Neonatal Encephalopathy and Neurologic Outcome


Book Description

Significantly revised and updated, the new second edition updates the science on neonatal encephalopathy presented in the 1st edition. The new 2nd edition recommends a broad evaluation of all potential contributing factors in every case of neonatal encephalopathy, including maternal medical history, obstetric and intrapartum factors, and placental pathology. This recommendation is a shift from the 2003 report, which focused on determining whether or not a hypoxic-ischemic event was the cause of neonatal encephalopathy. Includes new sections on - Placental pathology - Focal ischemic stroke - Neonatal interventions - Patient safety - Significant advances in neuroimaging This report will assist the clinician in evaluating a newborn with encephalopathy to assist in defining both the cause and timing.




Neonatal Encephalopathy and Cerebral Palsy


Book Description

This monograph explores the mechanisms and timing of possible etiologic events that contribute to fetal and neonatal neurologic injury. the report presents evidence that most cases of cerebral palsy are a result of multifactorial and unpreventable causes that occur during fetal development or in the newborn after delivery, and not a result of an isolated intrapartum hypoxic event. the report contains a set of criteria that may be used to define (or rule out) an acute intrapartum hypoxic event sufficient to cause or suggest cerebral palsy.




The Newborn Brain


Book Description

Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.




The Epilepsies


Book Description

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.




Follow-Up for NICU Graduates


Book Description

This book examines the role of Neonatal Intensive Care Units (NICUs) and follow-up clinics in addressing the complex developmental, behavioral, social, and medical needs of at-risk infants through early intervention and medical subspecialties. It describes the necessary functional components of follow-up clinics and challenges in establishing and running multidisciplinary clinics in an area of difficult heath care financing. Chapters provide essential guidelines for determining which neonates will need follow-up care, evaluating for neurodevelopmental delays and medical and behavioral impairment and disability, and estimating how long intervention and further follow-up will be required. Chapters also discuss organization, staffing, funding, testing protocols, and coordination with other programs and care facilities, particularly early intervention and the medical home. In addition, the book offers best practices for fostering optimal development for individual infants and high-risk populations while raising standards for neonatal care and creating a smooth transition to appropriate subsequent care. Topics featured in this book include: Developmental care in the nursery. Utilizing neonatal brain imaging to predict neurodevelopmental outcomes of NICU infants. Genetic considerations in infants with congenital anomalies. The HRIF clinic organization model. Issues common in neurodevelopmental testing of premature infants. The impact of environmental risks, such as parental distress and in-utero drug exposure, to infant neurodevelopment. Follow-Up for NICU Graduates is a must-have resource for researchers, practitioners, and graduate students in developmental psychology, pediatrics, neuroscience, obstetrics, nursing, and related disciplines.




ADHD Rating Scale?5 for Children and Adolescents


Book Description

Preceded by ADHD rating scale-IV / George J. DuPaul ... [et al.]. 1998.




Cerebral Palsy


Book Description

When a child has a health problem, parents want answers. But when a child has cerebral palsy, the answers don't come quickly. A diagnosis of this complex group of chronic conditions affecting movement and coordination is difficult to make and is typically delayed until the child is eighteen months old. Although the condition may be mild or severe, even general predictions about long-term prognosis seldom come before the child's second birthday. Written by a team of experts associated with the Cerebral Palsy Program at the Alfred I. duPont Hospital for Children, this authoritative resource provides parents and families with vital information that can help them cope with uncertainty. Thoroughly updated and revised to incorporate the latest medical advances, the second edition is a comprehensive guide to cerebral palsy. The book is organized into three parts. In the first, the authors describe specific patterns of involvement (hemiplegia, diplegia, quadriplegia), explain the medical and psychosocial implications of these conditions, and tell parents how to be effective advocates for their child. In the second part, the authors provide a wealth of practical advice about caregiving from nutrition to mobility. Part three features an extensive alphabetically arranged encyclopedia that defines and describes medical terms and diagnoses, medical and surgical procedures, and orthopedic and other assistive devices. Also included are lists of resources and recommended reading.




Magnetic Resonance of Myelin, Myelination, and Myelin Disorders


Book Description

Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the majority of disorders affecting the central nervous system. This is particularly true for gray and white matter disorders, thanks to the superb soft tis sue contrast in MRI which allows gray matter, unmyelinated, and myelinated white matter to be distinguished and their respective disorders identified. The pre sent book is devoted to the disorders of myelin and myelination. A growing amount of detailed in vivo information about myelin, myelination, and myelin dis orders has been derived both from MRI and from MR spectroscopy (MRS). This prompted us to review the clinical, laboratory, biochemical, and pathological data on this subject in order to integrate all available information and to provide im proved insights into normal and disordered myelin and myelination. We will show how the synthesis of all available information contributes to the interpretation of MR images. After a brief historical review about the increasing knowledge on myelin and my elin disorders, we propose a new classification of myelin disorders based on the subcellular localization of the enzymatic defects as far as the inborn errors of me tabolism are concerned. This classification serves as a guide throughout the book. All items of the classification will be discussed and, whenever relevant and possi ble, be illustrated by MR images.




Neonatal Neural Rescue


Book Description

Worldwide more than one million babies die annually from perinatal asphyxia and its associated complications such as neonatal encephalopathy - one of the major causes of cerebral palsy and cognitive deficiencies in children aside from prematurity. Cooling the head - or the entire body - minimizes neuronal death, enabling the neonatal brain to be 'rescued' thus greatly improving developmental outcomes. Hypothermic neural rescue therapy has revolutionized the treatment of this condition and is a major recent achievement in neonatal medicine. This landmark book provides a brief scientific underpinning of hypothermic neural rescue therapy and lays out the evidence base for good practice. Internationally recognized authorities give practical advice, drawn from personal experience, on how to deliver hypothermia in the neonatal intensive care unit. A valuable addition to any neonatal unit, this is essential reading for neonatologists, neonatal nurses and paediatric neurologists.




Obstetric Interventions


Book Description