Author : OECD
Publisher : OECD Publishing
Page : 26 pages
File Size : 11,40 MB
Release : 2007-10-15
Category :
ISBN : 9264067396
A developmental neurotoxicity study will provide information on the effects of repeated exposure to a substance during in utero and early postnatal development. The test substance is administered daily, generally orally, to mated females (rats are ...
Author : OECD
Publisher : OECD Publishing
Page : 15 pages
File Size : 19,89 MB
Release : 1997-07-21
Category :
ISBN : 9264071024
This Test Guideline has been designed to obtain the information necessary to confirm or to further characterise the potential neurotoxicity of chemicals in adult animals. This Test Guideline is designed for use with the rat. It specifically ...
Author : OECD
Publisher : OECD Publishing
Page : 14 pages
File Size : 17,73 MB
Release : 2018-06-27
Category :
ISBN : 9264070826
This Test Guideline for developmental toxicity testing is designed to provide general information concerning the effects of prenatal exposure on the pregnant test animal and on the developing organism. The test substance is normally administered to ...
Author : OECD
Publisher : OECD Publishing
Page : 8 pages
File Size : 12,47 MB
Release : 1995-07-27
Category :
ISBN : 9264070907
The test substance is administered orally in a single dose to domestic hens. The animals are observed for 21 days, then the remainder of the hens are killed and histopathological examination is undertaken. The young adult domestic laying hen (Gallus ...
Author : OECD
Publisher : OECD Publishing
Page : 7 pages
File Size : 27,55 MB
Release : 1995-07-27
Category :
ISBN : 9264070923
This Test Guideline is used in the assessment and evaluation of the toxic effects of organophosporus substances. Daily doses of the test substance are administered orally (preferably by gavage or administration of gelatin capsules) to domestic ...
Author : OECD
Publisher : OECD Publishing
Page : 20 pages
File Size : 23,74 MB
Release : 2009-09-08
Category :
ISBN : 9264070605
This method provides information on health hazard likely to arise from short-term exposure to a test article (gas, vapour or aerosol/particulate test article) by inhalation. The revised Test Guideline describes two studies: a traditional LC50 ...
Author : OECD
Publisher : OECD Publishing
Page : 10 pages
File Size : 17,57 MB
Release : 1995-07-27
Category :
ISBN : 9264070966
The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should be dosed throughout the study, so approximately 54 days. This Test Guideline is designed ...
Author : OECD
Publisher : OECD Publishing
Page : 19 pages
File Size : 26,65 MB
Release : 2016-07-29
Category :
ISBN : 926426440X
This screening Test Guideline describes the effects of a test chemical on male and female reproductive performance. It has been updated with endocrine disruptor endpoints, in particular measure of anogenital distance and male nipple retention in pups and thyroid examination.
Author : OECD
Publisher : OECD Publishing
Page : 14 pages
File Size : 49,38 MB
Release : 2002-02-08
Category :
ISBN : 9264071008
This is a test guideline for testing for Acute Oral Tosxidity using the Acute Toxic Class Method.
Author : OECD
Publisher : OECD Publishing
Page : 18 pages
File Size : 48,75 MB
Release : 2018-06-27
Category :
ISBN : 9264071202
The objective of these chronic toxicity studies is to characterize the profile of a substance in a mammalian species (primarily rodents) following prolonged and repeated exposure. The Test Guideline focuses on rodents and oral administration. Both ...
