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Mimicking the Extracellular Matrix

Author : Gregory H. Hudalla

Publisher : Royal Society of Chemistry

Page : 422 pages

File Size : 24,20 MB

Release : 2015-11-18

Category : Medical

ISBN : 1849738335

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Book Description

Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.



Biotechnology

Author : Reda Sammour

Publisher : IntechOpen

Page : 0 pages

File Size : 15,80 MB

Release : 2012-03-14

Category : Science

ISBN : 9789535101512

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Book Description

This book deals with the importance of application of molecular biology as an approach of biotechnology for improvement of the quality of human life. One of the interesting topics in this field, is the identification of the organisms that produce bioactive secondary metabolites. It also discusses how to structure a plan for use and preservation of those species that represent a potential source for new drug development, especially those obtained from bacteria. The book also introduces some novel applications of biotechnology, such as therapeutic applications of electroporation, improving quality and microbial safety of fresh-cut vegetables, producing synthetic PEG hydro gels to be used as an extra cellular matrix mimics for tissue engineering applications, and other interesting applications.





Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Author : Mario Barbosa

Publisher : Woodhead Publishing

Page : 392 pages

File Size : 18,17 MB

Release : 2017-09-25

Category : Technology & Engineering

ISBN : 008100852X

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Book Description

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers



Extracellular Matrix in Development

Author : Douglas W. DeSimone

Publisher : Springer Science & Business Media

Page : 260 pages

File Size : 50,61 MB

Release : 2013-03-15

Category : Science

ISBN : 3642359353

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Book Description

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.







Engineering Neural Tissue from Stem Cells

Author : Stephanie Willerth

Publisher : Academic Press

Page : 226 pages

File Size : 19,22 MB

Release : 2017-07-05

Category : Technology & Engineering

ISBN : 0128113863

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Book Description

Engineering Neural Tissue from Stem Cells covers the basic knowledge needed to understand the nervous system and how existing cells can be used to create neural tissue. This book presents a broad range of topics related to the design requirements for engineering neural tissue from stem cells. It begins with the anatomy and function of the central and peripheral nervous system, also covering stem cells, their relation to the nervous system and their function in recovery after injury or disease. In addition, the book explores the role of the extracellular matrix and vasculature/immune system and biomaterials, including their suitability for neural tissue engineering applications. Provides readers entering the field with a strong basis of neural tissue engineering processes and real-world applications Discusses the most current clinical trials and their importance of treating nervous system disorders Reviews the structure and immune response of the nervous system, including the brain, spinal cord and their present cells Offers a necessary overview of the natural and synthetic biomaterials used to engineer neural tissue