Myelodysplastic Syndromes, An Issue of the Clinics in Laboratory Medicine, E-Book


Book Description

In this issue of Clinics in Laboratory Medicine, guest editor Dr. Alexa J. Siddon brings her considerable expertise to the topic of Myelodysplastic Syndromes. Top experts in the field discuss the various aspects of rare myelodysplastic syndromes and its treatments, detection, and characteristics. Topics include molecular changes in myelodysplastic syndromes; MDS with mutated SF3B1; myeloid neoplasms with mutated TP53; mimics of myelodysplastic syndromes; myeloid neoplasms with germline predisposition; and more. - Contains 12 practice-oriented topics including premalignant clonal hematopoiesis (CHIP and CCUS); morphologic characteristics of MDS; acute leukemia arising from MDS; treatment considerations of MDS for pathologists; and more. - Provides in-depth clinical reviews on myelodysplastic syndromes, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Flow Cytometry, An Issue of Clinics in Laboratory Medicine


Book Description

This issue of Clinics in Laboratory Medicine, edited by David M. Dorfman, will cover Flow Cytometry. Topics covered in this issue include: Flow cytometric evaluation of primary immunodeficiencies; Flow cytometry of B cell neoplasms; Flow cytometry of T cell neoplasms; Flow cytometry of acute myeloid leukemias; AML minimal residual disease (MRD) assessment by flow cytometric analysis; Acute lymphoblastic leukemia minimal residual disease (MRD) assessment by flow cytometric analysis; Flow cytometric assessment of myelodysplasia and myeloproliferative neoplasms; Flow cytometry of plasma cell neoplasms, including MRD testing; Paroxysmal nocturnal hemoglobinuria (PNH) assessment by flow cytometric analysis; Mast cell disease assessment by flow cytometric analysis; Flow cytometry in pediatric hematopathology; Clinical applications of mass cytometry; Automated analysis of clinical flow cytometry data; and Cost-effective flow cytometric testing strategies.




Orthobiologics, An Issue of Physical Medicine and Rehabilitation Clinics of North America, E-Book


Book Description

In this issue of Physical Medicine and Rehabilitation Clinics, guest editors Drs. Michael Khadavi and Luga Podesta bring their considerable expertise to the topic of Orthobiologics. Use and research surrounding naturally derived substances that are used to help heal and repair orthopedic injuries are expanding rapidly. In this issue, top experts discuss the most up-to-date uses of orthobiologics in the rehabilitation setting. - Contains 16 practice-oriented topics including orthobiologics for spine disorders; evidence and techniques in prolotherapy; orthobiologic interventions for muscle injuries; special populations in orthobiologics: athletic, elderly, and pediatrics populations; rehabilitation protocols for orthobiologic procedures; orthobiologic techniques for surgical augmentation; and more. - Provides in-depth clinical reviews on orthobiologics, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Anemia in Older Adults, An Issue of Clinics in Geriatric Medicine


Book Description

This issue of Clinics in Geriatric Medicine, Guest Edited by William B. Ershler, MD of the Institute for Advanced Studies in Aging and Geriatric Medicine, is devoted to Anemia in the Older Adult. Articles in this important issue include: Aging and Hematopoiesis; Prevalence of Anemia in Older Populations; Functional Consequences of Anemia in Older Patients; Mechanisms of Anemia in Older Populations; Unexplained Anemia in Older Populations; Significance of Elevated RDW in Older Populations; Iron Deficiency; Vitamin B12; Myelodysplasia; Chronic Kidney Disease and Anemia in Older Populations; Inflammation, Aging and Anemia; Emergence of Sickle Cell Disease in Older Populations; Heyde’s Syndrome; and Special Considerations for Anemia in the Nursing Home.




ISCN 2013


Book Description

This publication extends the now classic system of human cytogenetic nomenclature prepared by an expert committee and published in collaboration with Cytogenetic and Genome Research' since 1963. Revised and finalized by the ISCN Committee and its advisors at a meeting in Seattle, Wash., in April 2012, the ISCN 2013 updates, revises and incorporates all previous human cytogenetic nomenclature recommendations into one systematically organized publication that supersedes all previous ISCN recommendations. There are several new features in ISCN 2013: an update of the microarray nomenclature, many more illustrative examples of uses of nomenclature in all sections some definitions including chromothripsis and duplication a new chapter for nomenclature that can be used for any region-specific assay. The ISCN 2013 is an indispensable reference volume for human cytogeneticists, technicians and students for the interpretation and communication of human cytogenetic nomenclature.




