Neural Substrates of Memory, Affective Functions, and Conscious Experience


Book Description

It is important, indeed necessary, we believe, that the study of the higher brain func tions be introduced by a brief account of the evolution of the philosophical thinking and scientific researches on cognition. The intuition that sensations and intelligence reside in the brain goes back to the Egyptians, in particular the Edwin Smith papyrus, probably dated between 2500 and 3000 b. c. , where the term "brain" appears for the first time and where there is a description of its coverings (meninges) and circumvolutions (Walsh 1994). The philosophical debate on brain and mind made its appearance in ancient l Greece and in subsequent centuries developed among the philosophers. The flow of sensations, the process of thinking, and the site of reason were localized in the brain, according to Alcmaeon of Croton (sixth to fifth centuries b. c. ) and subsequently Lattanzio, Alexander of Tralles, Democritus, Anaxagoras, and particularly Hip pocrates (460-377 b. c. ), who placed the soul, envisaged as a mental function, in the brain. Plato (427-347 b. c. ) believed that the brain provided the sensory experiences (hearing, sight, smell) and that from these were generated thinking and memory, and the act of thinking produced the truth or "episteme. " The formulation of the problem changes radically with Aristotle (384-322 b. c. ), who believed that the heart, and not the brain, was the site of passions, feelings, intelligence, and thought (Gross 1995).







Index Medicus


Book Description

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.




Cognitive Neuroscience of Emotion


Book Description

This book, a member of the Series in Affective Science, is a unique interdisciplinary sequence of articles on the cognitive neuroscience of emotion by some of the most well-known researchers in the area. It explores what is known about cognitive processes in emotion at the same time it reviews the processes and anatomical structures involved in emotion, determining whether there is something about emotion and its neural substrates that requires they be studied as a separate domain. Divided into four major focal points and presenting research that has been performed in the last decade, this book covers the process of emotion generation, the functions of amygdala, the conscious experience of emotion, and emotion regulation and dysregulation. Collectively, the chapters constitute a broad but selective survey of current knowledge about emotion and the brain, and they all address the close association between cognitive and emotional processes. By bringing together diverse strands of investigation with the aim of documenting current understanding of how emotion is instantiated in the brain, this book will be of use to scientists, researchers, and advanced students of psychology and neuroscience.




Predictions in the Brain


Book Description

When one is immersed in the fascinating world of neuroscience findings, the brain might start to seem like a collection of "modules," each specializes in a specific mental feat. But just like in other domains of Nature, it is possible that much of the brain and mind's operation can be explained with a small set of universal principles. Given exciting recent developments in theory, empirical findings and computational studies, it seems that the generation of predictions might be one strong candidate for such a universal principle. This is the focus of Predictions in the brain. From the predictions required when a rat navigates a maze to food-caching in scrub-jays; from predictions essential in decision-making to social interactions; from predictions in the retina to the prefrontal cortex; and from predictions in early development to foresight in non-humans. The perspectives represented in this collection span a spectrum from the cellular underpinnings to the computational principles underlying future-related mental processes, and from systems neuroscience to cognition and emotion. In spite of this diversity, they share some core elements. Memory, for instance, is critical in any framework that explains predictions. In asking "what is next?" our brains have to refer to memory and experience on the way to simulating our mental future. But as much as this collection offers answers to important questions, it raises and emphasizes outstanding ones. How are experiences coded optimally to afford using them for predictions? How do we construct a new simulation from separate memories? How specific in detail are future-oriented thoughts, and when do they rely on imagery, concepts or language? Therefore, in addition to presenting the state-of-the-art of research and ideas about predictions as a universal principle in mind and brain, it is hoped that this collection will stimulate important new research into the foundations of our mental lives.




Consciousness and the Brain


Book Description

WINNER OF THE 2014 BRAIN PRIZE From the acclaimed author of Reading in the Brain and How We Learn, a breathtaking look at the new science that can track consciousness deep in the brain How does our brain generate a conscious thought? And why does so much of our knowledge remain unconscious? Thanks to clever psychological and brain-imaging experiments, scientists are closer to cracking this mystery than ever before. In this lively book, Stanislas Dehaene describes the pioneering work his lab and the labs of other cognitive neuroscientists worldwide have accomplished in defining, testing, and explaining the brain events behind a conscious state. We can now pin down the neurons that fire when a person reports becoming aware of a piece of information and understand the crucial role unconscious computations play in how we make decisions. The emerging theory enables a test of consciousness in animals, babies, and those with severe brain injuries. A joyous exploration of the mind and its thrilling complexities, Consciousness and the Brain will excite anyone interested in cutting-edge science and technology and the vast philosophical, personal, and ethical implications of finally quantifying consciousness.




Handbook of Sleep Research


Book Description

Handbook of Sleep Research, Volume 30, provides a comprehensive review of the current status of the neuroscience of sleep research. It begins with an overview of the neural, hormonal and genetic mechanisms of sleep and wake regulation before outlining the various proposed functions of sleep and the role it plays in plasticity, and in learning and memory. Finally, the book discusses disorders of sleep and waking, covering both lifestyle factors that cause disrupted sleep and psychiatric and neurological conditions that contribute to disorders. - Emphasizes a comparative and multidisciplinary approach to the topic of sleep - Covers the neurobiology and physiology of sleep stages, mechanisms of waking, and dreaming - Discusses in detail the proposed functions of sleep, from health and rest, to memory consolidation and synaptic plasticity - Examines the current state of research in mammalian and non-mammalian species, ranging from primates to invertebrates




Conn's Translational Neuroscience


Book Description

Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment




The Cambridge Handbook of Human Affective Neuroscience


Book Description

Neuroscientific research on emotion has developed dramatically over the past decade. The cognitive neuroscience of human emotion, which has emerged as the new and thriving area of 'affective neuroscience', is rapidly rendering existing overviews of the field obsolete. This handbook provides a comprehensive, up-to-date and authoritative survey of knowledge and topics investigated in this cutting-edge field. It covers a range of topics, from face and voice perception to pain and music, as well as social behaviors and decision making. The book considers and interrogates multiple research methods, among them brain imaging and physiology measurements, as well as methods used to evaluate behavior and genetics. Editors Jorge Armony and Patrik Vuilleumier have enlisted well-known and active researchers from more than twenty institutions across three continents, bringing geographic as well as methodological breadth to the collection. This timely volume will become a key reference work for researchers and students in the growing field of neuroscience.




The Caldron of Consciousness


Book Description

These new studies by prominent neuroscientists, psychologists and philosophers work toward a coherent framework for understanding emotion and its contribution to the functioning of consciousness in general, as an aspect of self-organizing, embodied subjects. Distinguishing consciousness from unconscious information processing hinges on the role of motivating emotions in all conscious modalities, and how emotional brain processes interact with those traditionally associated with cognitive function. Computationally registering/processing sensory signals (e.g. in the occipital lobe or area V4) by itself does not result in perceptual consciousness, which requires subcortical structures such as amygdala, hypothalamus, and brain stem. This interdisciplinary anthology attempts to understand the complexity of emotional intentionality; why the role of motivation in self-organizing processes is crucial in distinguishing conscious from unconscious processes; how emotions account for ‘agency’; and how an adequate approach to emotion-motivation can address the traditional mind-body problem through a holistic understanding of the conscious, behaving organism. (Series B)