Phytochemicals and Phytopharmaceuticals


Book Description

Shahidi (biochemistry, Memorial U. of Newfoundland) and Ho (food science, Rutgers U.) present a monograph from an international group of scientists that contains 37 papers discussing plant bioactives in a varied range of research areas. Specific topics include variables affecting the phytochemical contents of garlic and their health benefits, the role of flavonols and anthocyanins from fruits and vegetables in cancer prevention, and antioxidative and cytotoxic components of highbush blueberry. Annotation copyrighted by Book News, Inc., Portland, OR




Anti-inflammatory Nutraceuticals and Chronic Diseases


Book Description

This comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in various chronic diseases. Food and Drug Administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. This means that there is enormous potential for dietary agents that can modulate inflammatory pathways in humans. Leading experts describe the latest research on the role of anti-inflammatory nutraceuticals in preventing and treating chronic diseases.




Phytomedicine


Book Description

Phytomedicine: A Treasure of Pharmacologically Active Products from Plants aims to present updated knowledge of plant-based medicines in terms of their research and development, production, and utilization, from the viewpoint of sustainability and by using the latest technologies. The book explores different phytometabolites on a mass scale, coupled with the efficacy, performance and applicability on target organisms to treat curable and fatal diseases. Readers will find a coherent package of phytotherapeutic information regarding inclusive assortment of research based, scientific amplitude of metabolites from the plant world encompassing various action plans. Information is presented sequentially regarding phytochemistry, biological activity and the serviceable aspects of bioactive compounds. The book also addresses various advancements and achievements of novel drugs from plants using molecular and enzymatic activities, and various technological tools in an ecofriendly fashion. - Discusses phytotherapeutic properties for a wide range of medical conditions, including anti-pyretic, anti-infective, anti-malarial, Anti-AIDS, anti-diabetic, anti-cancerous, immune-modulatory applications - Includes a discussion of synergistic effects of formulations and antagonistic drug interactions - Addresses advancements and achievements of novel plant-based drugs using molecular, enzymatic activities and various technological tools in an eco-friendly fashion




Functional and Preservative Properties of Phytochemicals


Book Description

Functional and Preservative Properties of Phytochemicals examines the potential of plant-based bioactive compounds as functional food ingredients and preservative agents against food-spoiling microbes and oxidative deterioration. The book provides a unified and systematic accounting of plant-based bioactive compounds by illustrating the connections among the different disciplines, such as food science, nutrition, pharmacology, toxicology, combinatorial chemistry, nanotechnology and biotechnological approaches. Chapters present the varied sources of raw materials, biochemical properties, metabolism, health benefits, preservative efficacy, toxicological aspect, safety and Intellectual Property Right issue of plant-based bioactive compounds. Written by authorities within the field, the individual chapters of the book are organized according to the following practical and easy to consult format: introduction, chapter topics and text, conclusions (take-home lessons), and references cited for further reading. - Provides collective information on recent advancements that increase the potential use of phytochemicals - Fosters an understanding of plant-based dietary bioactive ingredients and their physiological effects on human health at the molecular level - Thoroughly explores biotechnology, omics, and bioinformatics approaches to address the availability, cost, and mode of action of plant-based functional and preservative ingredients




Advances in Pharmaceutical Biotechnology


Book Description

This book explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical uses. The foundations of pharmaceutical biotechnology lie mainly in the capability of plants, microorganism, and animals to produce low and high molecular weight compounds useful as therapeutics. Pharmaceutical biotechnology has flourished since the advent of recombinant DNA technology and metabolic engineering, supported by the well-developed bioprocess technology. A large number of monoclonal antibodies and therapeutic proteins have been approved, delivering meaningful contributions to patients’ lives, and the techniques of biotechnology are also a driving force in modern drug discovery. Due to this rapid growth in the importance of biopharmaceuticals and the techniques of biotechnologies to modern medicine and the life sciences, the field of pharmaceutical biotechnology has become an increasingly important component in the education of pharmacists and pharmaceutical scientists. This book will serve as a complete one-stop source on the subject for undergraduate and graduate pharmacists, pharmaceutical science students, and pharmaceutical scientists in industry and academia.




Phytotechnology


Book Description

Herbal products have traditionally been used in several industrial sectors and have gained a notable reputation in recent years due to the current trend in society, which seeks natural, healthier, and more sustainable products. The processing of these products, however, is multiplex but important for the production of a high-quality standardised product. Phytotechnology: A Sustainable Platform for the Development of Herbal Products highlights the complex, multidisciplinary process of phytopharmaceutical technology used to create herbal remedies. Organised into four parts, various experts in the field clearly and objectively address the fundamental and technological concepts involved in the manufacturing of high-quality herbal products. Additional Features Emphasises how herbal products have traditionally been used in several industrial sectors, including pharmaceutical science, food, cosmetics, chemical engineering, and agroindustry Provides a much-needed update of the current information regarding phytopharmaceutical technology and focuses on industrial applications Written using a multidisciplinary approach, to include all subjects involved in the processing of herbal products The information presented is valuable reference material for professionals of different specialties who wish to enter this fascinating and innovative area.




Database of Biologically Active Phytochemicals & Their Activity


Book Description

Database of Biologically Active Phytochemicals and Their Activities presents an alphabetical tabulation of some 3,000 biologically active phytochemicals (elements and compounds) from higher plants. The data includes at least one and in some cases as many as 25 biological activities for each phytochemical. The database also provides data on effective dose, inhibitory concentrations, and lethal and/or toxic doses. Entries after 1990 indicate the source of the data. Database of Biologically Active Phytochemicals and Their Activities makes it possible to locate the concentration of many compounds in plants and compare this data with dosage information to calculate how much of a given plant food it would take to cause lethality, antioxidant activity, hypoglycemic activity, or artemicidal activity. Using WordPerfect (TM) 5.1's search function, you can find compounds by entering a key word in their name (e.g., choline or salicyl-), locate all compounds with a given activity (e.g., hypotensive), or list all compounds for which ED50 data is entered or reported.




Preparation of Phytopharmaceuticals for the Management of Disorders


Book Description

Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals, nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals, their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful. - Includes the history and current highlights in phytomedicine, along with classifications of crude drugs, herbal drug technologies and herbal cosmeticology - Provides detailed information on herbal remedies and toxicity, traditional and alternative systems of medicine, and applications of microbiology and biotechnology in drug discovery - Discusses the nutritional and health benefits of nutraceuticals and how they help in the management and treatment of metabolic diseases




Phytochemistry of Medicinal Plants


Book Description

Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.




Immunity and Inflammation in Health and Disease


Book Description

Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here. - Conceptualizes the key features in natural products which can boost immune function and immune health - Explains the intricate mechanistic aspects and balance behind immune health - Presents the pathophysiology of several diseases associated with immune system disruption