The Publisher


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William Richard Gowers 1845-1915


Book Description

Sir William Richard Gowers was one of the pre-eminent clinical neurologists of the nineteenth century. Co-authored by one of Dr Gowers' descendents and two leading neurologists, this book is the definitive reference work on the life of one of the founding fathers of neurology.




Willis's Current notes


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Saving Lives, Buying Time


Book Description

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.







The Journal of Henry David Thoreau, 1837-1861


Book Description

Henry David Thoreau’s Journal was his life’s work: the daily practice of writing that accompanied his daily walks, the workshop where he developed his books and essays, and a project in its own right—one of the most intensive explorations ever made of the everyday environment, the revolving seasons, and the changing self. It is a treasure trove of some of the finest prose in English and, for those acquainted with it, its prismatic pages exercise a hypnotic fascination. Yet at roughly seven thousand pages, or two million words, it remains Thoreau’s least-known work. This reader’s edition, the largest one-volume edition of Thoreau’s Journal ever published, is the first to capture the scope, rhythms, and variety of the work as a whole. Ranging freely over the world at large, the Journal is no less devoted to the life within. As Thoreau says, “It is in vain to write on the seasons unless you have the seasons in you.”




Pain Management and the Opioid Epidemic


Book Description

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.