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Pharmaceutical Excipients

Author : Otilia M. Y. Koo

Publisher : John Wiley & Sons

Page : 369 pages

File Size : 19,6 MB

Release : 2016-10-03

Category : Medical

ISBN : 1118992423

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Book Description

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes the physico-chemical properties and biological effects of excipients Discusses chemical classes, safety and toxicity, and formulation Addresses recent efforts in the standardization and harmonization of excipients



Handbook of Pharmaceutical Excipients

Author : Raymond C. Rowe

Publisher : Amer Pharmacists Assn

Page : 888 pages

File Size : 19,30 MB

Release : 2009-01-01

Category : Medical

ISBN : 9781582121352

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Book Description

An internationally acclaimed reference work recognized as one of the most authoritative and comprehensive sources of information on excipients used in pharmaceutical formulation with this new edition providing 340 excipient monographs. Incorporates information on the uses, and chemical and physical properties of excipients systematically collated from a variety of international sources including: pharmacopeias, patents, primary and secondary literature, websites, and manufacturers' data; extensive data provided on the applications, licensing, and safety of excipients; comprehensively cross-referenced and indexed, with many additional excipients described as related substances and an international supplier's directory and detailed information on trade names and specific grades or types of excipients commercially available.



Pharmaceutical Excipients

Author : Otilia M. Y. Koo

Publisher : John Wiley & Sons

Page : 356 pages

File Size : 25,67 MB

Release : 2016-10-31

Category : Medical

ISBN : 111814564X

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Book Description

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes the physico-chemical properties and biological effects of excipients Discusses chemical classes, safety and toxicity, and formulation Addresses recent efforts in the standardization and harmonization of excipients



Profiles of Drug Substances, Excipients and Related Methodology

Author : Harry G. Brittain

Publisher : Academic Press

Page : 399 pages

File Size : 37,70 MB

Release : 2011-07-15

Category : Science

ISBN : 0123877024

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Book Description

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. Presents comprehensive reviews covering all aspects of drug development and formulation of drugs Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others Meets the information needs of the drug development community



Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems

Author : Ashok Katdare

Publisher : CRC Press

Page : 474 pages

File Size : 23,92 MB

Release : 2006-07-28

Category : Medical

ISBN : 1420004131

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Book Description

To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.



Polyvinylpyrrolidone Excipients for Pharmaceuticals

Author : Volker Bühler

Publisher : Springer Science & Business Media

Page : 272 pages

File Size : 19,84 MB

Release : 2005

Category : Medical

ISBN : 9783540234128

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Book Description

The book describes the properties, analytical methods and the applications of different polyvinylpyrrolidone excipients (povidone, crospovidone, copovidone etc.) for use in pharmaceutical preparations. This group of excipients is one of the most important excipients used in modern technology to produce drugs. The book is intended for all persons working in the research, development and quality control of drugs. It gives a survey of all applications in solid, liquid and semisolid dosage forms including many drug formulation examples and more than 600 references to the literature.



Excipient Applications in Formulation Design and Drug Delivery

Author : Ajit S Narang

Publisher : Springer

Page : 700 pages

File Size : 33,50 MB

Release : 2015-10-07

Category : Medical

ISBN : 3319202065

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Book Description

In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications. This book presents a concise summary of relevant scientific and mechanistic information that can aid the use of excipients in formulation design and drug delivery applications. Each chapter is contributed by chosen experts in their respective fields, which affords truly in-depth perspective into a spectrum of excipient-focused topics. This book captures current subjects of interest – with the most up to date research updates – in the field of pharmaceutical excipients. This includes areas of interest to the biopharmaceutical industry users, students, educators, excipient manufacturers, and regulatory bodies alike.



Analytical Profiles of Drug Substances and Excipients

Author :

Publisher : Academic Press

Page : 633 pages

File Size : 16,22 MB

Release : 1996-08-30

Category : Science

ISBN : 0080861199

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Book Description

Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Edited by the Associate Director of Analytical Research and Development for the AmericanAssociation of Pharmaceutical Scientists, Analytical Profiles of Drug Substances and Excipients brings this information together into one source. The scope of the series has recently been expanded to include profiles of excipient materials.



Pharmaceutical Excipients

Author : David E. Bugay

Publisher : CRC Press

Page : 688 pages

File Size : 41,37 MB

Release : 1999-02-23

Category : Medical

ISBN : 9780824793739

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Book Description

Meeting the need for a hands-on guide elucidating the role of molecular spectroscopy in the physical characterization of pharmaceutical solids, two experts from the industry gather theoretical discussions of infrared, Raman, and nuclear magnetic resonance spectroscopy. They provide recommendations on spectral data acquisition techniques and include 600 spectra for 300 of the most commonly used excipients. Complete with references, equations, tables, and a CAS registry number index, the book covers the drug development process, including chemical identification of substances, investigative studies, competitor analysis, problem solving activities, reproduction of spectral data, and more.



Handbook of Pharmaceutical Excipients

Author : Ainley Wade

Publisher : Pharmaceutical Press

Page : 688 pages

File Size : 19,40 MB

Release : 1994

Category : Medical

ISBN :

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Book Description

This is the second edition of a work on pharmaceutical excipients. It has been expanded and revised to include 203 monographs for pharmacopoeital and non-pharmacopoeital excipients. The appendices include a substantial suppliers' directory. All the physical properties of excipients are included.