Organic Synthesis, Natural Products Isolation, Drug Design, Industry and the Environment


Book Description

Over the years, applications of various non-conventional solvents diversified in various fields such as organic synthesis, natural products, drug design, pharmaceuticals, dyes and agrochemical industries. This book consists of nine chapters, which present recent advances and applications of various non-conventional solvents in organic transformations, drug design and bioremediation. Environmental impacts of non-conventional solvents and comparison between traditional solvents and non-conventional solvents are also discussed in this book.




Organic Synthesis, Natural Products Isolation, Drug Design, Industry and the Environment


Book Description

Over the years, applications of various non-conventional solvents diversified in various fields such as organic synthesis, natural products, drug design, pharmaceuticals, dyes and agrochemical industries. This book consists of nine chapters, which present recent advances and applications of various non-conventional solvents in organic transformations, drug design and bioremediation. Environmental impacts of non-conventional solvents and comparison between traditional solvents and non-conventional solvents are also discussed in this book.




Ionic Liquids, Deep Eutectic Solvents, Crown Ethers, Fluorinated Solvents, Glycols and Glycerol


Book Description

Over the years, the uses and applications of various non-conventional solvents such as ionic liquids, deep eutectic solvents, crown ethers, fluorinated solvents, glycols, glycerol etc diversified in various fields. This book consists of nine chapters, which present recent advances and outlook on various non-conventional solvents in organic transformations. Comparison between traditional solvents and non-conventional solvents are also highlighted in this book.




Supramolecular Chemistry


Book Description

This introductory textbook on supramolecular chemistry is a thoroughly revised and expanded version of the 1st edition, originally published in 2020. All chapters have been brought up to date and now include "Further Reading" sections that highlight relevant developments. In addition, a new chapter on supramolecular polymers has been added. With these changes, this book provides an even more comprehensive introduction to the exciting field of supramolecular chemistry than before. Readers will learn what forces hold supramolecular architectures together, how supramolecular systems are created and characterized, how molecular switches, motors, transporters, catalysts, chemosensors, and other functional systems work, and where supramolecular chemistry can play or already plays a role in our lives. In 2022 the first edition of this book won the Literature Prize of the German Chemical Industry Association VCI. For the full press release (in German): https://www.vci.de/fonds/presse-und-infos/pressemitteilungen/preisgeld-fuer-supramolekuele.jsp




Drug Discovery from Natural Products


Book Description

An integrated review of the most recent trends in natural products, drug discovery, and key lead candidates that are outstanding for their chemistry and biology in novel drug development.




Natural Product Extraction


Book Description

Natural products are sought after by the food, pharmaceutical and cosmetics industries, and research continues into their potential for new applications. Extraction of natural products in an economic and environmentally-friendly way is of high importance to all industries involved. This book presents a holistic and in-depth view of the techniques available for extracting natural products, with modern and more environmentally-benign methods, such as ultrasound and supercritical fluids discussed alongside conventional methods. Examples and case studies are presented, along with the decision-making process needed to determine the most appropriate method. Where appropriate, scale-up and process integration is discussed. Relevant to researchers in academia and industry, and students aiming for either career path, Natural Product Extraction presents a handy digest of the current trends and latest developments in the field with concepts of Green Chemistry in mind.




Total Synthesis of Natural Products


Book Description

'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.




Natural Products Isolation


Book Description

The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.




Green Approaches in Medicinal Chemistry for Sustainable Drug Design


Book Description

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis




The Role of Natural Products in Drug Discovery


Book Description

Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.