New Treatment Modalities in Rectal Cancer


Book Description

​This book provides an up-to-date and detailed overview of diagnostic and management strategies for rectal cancer. It includes chapters focusing on recent diagnostic modalities such as technical advances, the role of magnetic resonance imaging (MRI), immunology, and histopathology, as well as the latest surgical techniques for the management of rectal cancer. It also discusses the role of adjuvant, neo-adjuvant and non-operative approaches. Further, it presents the recent guidelines of prevention and early diagnosis, as well as current and future diagnostic and staging work-up, clearly and concisely, linking each topic to the therapeutic options arising from the staging. A large part of this multifaceted book is devoted to the in-hospital care of rectal cancer patients, from the fast-track procedures and enhanced recovery systems to detailed descriptions of the available surgical techniques, including salvage situations, accidents, complications and their treatment.




Rectal Cancer Treatment


Book Description

Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.




Modern Management of Cancer of the Rectum


Book Description

Modern Management of Cancer of the Rectum is intended to provide a comprehensive overview of all aspects of rectal neoplasms. It addresses epidemiology, biology, screening and chemoprevention, the role of imaging in diagnosis, staging and prognosis, radiation therapy, medical and surgical treatment, as well as new modalities of therapy, including laparoscopy, and transanal endoscopic surgery. A greater understanding of prognostic factors, patterns of spread and natural history has occurred during the past decade; together with new diagnostic modalities this has led to significant changes in the management of patients with rectal cancer. This book will be invaluable for all those who treat rectal cancer.




Holland-Frei Cancer Medicine


Book Description

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates




Rectal Cancer


Book Description

Despite lifestyle improvements, the incidence of rectal cancer is increasing in industrialised countries. Rapid advances in technology, growing knowledge of the biological history of the disease and closer attention to patients' quality of life after surgery have led to a less invasive approach. In the last 15 years, the surgical approach has shifted from extended resection to sphincter-saving procedures, featuring a multidisciplinary approach and a high level of specialisation. The experienced surgeon can plan and choose the "right treatment for the right patient" only with the support of the radiologist, endoscopist and pathologist (preoperative staging), oncologist and radiotherapist (neoadjuvant therapy), and psychologist and stomatherapist (rehabilitation). In addition, the difficult problems of salvage procedure and the reconstruction of anal sphincter after abdominal resection are explored. The aim of this book is to clarify the rapid advances and to offer guidelines for doctors dealing with rectal cancer. Taking into account indications, contraindications, risks, benefits and controversies, the authors offer clear and practice-oriented answers for a wide range of specialists and experts, as well as those new to the field.




Surgical Treatment


Book Description




Colon and Rectal Cancer


Book Description

Colorectal cancer is the fourth most common type of cancer worldwide yet there continues to be controversy and confusion regarding the best methods and techniques for its diagnosis and management. Colon and Rectal Cancer is a clinician’s guide to major advances, including the tremendous improvements in endorectal ultrasonography, which allow a much more accurate staging of rectal tumors and surrounding lymph nodes. In addition, this comprehensive manual investigates the increasing variety of treatment options for rectal cancers at differing stages. Individual chapters address such topics as: Colon and rectal polyps Screening for colon and rectal cancer Presentation and pretreatment evaluation of patients with adenocarcinoma of the colon Treatment of both colon and rectal cancers and their follow-up after treatment Neoadjuvant and adjuvant therapy for adenocarcinoma of the rectum Treatment for metastatic disease of the colon and rectum Uncommon tumors of the colon and rectum Assembled with the practicing health professional in mind, this clearly written reference will be useful to any practitioner who encounters patients suffering from these malignancies. By fully and objectively evaluating the utility and value of all pretreatment and posttreatment studies, Colon and Rectal Cancer will guide practitioners through the responsible assessment of staging, follow-up studies, and treatment modalities for those suffering from cancers of the colon and rectum.




Recent Advances in the Treatment of Colorectal Cancer


Book Description

This book examines the latest indications and techniques for various endoscopic and surgical colorectal cancer treatments, discussing not only on the standard lymph node dissection technique, but also on laparoscopic and robotic surgery. It particularly focuses on the treatment of rectal cancer, with chapters on radiation therapy and sphincter preservation, which is analyzed from Asian perspectives that differ from those of Western treatment. Further, it presents the results of combining chemotherapy and oral drugs, as well as the treatment of hereditary cancer using next-generation sequencing for genetic diagnosis. Edited by surgeons who have pioneered the research and treatment of colorectal cancer, Recent Advances in the Treatment of Colorectal Cancer presents extensive information for clinicians such as endoscopic surgeons, colorectal surgeons, as well as oncologists and researchers specializing in this field. Providing a foundation for new ideas, it enables advanced surgeons to further develop their skills and offers thought-provoking, instructive and informative reading for residents, students and medical staff.




Cancers of the Colon and Rectum


Book Description

This text provides information currently not available from any single source. It summarizes state-of-the-art issues related to the treatment of colorectal cancer including descriptions of optimal multidisciplinary care utilizing all available modalities as well as related issues such as screening and prevention, management for special populations, psychological support and emerging directions in future treatment. Over the course of the last decade, the treatment of colorectal cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of colorectal cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues including genetics, radiology, surgery, molecular diagnostics, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment.




Rectal Cancer


Book Description

Colorectal cancer, a formidable adversary within the landscape of oncology, remains a significant global health challenge. Afflicting millions worldwide, its impact reverberates through communities, families, and healthcare systems alike. Yet, amidst the complexity and gravity of this disease, there exists a beacon of hope rooted in understanding, prevention, and treatment. At its core, colorectal cancer arises from the malignant transformation of cells lining the colon or rectum, typically progressing from benign polyps to invasive tumors over time. While its exact etiology remains multifaceted, a culmination of genetic predispositions, lifestyle factors, and environmental influences underscores its pathogenesis. Understanding these intricacies is pivotal in our quest to combat this disease effectively. Exploring the epidemiology of colorectal cancer unveils a sobering reality. Globally, it ranks as the third most commonly diagnosed cancer in men and the second in women, with over 1.9 million new cases reported annually. Within this statistical narrative lies a tale of disparities, with incidence rates varying widely across regions and populations. From the bustling cities of developed nations to the remote villages of underserved communities, no corner of the world is untouched by its reach. Yet, amidst this daunting landscape, lies a beacon of hope: prevention. Research has illuminated the profound impact of lifestyle modifications and early detection strategies in mitigating the burden of colorectal cancer. From dietary interventions promoting fiber-rich foods and the reduction of processed meats to the implementation of robust screening programs, opportunities abound to shift the tide in our favor. Indeed, the cornerstone of our defense against colorectal cancer lies in our ability to arm ourselves with knowledge and awareness. Through public health initiatives, advocacy campaigns, and educational outreach, we empower individuals to take proactive steps in safeguarding their health. From the corridors of research institutions to the halls of community centers, collaboration emerges as our greatest ally in this endeavor. As we delve deeper into the labyrinth of colorectal cancer, we uncover a myriad of treatment modalities aimed at eradicating the disease and improving patient outcomes. From surgical interventions offering curative intent to the advent of targeted therapies and immunomodulatory agents, innovation propels us forward on the frontlines of battle. Yet, amidst these triumphs, challenges persist, underscoring the need for continued research, advocacy, and investment in cancer care.