Natural Products and Nano-Formulations in Cancer Chemoprevention


Book Description

This book covers various aspects of cancer chemoprevention, including an overview of chemoprevention in the process of tumorigenesis; the roles of various phytochemicals, functional foods, and dietary interventions in disease prevention; and techniques such as cancer stem cell targeting, nano-formulations, and so forth. The nutrigenomic and epigenetic effects of natural products at the molecular and genetic levels are also covered alongside their potential for additive and synergistic effect, as well as overcoming drug resistance. The key selling features of the book are as follows: Discusses holistic and comprehensive areas of chemoprevention Includes diverse techniques, such as cancer stem cell targeting, nano-formulations, and nanotechnology-based drug delivery systems Introduces various mechanisms involved in prevention of the diseases, including targeting cancer stem cells Reviews various aspects which can reduce the toxicity and cost of treatment of diseases by alternative medicine Explores various sources, mechanisms, and ways to develop cancer chemopreventive agents with minimal toxicity compared to traditional cancer therapy drugs This book is focused on researchers and graduate students in drug delivery and formulation, nanobiotechnology, cancer chemoprevention, prevention, and therapeutics.




Plant Secondary Metabolites


Book Description

Plant secondary metabolites have been a fertile area of chemical investigation for many years, driving the development of both analytical chemistry and of new synthetic reactions and methodologies. The subject is multi-disciplinary with chemists, biochemists and plant scientists all contributing to our current understanding. In recent years there has been an upsurge in interest from other disciplines, related to the realisation that secondary metabolites are dietary components that may have a considerable impact on human health, and to the development of gene technology that permits modulation of the contents of desirable and undesirable components. Plant Secondary Metabolites: Occurrence, Structure and Role in the Human Diet addresses this wider interest by covering the main groups of natural products from a chemical and biosynthetic perspective with illustrations of how genetic engineering can be applied to manipulate levels of secondary metabolites of economic value as well as those of potential importance in diet and health. These descriptive chapters are augmented by chapters showing where these products are found in the diet, how they are metabolised and reviewing the evidence for their beneficial bioactivity.




Natural Products for Cancer Chemoprevention


Book Description

This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.




Nanostructures for Antimicrobial Therapy


Book Description

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area




Bioactive Natural Products for the Management of Cancer: from Bench to Bedside


Book Description

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer. Recent research and development efforts concerning anti-cancer drugs derived from natural products have led to the identification of numerous candidate molecules that inhibit cancer cell proliferation and metastasis using a variety of mechanisms. Given its scope, the book offers a valuable resource for cancer biologists and general oncologists alike, while also benefitting research professionals in Science, Nursing, Medicine, Biochemistry, Genetics and Bioscience who wish to understand the fundamentals of prognosis and prediction in tumorigenesis. Moreover, the book provides an essential platform for understanding drug resistance mechanisms and combatting the growing menace of multidrug resistance.




Cancer Chemoprevention


Book Description

This volume presents state of the art of methods that can be useful for both basic and translational researchers to conduct chemoprevention preclinical studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cancer Chemoprevention: Methods and Protocols aims to ensure successful results in the further study of this vital field.




Nutraceuticals and Cancer


Book Description

This book is about Nutraceuticals in cancer therapy, specifically targeted and Adjuvant therapy. It shows several approaches for possibly reducing systemic toxicity. This book illustrates the role of several dietary agents, collectively called nutraceuticals or natural agents in the prevention and/or treatment of human malignancies known to be mediated through alterations in multiple molecular targets. This book contains sixteen chapters which begin with historical perspective on the value of natural agents in the prevention of human malignancies followed by a series of current topics on multiple nutraceuticals targeting multiple cancers. This collection would likely be useful for bringing newer generations with broader perspectives in launching cutting-edge innovative molecular research, which would certainly help in designing targeted clinical trials in order to realize the dream of customize strategies for the prevention and/or treatment of human malignancies without causing any systemic toxicity. Moreover, the knowledge gained would allow novel utilization of nutraceuticals as adjunct to both conventional chemotherapy and radiation therapy in order to improve the overall quality of life and survival of patients diagnosed with cancers.




Cancer Chemoprevention


Book Description

Accompanying CD-ROM in pocket at end of v. 2 contains a compact e-book version of v. 2.




Bionanotechnology for Advanced Applications


Book Description

This book provides the fundamental aspects of bionanomaterials and bionanotechnology, and insight into the synthesis and modification of bionanomaterials in a detailed manner. It initiates with a general overview of biotechnology and nanotechnology followed by different strategies and methodologies for the synthesis of nanomaterials. Further, it discusses pertinent topics such as protein engineering, analysis, mechanisms of microbe- mediated nanosynthesis, followed by various challenges and innovation strategies, and the role of enzymes in bionanotechnology. Features: Covers the synthesis of bionanomaterials, including the interaction between nanomaterial and biogenic materials Encompasses the study of the connections between structure, molecular biology, and nanotechnology Explains several techniques (XRD, SEM, TEM, etc.) used for the analysis of bionanomaterials Includes prospects, challenges, and opportunities associated with bionanotechnology Reviews the interaction between nanomaterials and the biological system and self- assembly in bionanotechnology This book is aimed at graduate students and researchers in materials sciences, biotechnology, and bionanotechnology.




Bionanotechnology Towards Green Energy


Book Description

Bionanotechnology Towards Green Energy explains the role of bionanotechnology in the next generation technologies of green energy from an interdisciplinary and sustainability perspective. Chapters cover different roles of bionanotechnology such as applications of bio-nano enabled materials/coatings, scaling-up of green energy production, design and synthesis of bio-inspired nanomaterials and their applications, bio-nanofluid-based photovoltaic thermal systems, the use of bio-templated and biomimetic materials, and so forth. It focuses on waste-to-energy conversion and fixing intricate environmental issues. Key features: Provides detailed coverage of green energy production through bionanotechnological intervention Reviews future research needs in bionanotechnology in the green energy sector and scientific challenges in the mitigation of energy crises Deals with cutting-edge research on microbial synergism in biohydrogen production and storage Discusses the fabrication of bio-nano/hybrid electrode materials for supercapacitors and energy storage devices Includes extensive illustrations, case studies, summary tables, and up-to-date references This book is aimed at researchers and professionals in bionanotechnology, energy sciences, and environmental engineering.