Obesity as a Common Denominator in Breast Cancer and Cardiovascular Disease


Book Description

Obesity is widely regarded as a shared, modifiable risk factor of both breast cancer (BC) and cardiovascular disease (CVD). Human epidermal growth factor receptor 2 (HER2)-positive BC displays very aggressive behavior, and can be effectively treated with targeted therapies and chemotherapy regimens, though such treatments can induce cardiotoxicity. While the main research efforts are appropriately focused on the management of BC and heart failure (HF), obesity and its metabolic consequences, which are often linked with both these conditions, often remain unaddressed. This book combines a very practical approach, grounded in medical research, to these interconnected medical problems, in order to bridge the gap between current guidelines and clinical practice. It will serve to educate medical team members, such as oncologists, cardiologists, primary care physicians, and nurses, on cardioprotection, and moderate weight reduction. It highlights a need for the balanced integration of modern treatments of BC and HF, with healthy nutrition, regular physical activity, and helpful strategies to cope with chronic stress. In addition, the book represents a supportive resource for BC patients or survivors, who wish to be actively engaged in their long-term therapy journey.




Obesity as a Common Denominator in Breast Cancer and Cardiovascular Disease


Book Description

Obesity is widely regarded as a shared, modifiable risk factor of both breast cancer (BC) and cardiovascular disease (CVD). Human epidermal growth factor receptor 2 (HER2)-positive BC displays very aggressive behavior, and can be effectively treated with targeted therapies and chemotherapy regimens, though such treatments can induce cardiotoxicity. While the main research efforts are appropriately focused on the management of BC and heart failure (HF), obesity and its metabolic consequences, which are often linked with both these conditions, often remain unaddressed. This book combines a very practical approach, grounded in medical research, to these interconnected medical problems, in order to bridge the gap between current guidelines and clinical practice. It will serve to educate medical team members, such as oncologists, cardiologists, primary care physicians, and nurses, on cardioprotection, and moderate weight reduction. It highlights a need for the balanced integration of modern treatments of BC and HF, with healthy nutrition, regular physical activity, and helpful strategies to cope with chronic stress. In addition, the book represents a supportive resource for BC patients or survivors, who wish to be actively engaged in their long-term therapy journey.




Global Health Complications of Obesity


Book Description

Global Health Complications of Obesity presents a valuable resource for research scientists and clinicians by covering the burden of obesity and related diseases and serving as a starting point for in-depth discussions in academic settings and for obesity-treatment specialists. Obesity is associated with a statistically higher risk of heart disease, hypertension, insulin resistance, type 2 diabetes and many other diseases. This succinct resource focuses on the current data, research and management of obesity. It is essential reading for healthcare professionals, endocrinologists, nutritionists, public health students and medical students. - Presents clinical cases, key terms and targeted references - Addresses diseases including diabetes, cancer, hypertension, osteoarthritis, fatty liver disease, infertility, renal failure and depression - Provides a link to new knowledge that is ideal for both researchers and clinicians




Medical Biochemistry - E-Book


Book Description

Written by carefully selected global experts, practicing physicians, and educators in the various sub-disciplines of biochemistry, Medical Biochemistry, 6th Edition, offers a unique combination of research and clinical practice tailored to today's integrated courses. Covering clinically relevant topics in greater detail than other texts, this outstanding resource provides a strong overview of traditional areas in medical biochemistry along with state-of-the-art coverage of today's latest developments. You'll learn basic science concepts alongside clinical cases that describe patients likely to be encountered in clinical training, as well as how to use laboratory tests to diagnose and monitor the most important conditions. Thorough yet accessible, this clinically focused text is useful from medical school to clinical practice. - Features a strong clinical orientation, emphasizing the relevance of biochemistry to the daily practice of medicine. - Highlights the latest developments in regulatory and molecular biology, signal transduction, age-related chronic disease, epigenetics, and bioinformatics and the "-omics, as well as important global medical issues such as diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and nutrition and exercise. - Emphasizes clinical evaluation, maintenance of good health, and disease prevention, as well as translational medicine and the diagnosis and treatment of disease. - Contains organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused chapters on the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer. - Includes clear, colorful icons and illustrations that help you easily navigate the text and understand the material. - Provides online features such as challenging "Active Learning questions for independent study, relevant websites that reinforce or supplement chapter content, 150+ multiple-choice and USMLE-style questions, a quick-reference glossary, additional images and case studies, references to current literature, and more.




