Optimizing Breast Cancer Management


Book Description

This book presents expert opinions on a variety of key topics related to the management of breast cancer, with a focus on the implications of recent advances and research findings for clinical practice. It also explores the controversy regarding mammography screening and reviews the contribution of new imaging modalities. Considerable attention is paid to developments in surgical procedures, including the potential for the safe and effective use of sentinel lymph node dissection alone—even in patients with positive nodes—and to the advantages and contraindications of new radiotherapy techniques. Genetic aspects are discussed in detail, including an assessment of the role of genetic testing and the potential impact of genetic signatures on breast cancer management. New systemic strategies, such as anti-HER2 therapy, endocrine agents, and agents to reverse endocrine resistance, are considered, and the optimal use of chemotherapy for early-stage and advanced-stage disease is addressed. In closing, the book shares important new insights into lifestyle risk factors, risk reduction strategies, and survivor issues, including sexual dysfunction and fertility maintenance.




Breast Cancer: Global Quality Care


Book Description

Developing or existing breast cancer centres strive to provide the highest quality care possible within their current financial and personnel resources. Although the basics in diagnosis and treatment of breast cancer are well known, providing, monitoring, and assessing the care offered can be challenging for most sites. Based on the work of the International Congress of Breast Disease Centres, this book provides a comprehensive overview of how to start or improve a breast unit wherever you live. Written by a multidisciplinary team of over 100 experts from 25 countries, it provides a practical guide for how to optimally organise high quality integrated breast cancer care, whilst taking into account the local economics and resources available to different countries. Each component of the care pathway, including imaging, surgery, systemic treatment, nursing, and genetic assessment, is discussed from a theoretical and practical aspect. The authors define targets to strive for, methods to assess care, and key recommendations for how to improve within existing limitations. Finally, the book looks beyond the breast care unit to consider accreditation and certification, emerging technologies, media, and the role of governments. This guide will be valuable for anyone working in the field of integrated breast cancer care, including established breast care experts, those new to the field, and policy makers interested in the social, financial, and political aspects of improving breast care quality.










Advances in Breast Cancer Management, 2nd edition


Book Description

The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh discusses the consequences of estrogen deprivation and the ways of ameliorating secondary symptoms and the potential long-term morbidity. Drs. Haigh and Guiliano review the sentinel lymph node biopsy technique including results from their extensive experience. Dr. Abram Recht places into perspective the potential benefit of post-mastectomy radiotherapy and reviews recent trials that address this issue. Dr. Dennis Slamon takes from us from the laboratory to the clinic in explaining the development of Herceptin as a paradigm for therapy targeted to specific molecular characteristics of breast cancer tumor cells. Drs. Nieto, Shpall, Crump and Pritchard offer different perspectives on the future of high-dose chemotherapy with stem cell transplantation as a treatment for breast cancer patients. Drs.




Toxicities of Radiation Treatment for Breast Cancer


Book Description

This book is a comprehensive guide to breast toxicity. Adjuvant radiation remains standard for a majority of women who undergo breast-conserving surgery for breast cancer, and indications for post-mastectomy and regional lymph node irradiation have also broadened with recent publications. At the same time, locoregional recurrence has declined and survival has improved in recent decades. In the current era of excellent breast cancer outcomes, then, considering the balance between toxicity and outcomes becomes paramount. Several recent editorials recommend considering toxicity against the potential benefit of adjuvant radiation in tailoring radiation decisions for individual patients. Thus, a clear understanding of the potential toxicities of adjuvant radiation for breast cancer is critical to optimizing outcomes in modern breast cancer management. Here, authors have collected recent data focused on toxicity of treatment that provide an opportunity for improving this optimization. Chapters cover both acute and late toxicity of radiation for breast cancer, including tailored risk assessment for each of these potential toxicities, considerations for including risk of toxicity in management decisions, and toxicity management strategies. This is an ideal guide for radiation oncologists, residents, and oncologists seeking to optimize care for their patients.










Approaches and Applications of Deep Learning in Virtual Medical Care


Book Description

The recent advancements in the machine learning paradigm have various applications, specifically in the field of medical data analysis. Research has proven the high accuracy of deep learning algorithms, and they have become a standard choice for analyzing medical data, especially medical images, video, and electronic health records. Deep learning methods applied to electronic health records are contributing to understanding the evolution of chronic diseases and predicting the risk of developing those diseases. Approaches and Applications of Deep Learning in Virtual Medical Care considers the applications of deep learning in virtual medical care and delves into complex deep learning algorithms, calibrates models, and improves the predictions of the trained model on medical imaging. Covering topics such as big data and medical sensors, this critical reference source is ideal for researchers, academicians, practitioners, industry professionals, hospital workers, scholars, instructors, and students.




Breasts: The Owner's Manual


Book Description

A national bestseller! Breast cancer surgeon Dr. Kristi Funk offers a comprehensive and encouraging approach to breast care and breast cancer. Empower yourself with facts and strategies to understand your breasts, reduce your cancer risk, and open your eyes to interventions and treatments. Most women don’t want to hear about breast cancer unless they have it and need to make some decisions, but these days news about breast cancer—the number one killer of women ages twenty to fifty-nine—is everywhere. Chances are you know someone who has had it. But did you know that choices you make every day bring you closer to breast cancer—or move you farther away? That there are ways to reduce your risk factors? And that many of the things you’ve heard regarding the causes of breast cancer are flat-out false? Based on Dr. Kristi Funk’s experience as a board-certified breast cancer surgeon, she knows for a fact that women have the power to reduce breast cancer risk in dramatic ways. Many women believe that family history and genetics determine who gets breast cancer, but that’s not true for most people. In fact, 87 percent of women diagnosed with breast cancer do not have a single first-degree relative with breast cancer. This book will help you: Learn the breast-health basics that every woman should know Reduce your cancer risk and recurrence risk based on food choices and healthy lifestyle changes backed by rigorous scientific research Understand the controllable and uncontrollable risk factors for breast cancer Outline your medical choices if you're at elevated risk for or are already navigating life with breast cancer There have been few solid guidelines on how to improve your breast health, lower your risk of getting cancer, and make informed medical choices after treatment—until now. With her book available in 10 languages and in more than 30 countries, Dr. Funk is passionate about her mission of educating as many women as possible about what they can do to stop breast cancer before it starts. Praise for Breasts: The Owner’s Manual: “Dr. Funk writes Breasts: The Owner’s Manual just like she talks: with conviction, passion, and a laser focus on you.”—Dr. Mehmet Oz, Host of The Dr. Oz Show “Breasts: The Owner’s Manual will become an indispensable and valued guide for women looking to optimize health and minimize breast illness.”—Debu Tripathy, MD, Professor and Chair, Department of Breast Medical Oncology, University of Texas MD Anderson Cancer Center “Breasts: The Owner’s Manual not only provides a clear path to breast health, but a road that leads straight to your healthiest self. As someone who has faced breast cancer, I suggest you follow it.”—Robin Roberts, Co-anchor, Good Morning America