The Absolutely True Diary of a Part-Time Indian (National Book Award Winner)


Book Description

A New York Times bestseller—over one million copies sold! A National Book Award winner A Boston Globe-Horn Book Award winner Bestselling author Sherman Alexie tells the story of Junior, a budding cartoonist growing up on the Spokane Indian Reservation. Determined to take his future into his own hands, Junior leaves his troubled school on the rez to attend an all-white farm town high school where the only other Indian is the school mascot. Heartbreaking, funny, and beautifully written, The Absolutely True Diary of a Part-Time Indian, which is based on the author's own experiences, coupled with poignant drawings by Ellen Forney that reflect the character's art, chronicles the contemporary adolescence of one Native American boy as he attempts to break away from the life he was destined to live. With a forward by Markus Zusak, interviews with Sherman Alexie and Ellen Forney, and black-and-white interior art throughout, this edition is perfect for fans and collectors alike.




MRCS Part B OSCEs


Book Description

Offers an introduction covering the MRCS exam with particular reference to OSCEs; an overview of clinical skills in history taking and physical examination; chapters covering sections of the exam with popular cases in the OSCE format at the end of each chapter; and, a layout with colour images.




MRCS Part A


Book Description

Helps candidates pass the new MRCS Part A exam. This book contains 4 complete practice papers, each featuring over 120 best of five questions, mirroring the format of the exam. It features questions which reflect the balance of topics covered in the actual exam. It includes explanations to every question to aid revision within the MRCS syllabus.




Protein Sensors of Reactive Oxygen Species, Part A: Selenoproteins and Thioredoxin


Book Description

This volume of Methods in Enzymology is concerned with the rapidly developing field of selenoprotein synthesis and its related molecular genetics. Progressive information on the topics of proteins as redox sensors, selenoproteins, and the thioredoxin system is studied using methods such as bioinformatics, DNA chip technology, cell biology, molecular genetics, and enzymology. The information on novel selenoproteins identified from genomic sequence data, as well as current knowledge on glutathione peroxidases, selenoprotein P, iodothyronine deiodinases, and thioredoxin reductases, is presented in a method-based approach.







Regulators of G Protein Signaling, Part A


Book Description

Regulators of G Protein Signaling, Part A is an in-depth treatment of G-Protein Signaling, and will cover general methods of analysis of RGS protein analysis, including Expression and post-translational modification, Assays of GAP activity and allosteric control, Electrophysiological methods and RGS-insensitive Ga subunits, Mouse models of RGS protein action, Methods of RGS protein inhibition, and G-protein regulators of model organisms. Table of Contents Expression and post-translational modification Assays of GAP activity and allosteric control Electrophysiological methods and RGS-insenstitive Ga subunits Mouse Models of RGS protein action Methods of RGS protein inhibition G-protein regulators of model organisms







Growth Factors, Part A


Book Description

This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease.




G Protein-Coupled Receptors - Part A


Book Description

G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes. Covers a broad range of topics related to GPCR activation and signaling Covers several receptor systems with an emphasis on emerging paradigms Covers different processes and model systems with a focus on GPCRs