Pharmacology and Nutritional Intervention in the Treatment of Disease


Book Description

Pharmacology and Nutritional Intervention in the Treatment of Disease is a book dealing with an important research field that has worldwide significance. Its aim is to strengthen the research base of this field of investigation as it yields knowledge that has important implications for biomedicine, public health and biotechnology. The book has brought together an interdisciplinary group of contributors and prominent scholars from different parts of the world. The basic purpose of this book was to promote interaction and discussion of problems of mutual interests among people in related fields everywhere. The main subjects of the book include nutrition, mechanisms underlying treatments, physiological aspects of vitamins and trace elements, antioxidants: regulation, signalling, infection and inflammation, and degenerative and chronic diseases.




Pharma-Nutrition


Book Description

Natural products and functional/medical foods are now widely acknowledged as having an effect on the microbiome of the intestine, which in turn influences the outcome of certain disease. This book reviews the impact and effects of natural products and functional/medical foods (nutritional programming) on disease management, specifically focusing on diseases related to 1) Inflammation and Immunity, 2) Cancer, COPD and Cachexia, 3) Allergy and 4) Brain Neuro/Immune. Hippocrates said "let medicine be thy food and food be thy medicine". While most of us are familiar with Hippocrates famous words, we admit that in recent times, the disciplines of pharma and nutrition have evolved separately. Today, with the ever growing burden of diseases in modern society, we see a convergence of the two in relation to specific disease prevention and treatment. This re-discovered common ground between the complementary values of pharma and nutrition can be conceptualized in the term pharma-nutrition. Various chapters in the book review the aspects of molecular characteristics of food ingredients towards clinical effectiveness and relevance.







At the Crossroads Between Nutrition and Pharmacology


Book Description

Functional foods (foods with known bioactive properties) have shown potential for preventive and therapeutic treatments. However, this potential must be safely determined before they enter the commercial market. At the same time, nutrition research is transforming into a data driven field with reference to the identification and development of functional food products due to the large number of variables affecting food biochemistry in the human body. This volume presents reviews of recent advances in food chemistry, food technology and nutraceutical research (for diet therapy and cosmetics). Chapters in this volume cover a broad spectrum of topics: - drug discovery and development in the modern nutraceutical industry, - recent developments in the extraction, identification and quantification of bioactive peptides in foods, - concepts of bioavailability, bioaccessibility, bioactivity, bioefficiency and bioconversion of bioactive foods, - synthetic routes for obtaining bioactive compounds, - the role of nutrigenomics to identify key cellular functions by specific genetic and epigenetic interactions with a nutrient, - anti-cancer properties of important bioactive components of medicinal plants, - the effect of a diet based on different bioactive foods on prevention and treatment of diabetes, - antioxidant effects on cardiovascular disease, - beneficial effects of bioactive foods on metabolic syndrome, - the potential of tauroursodeoxycholic acid on prevention and recovery of neurodegenerative diseases, - the effects of natural phytochemicals in prostate cancer, - the effects of methylxanthines (caffeine and others), and culinary methods on physiological and toxicological effects of the bioactive food constituents. The volume is an ideal reference for pharmacy students, nutritionists, healthcare providers and nutraceutical R&D specialists interested in functional foods. [Series Intro] Frontiers in Bioactive Compounds brings edited reviews on the analysis and characterization of natural compounds of medicinal interest. Each volume covers useful information on a variety of natural sources as well as analytical techniques. This series is essential reading for analytical and medicinal chemists as well as professionals involved in natural and pharmaceutical product research and development.







Drug-nutrient Interrelationships


Book Description




Human Health: Nutrition and Pharmacology


Book Description

Human health refers to the total state of social, physical as well as mental well-being rather than just the absence of illness, infirmity or disease. Nutrients are components found in food that drive biological activity and are therefore necessary for human health. Good nutrition is required for a person to develop physically and maintain proper health. Nutrients can be classified as carbohydrates, proteins, minerals, lipids as well as vitamins, which are helpful in performing essential functions of the body. They are helpful in growth and maintenance of body parts like teeth, bone and muscle, as well as the generation of energy. Nutrition also has a significant impact on the safety, metabolism and effectiveness of a drug. The interactions between food and drugs are studied within pharmacology under the sub-discipline of nutritional pharmacology. It also studies the effect of different micronutrients on the pharmacodynamics and pharmacokinetics of drugs. This book explores all the important aspects of pharmacology and nutrition in the modern day. It aims to shed light on the role of nutrition and pharmacology in human health. Researchers and students in this field will be assisted by this book.










Nutrition and Drugs


Book Description

Abstract: Thirteen authoritative review articles for physicians, nutritionists, and graduate students discuss thecurrent understanding of how certain drugs used for therapeutic purposes affect the transport, absorption, and metabolism of important dietary nutrients. Chapter topics include drug-vitamin B6 interaction; vitamin D metabolism and metabolic bone disease; vitamin B12 and folate metabolism; vitamin A analogs in skin disorders; protein nutrition in alcoholic liver damage; lipid metabolism in cases of lipid-lowering drugs and low-fat diets; and carbohydrate metabolism in the case of the effect of sulfonylurea drugs on insulin resistance and insulin-receptor function. Other general aspects of drug nutrition interaction are addressed in chapters on cellular transport; drugs in the food supply; nutrient aborption; appetite regulation; and combined drugs and diet therapy. A discussion of the use of diuretics and salt restriction in blood pressure control also is included. (wz).