Immune Response and the Eye


Book Description

In memory of J. Wayne Streilein, the pioneer in ocular immunology The second edition of Immune Response and the Eye' highlights recent insights into the dangerous compromise' between the immune system and the eye, which protects the eye against pathogens while limiting inflammation and immune-mediated injury to ocular tissues with little or no regenerative potential. It discusses the broad spectrum of physiological, immunological, anatomical, and biochemical adaptations that conspire to closely regulate the tone and tenor of immune responses in the eye. This volume further describes immune-mediated diseases that occur when the compromise between the immune system and the eye is breached. This breakdown in immune privilege threatens the vision of millions each year. Finally, recent advances in ocular immunology are presented, which offer potential therapeutic applications in corneal and retinal transplantation and in the management of blinding autoimmune diseases of the eye. Eye researchers, ophthalmologists and immunologists will appreciate the state-of-the-art and authoritative information presented in Immune Response and the Eye'




Diagnosis & Treatment of Uveitis


Book Description

Uveitis is inflammation of the middle layer of the eye, which is known as the uvea or uveal tract. It is a complex condition with a variety of causes and clinical manifestations, including injury, infection or an underlying condition. This 1200pp second edition brings ophthalmologists fully up to date with the latest developments in diagnosing and treating uveitis. Beginning with the basic principles of the disease, its diagnosis and management, the following sections discuss the treatment of numerous different infectious, non infectious, masquerade and autoimmune syndromes. Basic science, differential diagnosis, pathology and clinical management are discussed for each condition. Written by specialists from the Massachusetts Eye Research and Surgery Institution (MERSI) and John A Moran Eye Center in the USA, this comprehensive new edition includes 699 colour images and illustrations. Key points Comprehensive, second edition bringing ophthalmologists fully up to date with diagnosis and treatment of uveitis Discusses different uveitis syndromes – infectious, non infectious, masquerade and autoimmune Authored by US ophthalmic specialists Includes 699 full colour images and illustrations First edition published in 2001 by Saunders




Ocular Immunology in Health and Disease


Book Description

Provides detailed information about ocular immunity and the basis of ocular immune privilege, and elaborates on the role of immune effector mechanisms in specific ocular conditions. Offers a detailed overview of immune system function, discusses autoimmune diseases and allergic conditions affecting the eye and their treatment, reviews the immunology of corneal graft rejection, and discusses the immune system's role in ocular tumor elimination and corneal transplant. Annotation copyrighted by Book News, Inc., Portland, OR




Diagnostic Criteria in Autoimmune Diseases


Book Description

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.




The Eye


Book Description

The Eye: Basic Sciences in Practice provides highly accessible, concise coverage of all the essential basic science required by today's ophthalmologists and optometrists in training. It is also essential reading for those embarking on a career in visual and ophthalmic science, as well as an invaluable, current refresher for the range of practitioners working in this area. This new fourth edition has now been fully revised and updated in line with current curricula, key research developments and clinical best practice. It succinctly incorporates the massive strides being made by genetics and functional genomics based on the Human Genome Project, the new understanding of how the microbiome affects all aspects of immunology, the remarkable progress in imaging technology now applied to anatomy and neurophysiology, as well as exciting new molecular and other diagnostic methodologies now being used in microbiology and pathology. All this and more collectively brings a wealth of new knowledge to students and practitioners in the fields of ophthalmology and visual science. For the first time, this (print) edition also now comes with bonus access to the complete, fully searchable electronic text - including carefully selected additional information and new video content to further explain and expand on key concepts - making The Eye a more flexible, comprehensive and engaging learning package than ever before. The only all-embracing textbook of basic science suitable for trainee ophthalmologists, optometrists and vision scientists - other books concentrate on the individual areas such as anatomy. Attractive page design with clear, colour diagrams and text boxes make this a much more accessible book to learn from than many postgraduate textbooks. Presents in a readable form an account of all the basic sciences necessary for an understanding of the eye - anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology. More on molecular pathology. Thorough updating of the sections on pathology, immunology, pharmacology and immunology. Revision of all other chapters. More colour illustrations Comes with complete electronic version




Animal Models of Ophthalmic Diseases


Book Description

This book describes experimental animal models that mimic common human ocular diseases: herpetic keratitis, cataract, glaucoma, age-related macular degeneration, diabetic retinopathy, uveitis, retinitis pigmentosa, Graves’ disease, and intraocular tumors. In conjunction, these models reflect the diversity and utility of tools used to study human disease. World expert clinicians discuss each model based on their clinical experience and the text is supported by numerous photos and diagrams. In describing the most pertinent animal models of ophthalmic diseases, this book will be of interest to ophthalmologists, vision researchers, fellows, residents and medical students.




Whitcup and Nussenblatt's Uveitis


Book Description

Comprehensive and readable, Whitcup and Nussenblatt's Uveitis, 5th Edition, covers every aspect of this complex subspecialty in a single convenient volume. This clinically relevant guide covers the medical, pharmacological, and surgical treatment of uveitis in a visually rich, full-color format, offering a complete overview for today's clinicians. New and updated case studies, key points boxes, and more than 400 images and graphics highlight major clinical points and provide insight into real situations that you can apply in practice. - Features multiple chapters on diagnostic approach to help you meet the challenge of making accurate diagnoses. - Reflects advancements and new developments on all aspects of uveitis including new medical and surgical treatments. - Covers key topics such as the use of PCR in diagnostic testing, cataract surgery in patients with uveitis, the use of OCT in diagnosis and treatment, new infectious causes of uveitis (including Zika and Ebola), and novel treatments for inflammatory eye disease. - Includes new clinical photographs, illustrations, and OCT images throughout. - Reviews new randomized clinical trials of new uveitis therapy, as well as the approach to patients with HIV and HIV-associated ocular diseases including CMV retinitis and immune recovery uveitis. - Provides expanded information on masquerade syndromes with important tips on diagnosis and management of intraocular lymphoma.




Uveitis


Book Description

This new edition expands on the diagnostic and therapeutic approaches to uveitis. New fluorescein angiograms and indocyanine angiograms are presented, and descriptive case studies provide examples relevant to the treatment of patients with uveitis. Now with 79 color photographs, the book is even more thorough in its coverage of the medical, pharmacological, and surgical treatment of uveitis. You will also find the most up-to-date information on other conditions associated with uveitis, including inflammatory complications of AIDS. A Brandon Hill Title




Ocular Manifestations of Systemic Disease


Book Description

This set addresses the numerous ocular conditions that accompany a broad range of systemic disorders. Particular attention is given to AIDS.