OECD Guidelines for Testing of Chemicals


Book Description




OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 452: Chronic Toxicity Studies


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The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...







Animal Hematotoxicology


Book Description

Hematology data from in vivo toxicology studies remains one of the most predictive measures for human risk, as the same measurements made in pre-clinical toxicology studies can be made in early clinical trials. Covering the three main blood cell types - erythrocytes, leukocytes and thrombocytes, this work is designed to clarify topics fo




OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Report of the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Environmental Persistence and Long Range Transport in the Context of PBTS/POPS Assessment


Book Description

This document contains the report from the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Persistence and Long-range Transport in the Context of PBTs/POPs Assessment, held on 29-31 October 2001 in Ottawa, Canada, together ...




Mixture Toxicity


Book Description

In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an




OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Guidance Notes for Analysis and Evaluation of Chronic Toxicity and Carcinogenicity Studies


Book Description

These Guidance Notes outline core concepts in order to obviate the need to consult large numbers of text books, while still pointing the reader to sources of more detailed or specific information.




OECD Guidelines for the Testing of Chemicals / OECD Series on Testing and Assessment Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures


Book Description

This document sets out the objectives, organisational context, and plan for a Harmonised Integrated Classification System for Human Health and Environmental Hazards of Chemical Substances and Mixtures.







Hayes' Handbook of Pesticide Toxicology


Book Description

The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book's tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. - Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. - Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions - All major classes of pesticide considered - Different routes of exposure critically evaluated