Perspective of DNA Computing in Computer Science


Book Description

DNA or Deoxyribonucleic Acid computing is an emerging branch of computing that uses DNA sequence, biochemistry, and hardware for encoding genetic information in computers. Here, information is represented by using the four genetic alphabets or DNA bases, namely A (Adenine), G (Guanine), C (Cytosine), and T (Thymine), instead of the binary representation (1 and 0) used by traditional computers. This is achieved because short DNA molecules of any arbitrary sequence of A, G, C, and T can be synthesized to order. DNA computing is mainly popular for three reasons: (i) speed (ii) minimal storage requirements, and (iii) minimal power requirements. There are many applications of DNA computing in the field of computer science. Nowadays, DNA computing is widely used in cryptography for achieving a strong security technique, so that unauthorized users are unable to retrieve the original data content. In DNA-based encryption, data are encrypted by using DNA bases (A, T, G, and C) instead of 0 and 1. As four DNA bases are used in the encryption process, DNA computing supports more randomness and makes it more complex for attackers or malicious users to hack the data. DNA computing is also used for data storage because a large number of data items can be stored inside the condensed volume. One gram of DNA holds approx DNA bases or approx 700 TB. However, it takes approx 233 hard disks to store the same data on 3 TB hard disks, and the weight of all these hard disks can be approx 151 kilos. In a cloud environment, the Data Owner (DO) stores their confidential encrypted data outside of their own domain, which attracts many attackers and hackers. DNA computing can be one of the best solutions to protect the data of a cloud server. Here, the DO can use DNA bases to encrypt the data by generating a long DNA sequence. Another application of DNA computing is in Wireless Sensor Network (WSN). Many researchers are trying to improve the security of WSN by using DNA computing. Here, DNA cryptography is used along with Secure Socket Layer (SSL) that supports a secure medium to exchange information. However, recent research shows some limitations of DNA computing. One of the critical issues is that DNA cryptography does not have a strong mathematical background like other cryptographic systems. This edited book is being planned to bring forth all the information of DNA computing. Along with the research gaps in the currently available books/literature, this edited book presents many applications of DNA computing in the fields of computer science. Moreover, research challenges and future work directions in DNA computing are also provided in this edited book. - This edited book gives an overall detail of DNA computing and the fundamentals of cryptography - Many applications of DNA computing in computer science fields, such as cryptography, cloud computing, big data storage, Wireless Sensor Network (WSN) security, and many more, are presented in different chapters of this edited book - Research challenges along with many future work directions in DNA computing are presented in this edited book




DNA Computing


Book Description

This is the first book on DNA computing, a molecular approach that may revolutionize computing-replacing silicon with carbon and microchips with DNA molecules. The book starts with an introduction to DNA computing, exploring the power of complementarity, the basics of biochemistry, and language and computation theory. It then brings the reader to the most advanced theories develop thus far in this emerging research area.




Handbook of Natural Computing


Book Description

Natural Computing is the field of research that investigates both human-designed computing inspired by nature and computing taking place in nature, i.e., it investigates models and computational techniques inspired by nature and also it investigates phenomena taking place in nature in terms of information processing. Examples of the first strand of research covered by the handbook include neural computation inspired by the functioning of the brain; evolutionary computation inspired by Darwinian evolution of species; cellular automata inspired by intercellular communication; swarm intelligence inspired by the behavior of groups of organisms; artificial immune systems inspired by the natural immune system; artificial life systems inspired by the properties of natural life in general; membrane computing inspired by the compartmentalized ways in which cells process information; and amorphous computing inspired by morphogenesis. Other examples of natural-computing paradigms are molecular computing and quantum computing, where the goal is to replace traditional electronic hardware, e.g., by bioware in molecular computing. In molecular computing, data are encoded as biomolecules and then molecular biology tools are used to transform the data, thus performing computations. In quantum computing, one exploits quantum-mechanical phenomena to perform computations and secure communications more efficiently than classical physics and, hence, traditional hardware allows. The second strand of research covered by the handbook, computation taking place in nature, is represented by investigations into, among others, the computational nature of self-assembly, which lies at the core of nanoscience, the computational nature of developmental processes, the computational nature of biochemical reactions, the computational nature of bacterial communication, the computational nature of brain processes, and the systems biology approach to bionetworks where cellular processes are treated in terms of communication and interaction, and, hence, in terms of computation. We are now witnessing exciting interaction between computer science and the natural sciences. While the natural sciences are rapidly absorbing notions, techniques and methodologies intrinsic to information processing, computer science is adapting and extending its traditional notion of computation, and computational techniques, to account for computation taking place in nature around us. Natural Computing is an important catalyst for this two-way interaction, and this handbook is a major record of this important development.




