Author : OECD
Publisher : OECD Publishing
Page : 4 pages
File Size : 17,35 MB
Release : 1986-10-23
Category :
ISBN : 9264071482
The mouse spot test detects presumed somatic mutations in fetal cells following transplacental absorption of the test substance. This is an in vivo test in mice in which developing embryos are exposed to a chemical (solid, liquid, vapour or ...
Author : OECD
Publisher : OECD Publishing
Page : 12 pages
File Size : 27,71 MB
Release : 2006-09-11
Category :
ISBN : 9264035443
Author : OECD
Publisher : OECD Publishing
Page : 27 pages
File Size : 37,36 MB
Release : 2009-09-08
Category :
ISBN : 9264076034
The method described by this Test Guideline provides information that allows hazard assessment for short-term exposure to a test article by inhalation, and allows the substance to be classified according to the Globally Harmonized System of ...
Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 42,90 MB
Release : 2009-09-08
Category :
ISBN : 9264070605
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 39,70 MB
Release : 2018-06-27
Category :
ISBN : 9264284168
This method provides information on health hazard likely to arise from short-term exposure to a test chemical by inhalation. It is a principle of the method that only moderately toxic concentrations are used so that ‘evident toxicity’, rather than death/moribundity is used as an endpoint, and ...
Author : OECD
Publisher : OECD Publishing
Page : 14 pages
File Size : 40,66 MB
Release : 2002-02-08
Category :
ISBN : 926407094X
A principle of the method is that in the main study only moderately toxic doses are used, and the administration of doses that are expected to be lethal should be avoided. This Guideline is intended primarily for use with rat. Groups of animals of a ...
Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 17,51 MB
Release : 2018-06-27
Category :
ISBN : 9264071229
The objective of a combined chronic toxicity/carcinogenicity study is to identify carcinogenic and the majority of chronic effects, and to determine dose-response relationships following prolonged and repeated exposure. The rat is typically used for ...
Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : pages
File Size : 12,24 MB
Release : 1981
Category : Chemical industry
ISBN : 9789264122215
Author : OECD
Publisher : OECD Publishing
Page : 29 pages
File Size : 42,76 MB
Release : 2008-10-16
Category :
ISBN : 9264071040
The method permits estimation of an LD50 with a confidence interval and the results allow a substance to be classified for acute toxicity according to the Globally Harmonised System of classification and labelling of chemicals. It is easiest to ...
Author : OECD
Publisher : OECD Publishing
Page : 98 pages
File Size : 47,35 MB
Release : 2001-03-28
Category :
ISBN : 9264192646
The OECD Guidelines for the Testing of Chemicals are a collection of the most relevant internationally agreed testing methods used by government, industry and independent laboratories when testing the safety of new and existing chemicals as well as ...
