Polymeric Nanomaterials in Nanotherapeutics


Book Description

Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. - Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies - Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes - Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations




Encyclopedia of Polymeric Nanomaterials


Book Description

Over the last few years, nanoscience and nanotechnology have been the focus of significant research attention, both from academia and industry. This sustained focus has in-turn driven the interdisciplinary field of material science research to the forefront of scientific inquiry through the creation and study of nanomaterials. Nanomaterials play an important role in the development of new materials as they can be used to influence and control physical properties and specific characteristics of other materials. Nanostructured materials that have been created include nanoparticles, nanocapsules, nanoporous materials, polymer multi-layers to name a few. These are increasingly used across applications as diverse as automotive, environment, energy, catalysis, biomedical, pharmaceutical, and polymer industries. The Encyclopedia of Polymeric Nanomaterials (EPN) intends to be a comprehensive reference work on this dynamic field studying nanomaterials within the context of the relationship between molecular structure and the properties of polymeric materials. Alphabetically organized as an encyclopedic Major Reference Work, EPN will cover the subject along multiple classification axes represented by name, source, properties, function, and structures or even processes, applications and usage. The underlying themes of the encyclopedia has been carefully identified to be based not just on material-based and function-based representation but also on structure- and process-based representation. The encyclopedia will have an exclusive focus on polymeric nanomaterials (for e.g., nanoceramics, nanocomposites, quantum dots, thin films) and will be a first of its kind work to have such an organization providing an overview to the concepts, practices and applications in the field. The encyclopedia intends to cover research and development work ranging from the fundamental mechanisms used for the fabrication of polymeric nanomaterials to their advanced application across multiple industries.




Polymer Science and Nanotechnology


Book Description

Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest and utility for novel applications, such as hydrogels, natural polymers, smart polymers and polymeric biomaterials. The second part of the book examines essential techniques in nanotechnology, with an emphasis on the utilization of advanced polymeric materials in the context of nanoscience. Throughout the book, chapters are prepared so that materials and products can be geared towards specific applications. Two chapters cover, in detail, major application areas, including fuel and solar cells, tissue engineering, drug and gene delivery, membranes, water treatment and oil recovery. - Presents the latest applications of polymers and polymeric nanomaterials, across energy, biomedical, pharmaceutical, and environmental fields - Contains detailed coverage of polymer nanocomposites, polymer nanoparticles, and hybrid polymer-metallic nanoparticles - Supports an interdisciplinary approach, enabling readers from different disciplines to understand polymer science and nanotechnology and the interface between them




Polymeric Nanomaterials


Book Description

The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences. Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest. Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies. VOLUME 10 - Polymeric Nanomaterials




Nanomaterials and Polymer Nanocomposites


Book Description

Nanomaterials and Polymer Nanocomposites: Raw Materials to Applications brings together the most recent research in nanoparticles and polymer nanocomposites for a range of applications. The book's coverage is comprehensive, starting with synthesis techniques, then moving to characterization and applications of several different classes of nanomaterial and nanoparticle in nanocomposites. By presenting different nanomaterials, such as metal and metal oxides, clay and POSS, carbon nanotubes, cellulose and bio-based polymers in a structured manner, the book enables an efficient comparison of properties and capabilities for these advanced materials, making it relevant both for researchers in an academic environment and also industrial R&D. This book is particularly distinctive because it centers on the raw materials on which the nanocomposites are based, the biological properties of the range of materials discussed, and the environmental and economic considerations of different polymer systems. - Presents a thorough, up-to-date review of the latest advances and developments in the field of nanomaterials and polymer nanocomposites, with a particular focus on raw materials - Includes comprehensive coverage from historical backgrounds, synthesis techniques, characterization, and a detailed look at new and emerging applications for polymer nanocomposites - Provides a range of different material classes, including metal and metal oxides, biopolymers, graphene and cellulose, among others




Biopolymeric Nanomaterials


Book Description

Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric nanomaterials refer to biocompatible nanomaterials, consisting of biopolymers, such as protein (silk, collagen, gelatin, ß-casein, zein, and albumin), protein-mimicked polypeptides and polysaccharides (chitosan, alginate, pullulan, starch, and heparin). Biopolymeric nanomaterials may be used as i) delivery systems for bioactive compounds in food application, (ii) for delivery of therapeutic molecules (drugs and genes), or for (iii) tissue engineering. Provides information on the design concepts and synthesis of biopolymeric nanomaterials in biomedical and industrial applications Highlights the major properties and processing methods for biopolymeric nanomaterials Assesses the major challenges of producing biopolymeric nanomaterials on an industrial scale




Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics


Book Description

Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. - Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy - Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer - Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles




Polymers and Nanomaterials for Gene Therapy


Book Description

Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy. - Explores current challenges in the research of genetic diseases - Discusses polymers for gene therapy and their function in designing advanced materials - Provides examples of organic and inorganic nanomaterials for gene therapy - Includes labeling, targeting, and assays - Looks at characterization, physico-(bio)chemical properties, and applications




Polymer Composites with Functionalized Nanoparticles


Book Description

Polymer Composites with Functional Nanoparticles: Synthesis, Properties, and Applications reviews the latest research in the area of polymer nanocomposites and functionalized nanoparticles, providing an introduction for those new to the field, and supporting further research and development. The book helps researchers and practitioners better understand the key role of nanoparticle functionalization for improving the compatibility of inorganic metallic nanomaterials with organic polymers, and for the fabrication of nanostructured materials with special properties. A range of nanoparticles, such as carbon nanotubes are covered, along with descriptions of the methods of functionalization to support better compatibility with polymer matrices. The book also discusses the various applications of this technology, including uses in electronics and the medical and energy industries. - Summarizes the latest research in functionalized nanoparticles for modification of polymer matrices, providing a valuable platform for further research - Includes functionalization of a range of nanoparticles for incorporation into nanocomposites, including carbon nanotubes, graphene, gold and silver, silica and clay - Provides detailed coverage of application areas, including energy, electronics, biomedical applications, and end-of-life considerations




Handbook of Materials for Nanomedicine


Book Description

In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of polymeric nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. Beginning with the combinatorial approach for polymer design, it discusses star-shaped amphiphilic polymers, self-assembling polymer–drug conjugates, amphiphilic dendrimers, dendrimer nanohybrids, sustainable green polymeric nanoconstructs, chitosan-based nanogels, and multifunctional hybrid nanogels. The book provides all available information about these materials and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully.