer Edition, in honour of Dr. Allan S. Hoffman, who is known as a pioneer, a leader and a mentor in the field of biomaterials. The papers from renowned scientists from all parts of the world, representing the




The Biomaterials: Silver Jubilee Compendium


Book Description

The journal Biomaterials was launched in 1980. The subject of biomaterials science was then in its infancy, being largely cofined to the study of the characteristics of materials used for medical devices.Twenty-five years on, we can truly say that biomaterials science has matured at an incredible rate and now represents a formidable sector that bridges the materials sciences, advanced medical therapies, and molecular and cell sciences.This Silver Jubilee Compendium consists of reprinted versions of the top 25 papers, published during these 25 years, as judged by an international panel of biomaterials scientists.This book is published as a landmark in biomaterials science and it is to be hoped that it will serve as a stimulus to young biomaterials scientists of the early twenty-first century for their pioneering work of the future.




Transport Phenomena in Multiphase Systems


Book Description

Engineering students in a wide variety of engineering disciplines from mechanical and chemical to biomedical and materials engineering must master the principles of transport phenomena as an essential tool in analyzing and designing any system or systems wherein momentum, heat and mass are transferred. This textbook was developed to address that need, with a clear presentation of the fundamentals, ample problem sets to reinforce that knowledge, and tangible examples of how this knowledge is put to use in engineering design. Professional engineers, too, will find this book invaluable as reference for everything from heat exchanger design to chemical processing system design and more. * Develops an understanding of the thermal and physical behavior of multiphase systems with phase change, including microscale and porosity, for practical applications in heat transfer, bioengineering, materials science, nuclear engineering, environmental engineering, process engineering, biotechnology and nanotechnology * Brings all three forms of phase change, i.e., liquid vapor, solid liquid and solid vapor, into one volume and describes them from one perspective in the context of fundamental treatment * Presents the generalized integral and differential transport phenomena equations for multi-component multiphase systems in local instance as well as averaging formulations. The molecular approach is also discussed with the connection between microscopic and molecular approaches * Presents basic principles of analyzing transport phenomena in multiphase systems with emphasis on melting, solidification, sublimation, vapor deposition, condensation, evaporation, boiling and two-phase flow heat transfer at the micro and macro levels * Solid/liquid/vapor interfacial phenomena, including the concepts of surface tension, wetting phenomena, disjoining pressure, contact angle, thin films and capillary phenomena, including interfacial balances for mass, species, momentum, and energy for multi-component and multiphase interfaces are discussed * Ample examples and end-of-chapter problems, with Solutions Manual and PowerPoint presentation available to the instructors




Manipulation of Multiphase Materials for Touch-less Nanobiotechnology


Book Description

The thesis presents an original and smart way to manipulate liquid and polymeric materials using a “pyro-fluidic platform” which exploits the pyro-electric effect activated onto a ferroelectric crystal. It describes a great variety of functionalities of the pyro-electrohydrodynamic platform, such as droplet self-assembling and dispensing, for manipulating multiphase liquids at the micro- and nanoscale. The thesis demonstrates the feasibility of non-contact self-assembling of liquids in plane (1D) using a micro engineered crystal, improving the dispensing capability and the smart transfer of material between two different planes (2D) and controlling and fabricating three-dimensional structures (3D). The thesis present the fabrication of highly integrated and automated ‘lab-on-a-chip’ systems based on microfluidics. The pyro-platform presented herein offers the great advantage of enabling the actuation of liquids in contact with a polar dielectric crystal through an electrode-less configuration. The simplicity and flexibility of the method for fabricating 3D polymer microstructures shows the great potential of the pyro-platform functionalities, exploitable in many fields, from optics to biosensing. In particular, this thesis reports the fabrication of optically active elements, such as nanodroplets, microlenses and microstructures, which have many potential applications in photonics. The capability for manipulating the samples of interest in a touch-less modality is very attractive for biological and chemical assays. Besides controlling cell growth and fate, smart micro-elements could deliver optical stimuli from and to cells monitoring their growth in real time, opening interesting perspectives for the realization of optically active scaffolds made of nanoengineered functional elements, thus paving the way to fascinating Optogenesis Studies.




Biomedical Materials and Diagnostic Devices


Book Description

Biomedical Materials and Diagnostics Devices provides an up-to-date overview of the fascinating and emerging field of biomedical materials and devices, fabrication, performance, and uses The biomedical materials with the most promising potential combine biocompatibility with the ability to adjust precisely the biological phenomena in a controlled manner. The world market for biomedical and diagnostic devices is expanding rapidly and the pace of academic research resulted in about 50,000 published papers in recent years. It is timely, therefore, to assemble a volume on this important subject. The chapters in the book seek to address progress in successful design strategies for biomedical materials and devices such as the use of collagen, crystalline calcium orthophosphates, amphiphilic polymers, polycaprolactone, biomimetic assembly, bio-nanocomposite matrices, bio-silica, theranostic nanobiomaterials, intelligent drug delivery systems, elastomeric nanobiomaterials, electrospun nano-matrices, metal nanoparticles, and a variety of biosensors. This large and comprehensive volume includes twenty chapters authored by some of the leading researchers in the field, and is divided into four main areas: biomedical materials; diagnostic devices; drug delivery and therapeutics; and tissue engineering and organ regeneration.




Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems


Book Description

First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.




Biomaterials, Artificial Organs and Tissue Engineering


Book Description

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs.Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. - Comprehensive introduction to living and man-made materials - Looks at clinical applications of various biomaterials and devices - Bioengineering principles, materials and designs used in artificial organs are summarised




High Performance Biomaterials


Book Description

Encyclopedic presentation of the clinical applications of biomaterials from markets and advanced concepts to pharmaceutical applications and blood compatibility.