Pancreatic Cancer, An Issue of Hematology/Oncology Clinics of North America


Book Description

This issue of Hematology/Oncology Clinics of North America is devoted to Pancreatic Cancer. Guest Editor Brian Wolpin, MD has assembled a group of expert authors to review the following topics: Biology and genetics of pancreatic adenocarcinoma; Mouse models of pancreatic adenocarcinoma; Epidemiology and inherited predisposition for sporadic pancreatic adenocarcinoma; Familial pancreatic adenocarcinoma; Imaging and endoscopic approaches to pancreatic cancer; Diagnosis and management of pancreatic cystic neoplasms; Surgical management of pancreatic cancer; Peri-operative therapy for surgically resectable pancreatic adenocarcinoma; Diagnosis and management of borderline resectable pancreatic adenocarcinoma; Treatment approaches to locally advanced pancreatic adenocarcinoma; Therapeutic approaches for metastatic pancreatic adenocarcinoma; Supportive and end-of-life care for patients with pancreatic adenocarcinoma; and Novel therapeutics for pancreatic adenocarcinoma.




Pancreatic Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book


Book Description

In this issue of Hematology/Oncology Clinics, guest editors Drs. Matthew B. Yurgelun and Douglas A. Rubinson bring their considerable expertise to the topic of Pancreatic Cancer. Top experts in the field cover key topics such as pancreatic adenocarcinoma: trends in epidemiology, risk factors, and outcomes; decision making regarding perioperative therapy in individuals with localized pancreatic adenocarcinoma; the evolving role of radiotherapy in the management of individuals with pancreatic adenocarcinoma; and more. - Contains 14 relevant, practice-oriented topics including diabetes, cachexia, sarcopenia, and metabolic factors in individuals with pancreatic adenocarcinoma; PARP inhibitors and other novel therapeutics in pancreatic adenocarcinoma; screening and surveillance for pancreatic adenocarcinoma in high-risk individuals; germline testing for individuals with pancreatic adenocarcinoma and novel genetic risk factors; and more. - Provides in-depth clinical reviews on pancreatic cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Bladder Cancer, An Issue of Hematology/Oncology Clinics of North America


Book Description

This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Joaquin Bellmunt, is devoted to Bladder Cancer. Articles in this issue include: Diagnosis and Staging of Bladder Cancer; Epidemiology of Bladder Cancer; Molecular Biology of Bladder Cancer; Pharmacogenomics in Bladder Cancer; Management of Non-muscle Invasive Bladder Cancer; Non-urothelial Bladder Cancer and Rare Variant Histologies; Management of UUT; New Trends in Surgical Management of Bladder Cancer; Bladder Preservation Strategies; Perioperative Therapy of Bladder Cancer (Neoadjuvant and Adjuvant); First Line Treatment and Prognostic Factors of Metastatic Disease: Platinum Eligible Patients; First Line Treatment of Metastatic Disease: Platinum Ineligible Patients; Salvage Therapy in Metastatic Disease; and Future Directions and Targeted Therapies in Bladder Cancer.




Neuroendocrine Tumors, An Issue of Hematology/Oncology Clinics of North America


Book Description

This issue of Hematology/Oncology Clinics of North America is devoted to Neuroendocrine tumors. Articles in this issue include: Pathology Classification of Neuroendocrine Tumors; Clinical Presentation and Diagnosis of Neuroendocrine Tumors; Surgical Management of Gastrointestinal Carcinoid Tumors; Systemic Therapies for Advanced Gastrointestinal Carcinoid Tumors; Thymic and Bronchial Carcinoid Tumors; Surgical Management of Pancreatic Neuroendocrine Tumors; Systemic Therapies for Advanced Pancreatic Neuroendocrine Tumors; Pheochromocytoma and Paraganglioma; Poorly Differentiated Neuroendocrine Tumors; Role of Somatostatin Analogs in the Treatment of Neuroendocrine Tumors; Peptide Receptor Radiotherapy in the Treatment of Neuiroendocrine Tumors; Hepatic-Directed Therapies in Patients with Neuroendocrine Tumors; and Neuroendocrine Tumor Clinical Trial Interpretation and Design.