Medical Biochemistry


Book Description

Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the ‘–omics’. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine. Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today’s integrated courses. Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today's integrated courses. Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer




The Toxic Microbiome


Book Description

Gut microbiomes are dynamic communities varying from population to population and throughout life. In Western societies, a toxic metabolic shift of gut microbiomes is a driver and underestimated risk factor for the development of many noncommunicable chronic pathologies. This book identifies the root cause of these deleterious microbial changes. During the last several decades, increased consumption of animal products, coinciding and correlating with global climate change, has been a contributing cause of undesirable gut microbiome changes. Key Features Establishes a connection between poor gut microbiome health and chronic disease and cancer development Demonstrates how animal products and low-fiber diet patterns induce a detrimental metabolic transition of the gut microbiome from a human health-maintaining towards a disease-promoting state Discusses the opportunity of a toxic microbial metabolic signature as a powerful clinical and diagnostic tool to effectively predict chronic disease and cancer development Provides the latest evidence on different strategies to rebuild a healthy microbiome metabolism and effectively prevent noncommunicable diseases and colorectal cancer Documents the gut microbiome benefits of a plant-based diet




The Real Secret to Optimal Health


Book Description

World renowned sports medicine physician Dr. Anthony Galea reveals the secret to optimum mental and physical health. With Dr. Galea's background in science he helps the reader understand how their body works and how to reach its full potential. You will learn How to turn back the age clock by understanding how spirituality, diet, and exercise all work together to create the perfect working machine What star athletes such as Tiger Woods, A-Rod, or the Olympic athletes follow in their diet and exercise How to balance your blood chemistry and hormone levels Why diets fail How to develop a perfect eating plan that's easy to follow, effective, and won't leave you feeling hungry What foods that have a positive effect on your body and those you should avoid Exercises you can begin at any fitness level and will only take minutes a day to follow Causes and treatments of common injuries How 10 minutes of meditation a will help give you a more youthful appearance




Prevent and Reverse Heart Disease


Book Description

The New York Times bestselling guide to the lifesaving diet that can both prevent and help reverse the effects of heart disease Based on the groundbreaking results of his twenty-year nutritional study, Prevent and Reverse Heart Disease by Dr. Caldwell Esselstyn illustrates that a plant-based, oil-free diet can not only prevent the progression of heart disease but can also reverse its effects. Dr. Esselstyn is an internationally known surgeon, researcher and former clinician at the Cleveland Clinic and a featured expert in the acclaimed documentary Forks Over Knives. Prevent and Reverse Heart Disease has helped thousands across the country, and is the book behind Bill Clinton’s life-changing vegan diet. The proof lies in the incredible outcomes for patients who have followed Dr. Esselstyn's program, including a number of patients in his original study who had been told by their cardiologists that they had less than a year to live. Within months of starting the program, all Dr. Esselstyn’s patients began to improve dramatically, and twenty years later, they remain free of symptoms. Complete with more than 150 delicious recipes perfect for a plant-based diet, the national bestseller Prevent and Reverse Heart Disease explains the science behind the simple plan that has drastically changed the lives of heart disease patients forever. It will empower readers and give them the tools to take control of their heart health.







The Doctor's Guide to Weight Loss Surgery


Book Description

Whether you’re already planning to have weight-loss surgery or are still trying to decide, here is what you need to know about the operation that could save your life If you are considering weight-loss surgery, you are not alone. Obesity is the most common chronic disease in the U.S. today, affecting one out of every four Americans. In this indispensable resource, Dr. Louis Flancbaum, one of the world’s foremost experts on weight-loss surgery, takes you through the entire process, from presurgical evaluation to postop care. You’ll find everything you need to know to get the most out of the latest groundbreaking procedures available that can radically improve your health--and your quality of life. You’ll discover: • Why WLS is the safest treatment for patients with clinically severe or morbid obesity • How to determine if you’re a candidate for WLS • What to look for when choosing a surgeon • How to choose the surgical procedure that’s right for you • What to expect pre-, peri-, and postsurgery • Common side effects and what they can mean for you • Diet and nutritional guidelines after WLS Plus: what to do if your insurance policy excludes obesity treatment, how to determine when you can resume normal activities and return to work, healthful recipes, patient success stories, support groups . . . and much more Including detailed charts and tables, helpful resources, and websites, this is the only sourcebook on weight-loss surgery you’ll ever need.