Occupational Neurotoxicology


Book Description

Many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses: Neurotoxic agents commonly encountered in the workplace Signs and symptoms of neurotoxicity and of the factors affecting neurotoxic effects Biological monitoring and the use of biomarkers Epidemiological methods and clinical approaches to occupational neurotoxicology The analysis of behavioral, electrophysiological, and imaging techniques in the diagnosis of neurotoxicity Occupational neurotoxicity in developing countries The evaluation and management of occupational illnesses due to neurotoxicity Occupational Neurotoxicology concisely covers important facts on the adverse effects of chemical, biological, and physical agents that can impair or alter the structure of the nervous system. Professionals and researchers in the fields of occupational medicine, toxicology, epidemiology, neurology, industrial hygiene, and psychology will all find relevant information on the health problems that can occur from exposure to neurotoxicants.




Environmental Neurotoxicology


Book Description

Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.




Occupational Toxicology


Book Description

Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment.




Occupational and Environmental Neurotoxicology


Book Description

ritten by a noted expert in occupational and environmental medicine and neurology, this volume offers clinicians much-needed guidance in diagnosing and treating neurologic disorders caused by chemical exposure. The book delineates the key symptoms, presents an approach to assessing exposed individuals, and provides clinically relevant information on the twenty major occupational and environmental neurotoxicants. Discussions of the neurotoxic agents follow a consistent, user-friendly format. Dr. Feldman briefly describes the physical nature and chemical structure of each substance and its sources of exposure, recommended exposure limits, and metabolism. He then details the symptoms and physical findings associated with the substance, the most useful confirmatory diagnostic tests, and the most appropriate therapeutic and preventive measures. Finally, he presents case histories and discusses the acute and long-term risks of various exposure scenarios




Behavioral Measures of Neurotoxicity


Book Description

Exposure to toxic chemicalsâ€"in the workplace and at homeâ€"is increasing every day. Human behavior can be affected by such exposure and can give important clues that a person or population is in danger. If we can understand the mechanisms of these changes, we can develop better ways of testing for toxic chemical exposure and, most important, better prevention programs. This volume explores the emerging field of neurobehavioral toxicology and the potential of behavior studies as a noninvasive and economical means for risk assessment and monitoring. Pioneers in this field explore its promise for detecting environmental toxins, protecting us from exposure, and treating those who are exposed.




Occupational Toxicology, Second Edition


Book Description

Hazardous agents are an ongoing concern in the modern workplace, with many examples of workers being severely affected by chemicals as a result of both acute and chronic exposure. Occupational Toxicology, 2nd Edition introduces the basics of toxicology that underpin the application of toxicological information to the workplace environment. The book contains chapters on the most important workplace exposures such as metals, pesticides, solvents, plastics, gases, and particulate matter, as well as the organs likely to be affected. The lungs and the skin are given individual consideration as common sites of injury and disease caused by exposure to chemicals. Genotoxicity and cancer are also singled out for particular attention due to ongoing concern about cancer-related effects of chemicals. Important fields interfacing with occupational toxicology - hygiene, epidemiology, and occupational medicine - are also covered to assist the reader in understanding the necessity of cross-discipline considerations in dealing with workplace exposures. This practical approach makes this book particularly valuable to students of toxicology as well as to occupational health and safety professionals at all levels.




Neurotoxicology


Book Description

Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. - Discusses neurobehavioral testing methods for assessment of neural dysfunctions - Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems - Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity - Presents step-by-step procedures for many methods - Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation




Occupational Diseases in the Construction Industry


Book Description

Despite occupational diseases in construction contributing to a significant proportion of fatalities, and permanent and temporary incapacities, they have not gained as much attention as occupational injuries from practitioners and researchers. The research in this book aims to discover occupational diseases that cause fatalities and permanent and temporary incapacities in the construction industry, along with their epidemiological causal mechanisms. Through chapters examining cancers, circulatory system diseases, respiratory system diseases, nervous system and sense organ diseases, and musculoskeletal diseases, the authors provide new knowledge and insights to help proactively prevent and control these diseases. The research underpinning the development of the book applies empirical analyses of real-world occupational disease data for the construction industry alongside a detailed review and meta-analysis of literature pertinent to risk factors and methods and strategies to prevent and/or control occupational diseases in construction. Knowing the riskiest diseases and occupations for construction workers, along with organisational and personal risk factors, is critical to optimising risk management efforts. This book should be of interest to students, researchers, and practitioners in construction management, occupational health and safety, and risk management.




Occupational Neurotoxicology


Book Description

Occupational Neurotoxicology, Volume Seven covers neurotoxicants and exposures to a variety of hazards in the workplace and how they can affect nervous functions in different ways. Metals and organic compounds, both at high level acute exposure and long-term low-level exposure can affect motor functions, cognition, behavior and neurosensory functions. Sections cover Oil leakage in aircraft, aerotoxic syndrome, Organic solvents, WTC neurotoxicities, Environmental intolerance, Pesticides, Carbon monoxide, Mercury Neurotoxicity in Gold Miners, and the Current evolution of neurobehavioral methods. - Provides updated information about exposure and neurotoxic outcomes - Includes indication on new tools for neurobehavioral assessment - Covers practical indications on preventive aspects




Occupational and Environmental Neurology


Book Description

Occupational and Environmental Neurology fills a gap in the clinical literature available to the neurologist and occupational medicine physician. This volume meets a critical need for clinical guidelines for determination of whether neurological dysfunction in a worker is caused by a naturally occurring condition or is secondary to local exogenous working conditions. The textbook originated as a course at the annual meeting of the American Academy of Neurology and has been developed into an important resource in this rapidly evolving field of medicine. A readable reference, the book is written by academic clinical neurologists with experience in occupational medicine. The authors discuss typical neurological problems, including movement disorders and peripheral neuropathy, traumatic head and spinal cord injuries, cumulative trauma disorders, neurological dysfunctions unique to performing artists, and the neuroepidemiology of some naturally occurring disorders linked to work place exposure. - Occupational and Environmental Neurology