Colorectal Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book


Book Description

In this issue of Hematology/Oncology Clinics, guest editors Drs. Kimmie Ng and Benjamin L. Schlechter bring their considerable expertise to the topic of Colorectal Cancer. Despite tremendous progress in the management of this disease, many questions and controversies remain regarding screening, adjuvant therapy for resected colon cancers, targeted therapies and immunotherapy for patients with advanced disease, surgical management, and more. In this issue, top experts in the field address provide clinicians with the tools to individualize management and optimize care for this growing patient population. - Contains 13 relevant, practice-oriented topics including screening for colorectal cancer; hereditary colorectal cancer; disparities in colorectal cancer; microbiome in colorectal cancer; impact of diet and exercise on colorectal cancer; colorectal cancer in younger adults; and more. - Provides in-depth clinical reviews on colorectal cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Pancreatic Cancer, An Issue of Hematology/Oncology Clinics of North America


Book Description

In this issue of Hematology/Oncology Clinics, guest editors Drs. Matthew B. Yurgelun and Douglas A. Rubinson bring their considerable expertise to the topic of Pancreatic Cancer. Top experts in the field cover key topics such as pancreatic adenocarcinoma: trends in epidemiology, risk factors, and outcomes; decision making regarding perioperative therapy in individuals with localized pancreatic adenocarcinoma; the evolving role of radiotherapy in the management of individuals with pancreatic adenocarcinoma; and more. Contains 14 relevant, practice-oriented topics including diabetes, cachexia, sarcopenia, and metabolic factors in individuals with pancreatic adenocarcinoma; PARP inhibitors and other novel therapeutics in pancreatic adenocarcinoma; screening and surveillance for pancreatic adenocarcinoma in high-risk individuals; germline testing for individuals with pancreatic adenocarcinoma and novel genetic risk factors; and more. Provides in-depth clinical reviews on pancreatic cancer, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Cancer Precursor Conditions and their Detection, An Issue of Hematology/Oncology Clinics of North America


Book Description

In this issue of Hematology/Oncology Clinics, guest editor Dr. Elizabeth K. O'Donnell brings her considerable expertise to the topic of Cancer Precursor Syndromes and Their Detection. Top experts focus on cancer precursors for different sites, with articles on the risk-benefit analysis of early interception; plasma cell precursors; early detection and interception of lung cancer, cervical cancer, GI cancers, skin cancer; and head and neck cancer; biomarkers and early detection; and more. - Contains 12 relevant, practice-oriented topics including clonal hematopoiesis of indeterminate potential (CHIP); prostate cancer: early detection and intervention; ductal carcinoma in situ; cancer prevention; and more. - Provides in-depth clinical reviews on cancer precursor syndromes and their detection, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Complement-mediated Hemolytic Anemias, An Issue of Hematology/Oncology Clinics of North America


Book Description

This issue of Hematology/Oncology Clinics of North America, guest edited by Dr. Robert Brodsky, is devoted to Complement-mediated Hemolytic Anemias. Articles in this outstanding issue include: Complement: An overview for the clinician; Warm autoimmune hemolytic anemia; Cold Agglutinin Disease; ABO incompatible blood transfusions; Paroxysmal cold hemoglobinuria; Paroxysmal nocturnal hemoglobinuria; Congenital CD59 deficiency; Atypical Hemolytic Uremic Syndrome (HUS); Typical Hemolytic Uremic Syndrome (HUS); Thrombotic thrombocytopenic purpura; and Pharmacologic complement inhibitors.




Breast Cancer, An Issue of Hematology/Oncology Clinics of North America, E-Book


Book Description

In this issue of Hematology/Oncology Clinics, guest editor Dr. Harold J. Burstein brings his considerable expertise to Breast Cancer. Top experts provide a comprehensive update on multidisciplinary management of early- and late-stage breast cancer, including key topics such as global perspectives on the epidemiology and treatment of breast cancer; breast cancer pathology in the era of genomics; optimizing radiation therapy after breast conserving surgery; and more. - Contains 16 relevant, practice-oriented topics including disparities in breast cancer outcomes and how to resolve them; genetic testing in breast cancer; the role of ovarian suppression in early stage premenopausal breast cancer; multidisciplinary management of brain metastases from breast cancer; evidence-based guidance for breast cancer survivorship; and more. - Provides in-depth clinical reviews on breast cancer, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Thalassemia, An Issue of Hematology/Oncology Clinics of North America, E-Book


Book Description

In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes. - Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. - Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.