Book Description
Neuropeptides and Brain Function
Author :
Publisher : Elsevier
Page : 363 pages
File Size : 20,32 MB
Release : 2011-09-22
Category : Medical
ISBN : 0080861970
Neuropeptides and Brain Function
Author : J.P.H. Burbach
Publisher : CRC Press
Page : 156 pages
File Size : 25,63 MB
Release : 1993-05-15
Category : Medical
ISBN : 9781850704539
Brain Functions of Neuropeptides contains capita selecta on neuropeptides by leading scientists in the neurosciences. As a guide through the wealth of neuropeptide research, the authors here present current and personal views on the roles that neuropeptide functions have in the nervous ystem, and their mode of action. The authors address an audience that includes readers at the undergraduate level in life sciences, but also experts who are intersted in timely issues.
Author : Y. H. Erlich
Publisher : Springer Science & Business Media
Page : 330 pages
File Size : 27,61 MB
Release : 2012-12-06
Category : Medical
ISBN : 1468435035
While neuroanatomy and neurophysiology were defining the unique features of the synapse as a site for cell to cell signaling in the late fifties, neurochemistry was establishing the identity and studying the biosynthetic pathways of monoamine neurotransmitters. Meanwhile, neuropsychiatry was keeping a vigilant eye on the outcome of this concerted effort with the untold hope that a genetic defect in neurotransmitter metabolism would ac count for the pathogenesis of certain psychiatric ill nesses. Thus, when neurochemists in the early sixties began to study the feasibility of measuring the metabolism of brain neurotransmitters in vivo, clinical biochemists eagerly adopted these methods to their needs and sought to verify whether inborn errors of transmitter biogenesis were a cause for at least certain forms of depression, mania and schizophrenia. Undoubtedly, it is still too early to evaluate the outcome of these studies. However, current opinion holds that gross inborn errors in transmitter metabolism do not anpear to be operative as a primary cause of psychia tric disorders. Though monoamine metabolism appears to be defective in certain groups of psychiatric disorders, the cause of these changes can at best be associated with changes in patterns of neuronal firing. It is generally believed that these persistent changes are determined by a number of unknown factors operative in various psychia tric illnesses. In the attempt to identify the molecular nature of these unknown factors, the focus of current research is directed toward transmitter receptors.
Author : John P. Bilezikian
Publisher : Academic Press
Page : 2074 pages
File Size : 44,90 MB
Release : 2008-09-29
Category : Medical
ISBN : 0080568750
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Author : Fred Nyberg
Publisher : CRC Press
Page : 321 pages
File Size : 21,9 MB
Release : 2012-06-19
Category : Medical
ISBN : 1439830622
Although the genomic era is no longer in its infancy, the life sciences are still facing questions about the role of endogenous proteins and peptides in homeostasis and pathologies. Delving into one of the most current fields of interest in biology and medicine, Neuropeptides in Neuroprotection and Neuroregeneration describes the impact of neuropeptides on neuroprotection and neuroregeneration. The book begins with chapters describing important features of the endogenous neuropeptide systems related to their formation, receptor signaling, and inactivation. It includes chapters focused on the design and development of peptide-like drugs (peptidomimetics). In addition, the book covers: General aspects regarding the biosynthesis, structures, and distribution of neuroactive peptides and their receptors Basic mechanisms for neuropeptide action, metabolism, as well as techniques for their detection and aspects essential for the cellular mechanisms underlying brain pathology Neuropeptides known for their impact in neurodegenerative and neuroprotective processes Fundamental aspects as well as recent progress in the development of peptidomimetics of neuroprotective and cognition-enhancing peptides
Author : Ernst Florey
Publisher : Manchester University Press
Page : 376 pages
File Size : 16,44 MB
Release : 1991
Category : Comparative neurobiology
ISBN : 9780719032981
Author : David de Wied
Publisher : Elsevier Publishing Company
Page : 428 pages
File Size : 44,4 MB
Release : 1990
Category : Medical
ISBN :
On the occasion of David de Wied's retirement as Professor of Pharmacology and Chairman of the Board of the Rudolf Magnus Institute, it was thought to be the appropriate moment to publish a volume reviewing the state-of-the-art concept on neuropeptide research. A major part of this research originated from De Wied, and the authors who contributed to the volume are all former or current associates. The volume begins with a classic article written by David de Wied in the late 1960's, which pointed the direction on which twenty years of multidisciplinary research could be based. Further chapters include aspects such as central neurohypophyseal hormone receptors and receptor mediated cellular responses, neuropeptides and behavioral adaptation: structure-activity relationships, neuro-opioid peptides and blood pressure control, neuropeptides and brain aging.
Author : Fleur L. Strand
Publisher : MIT Press
Page : 678 pages
File Size : 44,61 MB
Release : 1999
Category : Neuropeptides
ISBN : 9780262194075
This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.
Author : Richard E. Brown
Publisher : Cambridge University Press
Page : 434 pages
File Size : 16,2 MB
Release : 1994-01-27
Category : Science
ISBN : 9780521426657
This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
Author : S. Charles Schulz
Publisher : Oxford University Press
Page : 401 pages
File Size : 40,84 MB
Release : 2016-04-01
Category : Medical
ISBN : 019937807X
Schizophrenia and Psychotic Spectrum Disorders aims to engage young caregivers in psychiatry, psychology, nursing and social work so that they will be able to become well informed about this significant--and at times confusing--illness. Because schizophrenia is considered to be one of the most complicated and severe psychiatric disorders, this book has the goal of summarizing key issues of the illness, such as its presentation, frequency and age of onset, and diagnostic characteristics. It also contains informative chapters about the pathophysiology of schizophrenia, ranging from brain development issues, genetics, and likely abnormalities in neurotransmitters. This book will give young professionals and those joining the field an excellent and accessible background to treatment. In this area, Schizophrenia and Psychotic Spectrum Disorders provides a comprehensive approach to diagnosis, treatment initiation, strategies for non-response, approaches of therapy, and importantly, ways to provide family therapy and support.