Book Description
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology for human recombinant in vitro assays to detect substances with estrogen receptor binding affinity (hrER binding assays).
Author : OECD
Publisher : OECD Publishing
Page : 60 pages
File Size : 45,89 MB
Release : 2024-06-25
Category :
ISBN : 9264242627
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology for human recombinant in vitro assays to detect substances with estrogen receptor binding affinity (hrER binding assays).
Author : OECD
Publisher : OECD Publishing
Page : 74 pages
File Size : 39,18 MB
Release : 2021-06-17
Category :
ISBN : 9264265295
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology of Stably Transfected Transactivation to detect Estrogen Receptor Agonists and Antagonists (ER TA assays).
Author :
Publisher :
Page : 64 pages
File Size : 15,83 MB
Release : 2015
Category :
ISBN :
Author : OECD
Publisher : OECD Publishing
Page : 26 pages
File Size : 49,22 MB
Release : 2012-10-02
Category :
ISBN : 9264185399
This Test Guideline describes an in vitro assay, which provides concentration-response data for substances with in vitro ER agonist and antagonist activity. The test system utilises the BG1Luc4E2 cell line derived from a human ovarian adenocarcinoma ...
Author : Julian Blasco
Publisher : CRC Press
Page : 306 pages
File Size : 50,12 MB
Release : 2019-07-19
Category : Science
ISBN : 1351657542
The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.
Author : Ramesh C Gupta
Publisher : Academic Press
Page : 1558 pages
File Size : 18,14 MB
Release : 2022-02-11
Category : Medical
ISBN : 0323915604
Reproductive and Developmental Toxicology, Third Edition is a comprehensive and authoritative resource, providing the latest literature on this complex subject by focusing on three core components - parent, placenta and fetus - and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics including nanoparticles and radiation, gases and solvents, smoking, alcohol and drugs of abuse, and metals, among others. In addition, it is the only resource to include reproductive and developmental toxicity in domestic animals, fish and wildlife With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages. Completely revised and updated to include the most recent developments in the field, this book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists and teratologists from academia, industry and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and development Offers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis Includes new chapters on developments in systems toxicology and predictive modeling of male developmental toxicity, adverse outcome pathways in reproductive and developmental toxicology, ovarian and endometrial toxicity, developmental neurotoxicity of air pollution, and more
Author : OECD
Publisher : OECD Publishing
Page : 53 pages
File Size : 19,12 MB
Release : 2015-07-28
Category :
ISBN : 9264243046
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provide the methodology of Stably Transfected Transactivation to detect Estrogen Receptor Agonists and Antagonists (ER TA assays).
Author : OECD
Publisher : OECD Publishing
Page : 39 pages
File Size : 29,78 MB
Release : 2012-10-02
Category :
ISBN : 9264185380
This Performance-Based Test Guideline (PBTG) describes in vitro assays, which provides the methodology of Stably Transfected Transactivation to detect Estrogen Receptor Agonists (ER TAs). It comprises mechanistically and functionally similar test ...
Author :
Publisher : Elsevier
Page : 8639 pages
File Size : 18,63 MB
Release : 2017-12-01
Category : Science
ISBN : 0081006128
Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts
Author : Organisation for Economic Co-operation and Development
Publisher : Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
Page : pages
File Size : 19,85 MB
Release : 1981
Category : Chemical industry
ISBN : 9789264122215