Book Description

Traumatic Brain Injuries (TBI) and Spinal Cord Injuries (SCI) can have long-term adverse effects on populations, including an increased risk of mortality, enduring disabilities and other long-term health problems. Both of these injuries affect large numbers of people, with between 250,000 and 500,000 people affected by a spinal cord injury every year, according to the WHO, and between 27 and 69 million people estimated to have been affected by a Traumatic Brain Injury worldwide. The effects of such injuries are far reaching and include loss of motor functions, impaired neurotransmission, neuroinflammation, apoptotic cell death (among others) and can cause persisting cognitive degradation and impairments. However, there exist a number of rehabilitative and regenerative processes and methods that help to restore motor functions and limit enduring disabilities within those affected by TBI and SCI, principally to facilitate neuroplasticity.