The Handbook of Medicinal Chemistry


Book Description

Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.




Practical Pharmaceutical Chemistry


Book Description

This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.




Pharmaceutical Analysis


Book Description

This manual consists of different chapters dealing with the detailed information of pharmaceutical analytical techniques and organized according to the type of titration or techniques. Each technique is explained along with the experiments.This manual will suffice the requirements of academics and research




Handbook of Practical Pharmaceutical Organic, Inorganic and Medicinal Chemistry


Book Description

This book described about the concept and procedure involved in various important inorganic laboratory experiments, with all the possible explanation. This book explains about the detail’s steps involved the identification of unknown chemical compounds, synthesis of numbers of drugs and intermediates with reaction mechanisms and calculation. The assay methods of various drugs and calculation of drug content also included. This book covers the entire inorganic, organic and medicinal chemistry experiments as per the Pharmacy council of India’s B. Pharm and Pharm D syllabus




A Practical Book of Pharmaceutical Inorganic Chemistry


Book Description

"ABOUT THE BOOK: This book, ""A Practical Book of Pharmaceutical Inorganic Chemistry,"" was written by six different authors in accordance with the B.Pharm first-semester PCI curriculum. The primary purpose of this book is to provide readily accessible methods and procedures for conducting pharmaceutical inorganic chemistry practicals in the first semester of B. Pharm, with a focus on facilitating subject comprehension. It contains 18 experiments based strictly on the PCI curriculum, as well as various laboratory safety measures as the first section of the book. It also contains experimental procedures and the fundamentals of various limit tests, such as the Limit test for Chlorides, the Limit test for Sulphates, the Limit test for Iron, the Limit test for Heavy metals, the Limit test for Lead, and the Limit test for Arsenic. Other experiments include tests for the identification of various inorganic compounds listed in the curriculum, tests for purity, and the preparation of inorganic pharmaceuticals. "




Practical Handbook of Pharmaceutical Instrumental Analysis


Book Description

This book described about the concept and procedure involved in instrumental analytical techniques, with all the possible explanation. This book clearly explains the post experiment calculations with the performed experiments, that will be helpful to the students to understand and obtain the accurate and precise results. This book covers the entire Instrumental analytical experiments as per the Pharmacy council of India’s B. Pharm and Pharm D syllabus.




A Practical Book of Pharmaceutical Organic Chemistry-II


Book Description

This book, “”A Practical Book of Pharmaceutical Organic Chemistry-II,”” was written by 07 different authors in accordance with the B.Pharm thirds-semester PCI curriculum. The primary purpose of this book is to provide readily accessible methods and procedures for conducting pharmaceutical Organic chemistry practicals in the 3rd semester of B. Pharm, with a focus on facilitating subject comprehension. It contains 17 experiments based strictly on the PCI curriculum containing introductory part on Recrystallisation and Steam distillation technique, following by experimental procedures of various organic compounds mentioned in the PCI Syllbus ”




Comprehensive Practical Manual of Pharmaceutical Chemistry


Book Description

The edition of Comprehensive Practical Manual of Pharmaceutical Chemistry is authored in simple and comprehensive style according to PCI (Pharmacy Council of India) syllabus to meet the specific needs of the pharmacy students. It provides comprehensive yet concise chemistry for D.Pharmacy, B.Pharmacy, M.Pharmacy and Pharm D students. The main objective of this manual is to attract students to learn the basic theories of pharmaceutical chemistry thus the manual is aimed to enrich the inadequancy in teaching and learning of pharmaceutical chemistry by providing enormous information. The style of presentation of this manual is such that it not only gives deeper understanding of the subject but also will help the beginners to overcome the fright of the subject. The manual gives concise and pointwise information required during practicals in single book and eliminates the need of too many reference books during practicals. The manual authored in simple,lucid and easy language.




Measuring Elemental Impurities in Pharmaceuticals


Book Description

Recent regulations on heavy metal testing have required the pharmaceutical industry to monitor a suite of elemental impurities in pharmaceutical raw materials, drug products and dietary supplements. These new directives s are described in the new United States Pharmacopeia (USP) Chapters , , and , together with Q3D, Step 4 guidelines for elemental impurities, drafted by the ICH (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use), a consortium of global pharmaceutical associations, including the European Pharmacopeia (Ph.Eur.), the Japanese Pharmacopeia (JP) and the USP. This book provides a complete guide to the analytical methodology, instrumental techniques and sample preparation procedures used for measuring elemental impurities in pharmaceutical and nutraceutical materials. It offers readers the tools to better understand plasma spectrochemistry to optimize detection capability for the full suite of elemental PDE (Permitted Daily Exposure) levels in the various drug delivery categories. Other relevant information covered in the book includes: The complete guide to measuring elemental impurities in pharmaceutical and nutraceutical materials. Covers heavy metals testing in the pharmaceutical industry from an historical perspective. Gives an overview of current USP Chapters and and ICH Q3D Step 4 Guidelines. Explains the purpose of validation protocols used in Chapter , including how J-values are calculated Describes fundamental principles and practical capabilities of ICP-MS and ICP-OES. Offers guidelines about the optimum strategy for risk assessment Provides tips on how best to prepare and present your data for regulatory inspection. An indispensable resource, the fundamental principles and practical benefits of ICP-OES and ICP-MS are covered in a reader-friendly format that a novice, who is carrying out elemental impurities testing in the pharmaceutical and nutraceutical communities, will find easy to understand.