OECD Series on Testing and Assessment Guidance Document on the Honey Bee (Apis Mellifera L.) Brood test Under Semi-field Conditions


Book Description

The method described in this guidance document assesses the effects of plant protection products (PPPs), and has been validated using the active Fenoxycarb, which is known to act as an insect growth regulator (IGR), to the honey bee brood (Apis mellifera L.).







OECD Series on Testing and Assessment Guidance on Grouping of Chemicals


Book Description

This guidance document provides guidance for assessing the hazards of chemical substances while gaining efficiencies and improving animal welfare. The approach described in this guidance document is to consider closely related chemicals as a group, or category, rather than as individual chemicals.




OECD Series on Testing and Assessment The Guidance Document for Using the OECD (Q)SAR Application Toolbox to Develop Chemical Categories According to the OECD Guidance on Grouping Chemicals


Book Description

This document provides guidance on how to use the OECD (Q)SAR Application Toolbox to build chemical categories according to the OECD Guidance on Grouping of Chemicals. It is part of an overall effort to provide guidance on the use of the (Q)SAR Application Toolbox.




OECD Series on Testing and Assessment The Adverse Outcome Pathway for Skin Sensitisation Initiated by Covalent Binding to Proteins


Book Description

This document describes the state of knowledge of the adverse outcome pathway (AOP) for skin sensitisation initiated by covalent binding to proteins, assesses the weight-of-evidence supporting the AOP, identifies the key events, and identifies databases containing test results related to key events.




OECD Series on Testing and Assessment Detailed Review Paper (DRP) on Molluscs Life-cycle Toxicity Testing


Book Description

This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.




OECD Series on Testing and Assessment Detailed Review Paper on the Use of Metabolising Systems for In Vitro Testing of Endocrine Disruptors


Book Description

This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.







OECD Series on Testing and Assessment Fish Toxicity Testing Framework


Book Description

This document presents a review of fish toxicity testing for the regulatory purpose of chemical safety. The main focus is on fish toxicity, but fish bioaccumulation is also considered where relevant.