Neuropsychological Function and Brain Imaging


Book Description

Over the past two decades researchers and clinicians in the neurosciences have witnessed a literal information explosion in the area of brain imaging and neuropsychological functioning. Until recently we could not view the nervous system except through the use of invasive procedures. Today, a variety of imaging techniques are available, but this technology has advanced so rapidly that it has been difficult for new information to be consolidated into a single source. The goal of this volume is to present information on technological advances along with current standards and techniques in the area of brain imaging and neuropsychological functioning. The quality of brain imaging techniques has improved dramatically. In 1975 one had to be content with a brain image that only offered a gross distinction between ventricular cavities, brain, and bone tissue. Current imaging techniques offer considerable precision and approximate gross neuroanatomy to such an extent that differentiation between brain nuclei, pathways, and white gray matter is possible. These technological advances have progressed so rapidly that basic and clinical research have lagged behind. It is not uncommon, particularly in longitudinal research, for the technical meth odology of a study to become obsolete while that study is still in progress. This has hampered certain aspects of systematic research and has also produced the need for a textbook that could address contemporary issues in brain imaging and neuropsychology.




Brain Imaging in Behavioral Medicine and Clinical Neuroscience


Book Description

Rapid developments in brain neuroimaging methods have occurred over the past decade. These advances have revolutionized cognitive and behavioral neuroscience, and are likely to have major influence on clinical psychological, psychiatric, and neurological practice over the coming years. There are a number of excellent books that focus on specific neuroimaging methods, such as fMRI. Furthermore, cognitive and neuroscience texts have increasingly incorporated functional brain neuroimaging. Yet, there are few books to date that consider and review emerging research in the application of brain neuroimaging methods for the study and assessment of behavioral and cognitive disorders. This book provides a broad coverage of current research trends in the clinical application of brain neuroimaging methods in the context of behavioral medicine, neuropsychology, and related areas of medical psychology. It uniquely integrates current neuroimaging methods and studies with current behavioral medicine research, and presents knowledge derived from recent developments in the fields of functional and structural brain imaging. By integrating information from experimental behavioral medicine with clinical insights, this book will serve as a source book for neuropsychologists, psychologists, neurologists, psychiatrists, and other professionals in both clinical practice and academic context. This integration results in the reader having a greater understanding of how the brain controls behavior, the disturbances of behavior that may occur with different disorders, and what clinicians should consider when assessing or working with patients with behavioral problems.




Mind and the Frontal Lobes


Book Description

In the past 25 years, the frontal lobes have dominated human neuroscience research. Functional neuroimaging studies have revealed their importance to brain networks involved in nearly every aspect of mental and cognitive functioning. Studies of patients with focal brain lesions have expanded on early case study evidence of behavioral, emotional, and cognitive changes associated with frontal lobe brain damage. The role of frontal lobe function and dysfunction in human development (in both children and older adults), psychiatric disorders, the dementias, and other brain diseases has also received rapidly increasing attention. In this useful text, 14 leading frontal lobe researchers review and synthesize the current state of knowledge on frontal lobe function, including structural and functional brain imaging, brain network analysis, aging and dementia, traumatic brain injury, rehabilitation, attention, memory, and consciousness. The book therefore provides a state-of-the-art account of research in this exciting area, and also highlights a number of new findings by some of the world's top researchers.




Fundamentals of Functional Brain Imaging


Book Description

This generously illustrated guide to functional imaging responds to the needs of non-specialists, professionals and students of psychology, cognitive neuroscience, psychiatry, behavioral neurology, and epistemology. It enables them to understand the basic principles of the highly specialized and constantly evolving imaging technologies and to assess for themselves the contribution of these technologies to their respective fields. Fundamentals of Functional Brain Imaging will be useful for practitioners and advanced students in psychology, cognitive neuroscience, and neuropsychology, residents in psychiatry and neurology, as well as the interested general public.




Comparative Neuropsychology and Brain Imaging


Book Description

This volume is a special commemorative publication in honor of Professor Dr. Ulrike Halsband, from the University of Freiburg in Germany, on the occasion of her 60th birthday, and includes chapters specially written for the volume, with recent views, reviews and results on such fields as functioneuroanatomytomy, neuropsychology, education, animal behavior, altered states of consciousness, hypnosis and the history of psychology in Germany. The contributors are internationally well-known scholars from academic and clinical institutions abroad in Europe. --




The Oxford Handbook of Functional Brain Imaging in Neuropsychology and Cognitive Neurosciences


Book Description

The Oxford Handbook of Functional Brain Imaging in Neuropsychology and Cognitive Neurosciences describes in a readily accessible manner the several functional neuroimaging methods and critically appraises their applications that today account for a large part of the contemporary cognitive neuroscience and neuropsychology literature. The complexity and the novelty of these methods often cloud appreciation of the methods' contributions and future promise. The Handbook begins with an overview of the basic concepts of functional brain imaging common to all methods, and proceeds with a description of each of them, namely magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), positron emission tomography (PET), diffusion tensor imaging (DTI), and transcranial magnetic stimulation (TMS). Its second part covers the various research applications of functional neuroimaging on issues like the function of the default mode network; the possibility and the utility of imaging of consciousness; the search for mnemonic traces of concepts; human will and decision-making; motor cognition; language; the mechanisms of affective states and pain; the presurgical mapping of the brain; and others. As such, the volume reviews the methods and their contributions to current research and comments on the degree to which they have enhanced our understanding of the relation between neurophysiological activity and sensory, motor, and cognitive functions. Moreover, it carefully considers realistic contributions of functional neuroimaging to future endeavors in cognitive neuroscience, medicine, and neuropsychology.