Pediatric Hematology, An Issue of Pediatric Clinics


Book Description

This issue will assist the practicing pediatrician with providing evidence-based care to children with common, rare, inherited and acquired hematological disorders whom they regularly see in general pediatric practice. The information in this edition will support a general pediatrician’s understanding of recently developed diagnostic and therapeutic tools--for instance, techniques for the assessment of transfusional iron overload in chronically transfused patients – resulting in better surveillance of medication side effects and improved support for patients who are prescribed with complex chelation regimens. New, improved therapeutic approaches to treatment of children with venous thromboembolic disease have recently been introduced; affected patients often require close monitoring in their communities through the general pediatrician whose practice will be enhanced by information that has been prepared by pediatric specialists with pediatric patients in mind.




100 Questions and Answers about Myelodysplastic Syndromes


Book Description

Newly revised and updated, 100 Questions & Answers About Myelodysplastic Syndromes provides authoritative and practical answers to the most common questions asked by patients and their loved ones. What is myelodysplastic syndromes (MDS)? What causes MDS? Is MDS hereditary, and will I give it to my children? Written by experts in the field, and with commentary from actual patients, this guide is the only text available to provide both the doctor's and patient's views.100 Questions & Answers About Myelodysplastic Syndromes is an invaluable resource for anyone struggling with the medical, physical, and emotional turmoil of this disease.




Boundaryless Hospital


Book Description

This book discusses current health care challenges and new strategies for innovative solutions in this area from an interdisciplinary perspective of health care management, business economics, and medicine. It presents the idea of a “boundaryless hospital”, a conceptual model of a patient-centric, value-based health network that overcomes typical sectorial, organizational, and geographical boundaries and offers greater efficiency and better quality outcomes for patients. Effective health care for a growing and aging population is a major challenge for economies all over the world. New breakthroughs in medical technology and pharmaceuticals as well as digitization provide scope for more efficiency and for a better quality of health care. Novel organization forms and management concepts are key for coping with the increasing cost pressure observed in most health care systems. The contributions in this volume present innovative strategies for developing and implementing the concept of a boundaryless hospital. They highlight experiences from various countries and with different treatments. The book project was initiated and carried out by the Center for Advanced Studies in Management (CASiM), the interdisciplinary research center of HHL Leipzig Graduate School of Management for business administration in the 21st century.




Bone Marrow Pathology


Book Description

Written by one of the world's leading haematologists, and three renowned histopathologists, Bone Marrow Pathology provides a comprehensive guide to the diagnosis of bone marrow disease. Now in its Third Edition, the text has been extensively revised and rewritten to reflect the latest advances in the field. Features: An extremely practical, up-to-the-minute text incorporating the new WHO classification of haematopoietic malignancies A comprehensive text written with great precision and clarity of style Incorporates a new section 'Problems and Pitfalls' - a unique section that will aid the working pathologist faced with a difficult situation An important text for the haematologist, histopathologist and haematopathologist with equal weight given to peripheral blood, aspirate, trephine biology and specialized techniques Extensively illustrated with many of the photographs being of paraffin-embedded sections Combines all the techniques now applied to bone marrow diagnosis, including immunocytochemistry, flow cytometery, immunohistochemistry and the diagnostic role of cytogenetic and molecular genetic analysis




Clinical Hematology and Fundamentals of Hemostasis


Book Description

A concise and thorough guide to clinical hematology and the fundamentals of hemostasis. The text's five parts provide a substantial introduction to the subject, followed by sections on the anemias, white blood cell disorders, hemostasis/thrombosis, and laboratory methods. This edition includes new chapters addressing the use of flow cytometry, the molecular diagnostic techniques in hematopathology, and an introduction to thrombosis and anticoagulant therapy. A feature of previous editions, a 260-page color-plate atlas, has been incorporated throughout the text. Annotation copyright by Book News, Inc., Portland, OR