DNA- and RNA-Based Computing Systems


Book Description

Discover the science of biocomputing with this comprehensive and forward-looking new resource DNA- and RNA-Based Computing Systems delivers an authoritative overview of DNA- and RNA-based biocomputing systems that touches on cutting-edge advancements in computer science, biotechnology, nanotechnology, and materials science. Accomplished researcher, academic, and author Evgeny Katz offers readers an examination of the intersection of computational, chemical, materials, and engineering aspects of biomolecular information processing. A perfect companion to the recently published Enzyme-Based Computing by the same editor, the book is an authoritative reference for those who hope to better understand DNA- and RNA-based logic gates, multi-component logic networks, combinatorial calculators, and related computational systems that have recently been developed for use in biocomputing devices. DNA- and RNA-Based Computing Systems summarizes the latest research efforts in this rapidly evolving field and points to possible future research foci. Along with an examination of potential applications in biosensing and bioactuation, particularly in the field of biomedicine, the book also includes topics like: A thorough introduction to the fields of DNA and RNA computing, including DNA/enzyme circuits A description of DNA logic gates, switches and circuits, and how to program them An introduction to photonic logic using DNA and RNA The development and applications of DNA computing for use in databases and robotics Perfect for biochemists, biotechnologists, materials scientists, and bioengineers, DNA- and RNA-Based Computing Systems also belongs on the bookshelves of computer technologists and electrical engineers who seek to improve their understanding of biomolecular information processing. Senior undergraduate students and graduate students in biochemistry, materials science, and computer science will also benefit from this book.




Computing with Cells and Atoms


Book Description

At the turning of the millennium, a switch in computing technology is forecasted and looked for. Two main directions of research, both based on quite unconventional ideas are most promising - quantum computing and molecular computing. In the last few years, both of these methods have been intensely investigated. The present book is the first "friendly" presentation of basic ideas in these exciting areas. The style is rigorous, but without entering into excessive technicalities. Equal attention is paid to the main practical results reported so far and the main theoretical developments. The book is written for the educated layman and is self-contained, including all the necessary facts from mathematics, computer science, biology and quantum mechanics.




Catalyzing Inquiry at the Interface of Computing and Biology


Book Description

Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.




Molecular Computational Models


Book Description

"Molecular Computation Models: Unconventional Approaches is looking into new computational paradigms from both a theoretical perspective which offers a solid foundation of the models developed, as well as from a modeling angle, in order to reveal their effectiveness in modeling and simulating, especially biological systems. Tools and programming concepts and implementation issues are also discussed in the context of some experiments and comparative studies"--Provided by publisher.




Handbook of Intelligent Computing and Optimization for Sustainable Development


Book Description

HANDBOOK OF INTELLIGENT COMPUTING AND OPTIMIZATION FOR SUSTAINABLE DEVELOPMENT This book provides a comprehensive overview of the latest breakthroughs and recent progress in sustainable intelligent computing technologies, applications, and optimization techniques across various industries. Optimization has received enormous attention along with the rapidly increasing use of communication technology and the development of user-friendly software and artificial intelligence. In almost all human activities, there is a desire to deliver the highest possible results with the least amount of effort. Moreover, optimization is a very well-known area with a vast number of applications, from route finding problems to medical treatment, construction, finance, accounting, engineering, and maintenance schedules in plants. As far as optimization of real-world problems is concerned, understanding the nature of the problem and grouping it in a proper class may help the designer employ proper techniques which can solve the problem efficiently. Many intelligent optimization techniques can find optimal solutions without the use of objective function and are less prone to local conditions. The 41 chapters comprising the Handbook of Intelligent Computing and Optimization for Sustainable Development by subject specialists, represent diverse disciplines such as mathematics and computer science, electrical and electronics engineering, neuroscience and cognitive sciences, medicine, and social sciences, and provide the reader with an integrated understanding of the importance that intelligent computing has in the sustainable development of current societies. It discusses the emerging research exploring the theoretical and practical aspects of successfully implementing new and innovative intelligent techniques in a variety of sectors, including IoT, manufacturing, optimization, and healthcare. Audience It is a pivotal reference source for IT specialists, industry professionals, managers, executives, researchers, scientists, and engineers seeking current research in emerging perspectives in the field of artificial intelligence in the areas of Internet of Things, renewable energy, optimization, and smart cities.




Structural DNA Nanotechnology


Book Description

Written by the founder of the field, this is a comprehensive and accessible introduction to structural DNA nanotechnology.




Computational Thinking: A Perspective on Computer Science


Book Description

This textbook is intended as a textbook for one-semester, introductory computer science courses aimed at undergraduate students from all disciplines. Self-contained and with no prerequisites, it focuses on elementary knowledge and thinking models. The content has been tested in university classrooms for over six years, and has been used in summer schools to train university and high-school teachers on teaching introductory computer science courses using computational thinking. This book introduces computer science from a computational thinking perspective. In computer science the way of thinking is characterized by three external and eight internal features, including automatic execution, bit-accuracy and abstraction. The book is divided into chapters on logic thinking, algorithmic thinking, systems thinking, and network thinking. It also covers societal impact and responsible computing material – from ICT industry to digital economy, from the wonder of exponentiation to wonder of cyberspace, and from code of conduct to best practices for independent work. The book’s structure encourages active, hands-on learning using the pedagogic tool Bloom's taxonomy to create computational solutions to over 200 problems of varying difficulty. Students solve problems using a combination of thought experiment, programming, and written methods. Only 300 lines of code in total are required to solve most programming problems in this book.