Laboratory Animal Anaesthesia


Book Description

Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals' body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals.• New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field




Anesthesia and Analgesia in Laboratory Animals


Book Description

Anesthesia and Analgesia in Laboratory Animals focuses entirely on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Sponsored by the American College of Laboratory Animal Medicine, this informative work provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Focuses on a wide variety of animal species used in research - Provides a comprehensive overview of the pharmacology of anesthetics and analgesics - Includes monitoring of analgesia and anesthesia - Organizes topics by species for agents and methods of providing anesthesia, analgesia, and post-op care to animals - No other American text is devoted entirely to this topic




Definition of Pain and Distress and Reporting Requirements for Laboratory Animals


Book Description

In this first in a proposed series of workshops on regulatory issues in animal care and use, the Institute for Laboratory Animal Research (ILAR) has addressed the existing and proposed requirements for reporting pain and distress in laboratory animals. The Animal Welfare Act, administered by the Animal and Plant Health Inspection Service of the United States Department of Agriculture (USDA), mandates that pain and distress in laboratory animals be minimized. USDA is considering two policy changes with regard to this specific mandate. Firstly, since there has been no functional definition of "distress," USDA has prepared such a definition and requested feedback from the scientific community on its usefulness for regulatory and reporting requirements. The second issue concerns the pain and distress categorization scheme for reporting to USDA. Various groups and individuals have questioned the efficacy of the current categories, and specific changes have been proposed by the Humane Society of the United States. USDA is considering these and other potential changes to the existing scheme. Thus, given these potential changes to animal welfare policy, the aim of the ILAR/NIH joint workshop was to provide feedback to the USDA. The speakers were asked to address these two issues as well as to comment upon whether the information contained in the 1992 ILAR report Recognition and Alleviation of Pain and Distress in Laboratory Animals is still useful to investigators in assisting them to comply with regulations. The speakers provided perspectives based on their individual expertise in the areas of science of pain and distress, animal welfare policy, protocol review, and/or as representatives of relevant organizations or institutions. The following proceedings are an edited transcript of their presentations.




Anesthesia and Analgesia in Laboratory Animals


Book Description

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery. Fully revised and updated this new edition provides the reader with agents, methods, and techniques for anesthesia and analgesia that ensure humane and successful procedural outcomes. - Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals - Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish, and invertebrates - Includes hot topic areas such as pain research, ethical issues, legal issues, and imaging studies




Recognition and Alleviation of Pain and Distress in Laboratory Animals


Book Description

Clear guidelines on the proper care and use of laboratory animals are being sought by researchers and members of the many committees formed to oversee animal care at universities as well as the general public. This book provides a comprehensive overview of what we know about behavior, pain, and distress in laboratory animals. The volume explores: Stressors in the laboratory and the animal behaviors they cause, including in-depth discussions of the physiology of pain and distress and the animal's ecological relationship to the laboratory as an environment. A review of euthanasia of lab animals-exploring the decision, the methods, and the emotional effects on technicians. Also included is a highly practical, extensive listing, by species, of dosages and side effects of anesthetics, analgesics, and tranquilizers.




Veterinary Anesthesia and Analgesia


Book Description

Veterinary Anesthesia and Analgesia: the Fifth Edition of Lumb and Jones is a reorganized and updated edition of the gold-standard reference for anesthesia and pain management in veterinary patients. Provides a thoroughly updated edition of this comprehensive reference on veterinary anesthesia and analgesia, combining state-of-the-art scientific knowledge and clinically relevant information Covers immobilization, sedation, anesthesia, and analgesia of companion, wild, zoo, and laboratory animals Takes a body systems approach for easier reference to information about anesthetizing patients with existing conditions Adds 10 completely new chapters with in-depth discussions of perioperative heat balance, coagulation disorders, pacemaker implantation, cardiac output measurement, cardiopulmonary bypass, shelter anesthesia and pain management, anesthetic risk assessment, principles of anesthetic pharmacology, and more Now printed in color, with more than 400 images




Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research


Book Description

Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.




Recognition and Alleviation of Pain in Laboratory Animals


Book Description

The use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare.




Pain Management in Animals


Book Description

An ever-increasing number of drugs are available to veterinarians for use in the control of pain. This new, concise guide gives vets with all the information they need to choose the most appropriate pain medication for any clinical situation. Introductory chapters explain the physiology of pain and the pharmacology of analgesics, and are followed by detailed chapters on management of acute and post-operative pain and chronic pain, the problems of pain management and pain assessment. Written by an international team of veterinary pain management experts, Pain Management in Animals provides vets with all the information they need to provide good pain control in all their patients.




Essentials of Small Animal Anesthesia and Analgesia


Book Description

Essentials of Small Animal Anesthesia and Analgesia, Second Edition presents the fundamentals of managing small animal anesthesia patients in a clinically relevant, accessible manual. The bulk of the book is distilled from Lumb and Jones' Veterinary Anesthesia and Analgesia to provide authoritative information in a quick-reference format, with references to Lumb and Jones' throughout for easy access to further detail. Logically reorganized with an easy-to-use structure and an increased focus on pain management, this new edition features new chapters on equipment and managing specific conditions. The Second Edition has been updated to reflect current practices in anesthesia and analgesia, and a new companion website offers review questions and answers, video clips, and an image bank with additional figures not found in the printed book. Essentials of Small Animal Anesthesia and Analgesia, Second Edition provides veterinary care providers and students with key information on anesthetic and analgesic pharmacology, physiology, patient assessment, and clinical case management.