Fundamentals of Neural Network Modeling


Book Description

Provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. Over the past few years, computer modeling has become more prevalent in the clinical sciences as an alternative to traditional symbol-processing models. This book provides an introduction to the neural network modeling of complex cognitive and neuropsychological processes. It is intended to make the neural network approach accessible to practicing neuropsychologists, psychologists, neurologists, and psychiatrists. It will also be a useful resource for computer scientists, mathematicians, and interdisciplinary cognitive neuroscientists. The editors (in their introduction) and contributors explain the basic concepts behind modeling and avoid the use of high-level mathematics. The book is divided into four parts. Part I provides an extensive but basic overview of neural network modeling, including its history, present, and future trends. It also includes chapters on attention, memory, and primate studies. Part II discusses neural network models of behavioral states such as alcohol dependence, learned helplessness, depression, and waking and sleeping. Part III presents neural network models of neuropsychological tests such as the Wisconsin Card Sorting Task, the Tower of Hanoi, and the Stroop Test. Finally, part IV describes the application of neural network models to dementia: models of acetycholine and memory, verbal fluency, Parkinsons disease, and Alzheimer's disease. Contributors J. Wesson Ashford, Rajendra D. Badgaiyan, Jean P. Banquet, Yves Burnod, Nelson Butters, John Cardoso, Agnes S. Chan, Jean-Pierre Changeux, Kerry L. Coburn, Jonathan D. Cohen, Laurent Cohen, Jose L. Contreras-Vidal, Antonio R. Damasio, Hanna Damasio, Stanislas Dehaene, Martha J. Farah, Joaquin M. Fuster, Philippe Gaussier, Angelika Gissler, Dylan G. Harwood, Michael E. Hasselmo, J, Allan Hobson, Sam Leven, Daniel S. Levine, Debra L. Long, Roderick K. Mahurin, Raymond L. Ownby, Randolph W. Parks, Michael I. Posner, David P. Salmon, David Servan-Schreiber, Chantal E. Stern, Jeffrey P. Sutton, Lynette J. Tippett, Daniel Tranel, Bradley Wyble




The Organisation of Conceptual Knowledge in the Brain


Book Description

Category-specific knowledge disorders are among the most intriguing and perplexing syndromes in cognitive neuropsychology. The past decade has witnessed increased interest in these disorders, due largely to a heightened appreciation of the profound implications that an understanding of concept representation has for such diverse topics as object recognition, the organisation of the lexicon, and storage of long-term memories. Until recently, information about the representation of concepts was limited to findings from patients with brain injury and disease. This state of affairs has now changed with the advent and wide-spread availability of functional imaging for studying cognition in the normal human brain. The purpose of this special issue is to provide a forum for new findings and critical, theoretical analyses of existing data from patient and functional brain imaging studies. The contributions, all from major investigators in the field, range from studies of specific object categories such as animals, tools, fruit and vegetables, and faces, to the more general domains of number processing, social interaction, and mechanical knowledge. A unifying theme of these papers is the extent to which the findings can be best understood within the context of models that posit an innate, domain-specific organisation, those that appeal to an organisation by sensory- and motor-based features and properties, and those that propose an undifferentiated, distributed neural organisation.




The Role of Technology in Clinical Neuropsychology


Book Description

Neuropsychology as a field has been slow to embrace and exploit the potential offered by technology to either make the assessment process more efficient or to develop new capabilities that augment the assessment of cognition. The Role of Technology in Clinical Neuropsychology details current efforts to use technology to enhance cognitive assessment with an emphasis on developing expanded capabilities for clinical assessment. The first sections of the book provide an overview of current approaches to computerized assessment along with newer technologies to assess behavior. The next series of chapters explores the use of novel technologies and approaches in cognitive assessment as they relate to developments in telemedicine, mobile health, and remote monitoring including developing smart environments. While still largely office-based, health care is increasingly moving out of the office with an increased emphasis on connecting patients with providers, and providers with other providers, remotely. Chapters also address the use of technology to enhance cognitive rehabilitation by implementing conceptually-based games to teach cognitive strategies and virtual environments to measure outcomes. Next, the chapters explore the use of virtual reality and scenario-based assessment to capture critical aspects of performance not assessed by traditional means and the implementation of neurobiological metrics to enhance patient assessment. Chapters also address the use of imaging to better define cognitive skills and assessment methods along with the integration of cognitive assessment with imaging to define the functioning of brain networks. The final section of the book discusses the ethical and methodological considerations needed for adopting advanced technologies for neuropsychological assessment. Authored by numerous leading figures in the field of neuropsychology, this volume emphasizes the critical role that virtual environments, neuroimaging, and data analytics will play as clinical neuropsychology moves forward in the future.




Neuropsychology


Book Description

In this volume of the series Human Brain Function: Assessment and Rehabilitation we cover the area of how brain function is assessed with behavioral or neuropsycholog ical instruments. These assessments are typically conducted by clinical neuropsy chologists or behavioral neurologists, and so we made an effort to present the somewhat differing approaches to these two related disciplines. Clinical neuropsy chologists are psychologists who typically utilize standardized tests, while behav ioral neurologists are physicians who generally assess brain function as part of the clinical neurological evaluation. Both approaches have much to offer. The basic assumption of neuropsychological assessment is that the brain is the organ of behavior, and therefore, the condition of the brain may be evaluated with behavioral measures. Neuropsychological tests are those measures found by re search to be particularly sensitive to alterations in brain function. An adequate neuropsychological test is a procedure that can be related to some objective mea sure of alteration in brain function. Over the years, these objective measures have changed, but generally involve documentation through direct observation of brain tissue, or through histological, pathological, neuroimaging, or other laboratory procedures. The methods described in the first two volumes of this series describe the neuroimaging procedures that are often used in the validation of neuropsycho logical tests.