Practical Pharmaceutical Chemistry


Book Description

This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.







Pharmaceutical Chemistry - Ii


Book Description

Introduction. Centrak Nervous System Stimulants. Antidepressants and Antinxienty Agent (Anxiolytic). Antipsychotic Agents and Hallucinogens. General Anaestetics. Hypnotics and Sedatives. Skeletal Muscle Relaxants. Tranquilizing Agents. Anticonvulsant Drugs. Analgesics (Narcotcs). Anpyertic Analgesics. Nonsteroidal Anti- Inflammatory Agents. Adrenergic Agents. Adrenergic Blocking Agents. Cardiovascular Agents. Histamines & Antihistaminic Agents. antitussives & Expectorants. Coagulants and Anticoagulants




Pharmaceutical Chemistry


Book Description

Discusses the chemistry of important pharmaceutical organic compounds, covering their nomenclature, chemical structure, uses, and physical and chemical properties. It also includes stability and storage conditions, official pharmaceutical preparations, and brand names of important drugs.The book is divided into two sections. The sections emphasize both the theoretical and practical aspects of the drugs. The entire text is covered in 36 chapters, and each chapter covers all the topics in a cogent and lucid style to help the reader grasp the information quickly and easily. The book is a complete treatise on pharmaceutical drugs. It is an essential reading for students and teachers of diploma in pharmacy.




Introduction to Pharmaceutical Analytical Chemistry


Book Description

The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals. This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject Examines various analytical techniques commonly used in pharmaceutical laboratories Provides practice problems, up-to-date practical examples and detailed illustrations Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.




The Practice of Medicinal Chemistry


Book Description

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com




Practical Pharmaceutical Engineering


Book Description

A practical guide to all key the elements of pharmaceuticals and biotech manufacturing and design Engineers working in the pharmaceutical and biotech industries are routinely called upon to handle operational issues outside of their fields of expertise. Traditionally the competencies required to fulfill those tasks were achieved piecemeal, through years of self-teaching and on-the-job experience—until now. Practical Pharmaceutical Engineering provides readers with the technical information and tools needed to deal with most common engineering issues that can arise in the course of day-to-day operations of pharmaceutical/biotech research and manufacturing. Engineers working in pharma/biotech wear many hats. They are involved in the conception, design, construction, and operation of research facilities and manufacturing plants, as well as the scale-up, manufacturing, packaging, and labeling processes. They have to implement FDA regulations, validation assurance, quality control, and Good Manufacturing Practices (GMP) compliance measures, and to maintain a high level of personal and environmental safety. This book provides readers from a range of engineering specialties with a detailed blueprint and the technical knowledge needed to tackle those critical responsibilities with confidence. At minimum, after reading this book, readers will have the knowledge needed to constructively participate in contractor/user briefings. Provides pharmaceutical industry professionals with an overview of how all the parts fit together and a level of expertise that can take years of on-the-job experience to acquire Addresses topics not covered in university courses but which are crucial to working effectively in the pharma/biotech industry Fills a gap in the literature, providing important information on pharmaceutical operation issues required for meeting regulatory guidelines, plant support design, and project engineering Covers the basics of HVAC systems, water systems, electric systems, reliability, maintainability, and quality assurance, relevant to pharmaceutical engineering Practical Pharmaceutical Engineering is an indispensable “tool of the trade” for chemical engineers, mechanical engineers, and pharmaceutical engineers employed by pharmaceutical and biotech companies, engineering firms, and consulting firms. It also is a must-read for engineering students, pharmacy students, chemistry students, and others considering a career in pharmaceuticals.




A Textbook Of Pharmaceutical Inorganic Chemistry


Book Description

The study of elements and the compounds they form is referred to as inorganic chemistry. Organic chemistry, on the other hand, is concerned with carbon and the compounds it forms. However, there is a lot of crossovers between organic and inorganic, thus the two categories are not completely separate from one another. The book's key features include an overview of general elements and the relevance of those aspects, with a focus on the applications in the pharmaceutical field. is a standard textbook that is often used for an introductory level inorganic chemistry undergraduate course. It provides a complete pedagogical framework to assist students with understanding essential concepts. This book gives a decent introduction to the topic; explains a variety of inorganic compounds as well as the minimal chemical facts and ideas that are required to comprehend current inorganic chemistry; offers a good overview of the subject. provides an advanced and in-depth descriptive treatment of all of the official compounds featured, with a significant emphasis on the production, characteristics, assay, and medicinal uses of the compounds. The book “A Textbook of Pharmaceutical Inorganic Chemistry” is prepared in an exhaustive fashion and includes facts that have been brought up to date about the subjects that are covered in the curriculum. The book Covers the fundamentals of basic inorganic chemistry that are necessary for undergraduate pharmacy students, while students of chemistry, biology, and other relevant subjects will also find this book to be fascinating and informative.







ORGANIC CHEMISTRY, SECOND EDITION


Book Description

The second edition of the book continues to offer a range of pedagogical features maintaining the balanced approach of the text. The attempts have been made to further strengthen the conceptual understanding by introducing more ideas and a number of solved problems. Comprehensive in approach, this text presents a rigorous treatment of organic chemistry to enable undergraduate students to learn the subject in a clear, direct, easily understandable and logical manner. Presented in a new and exciting way, the goal of this book is to make the study of organic chemistry as stimulating, interesting, and relevant as possible. Beginning with the structures and properties of molecules, IUPAC nomenclature, stereochemistry, and mechanisms of organic reactions, proceeding next to detailed treatment of chemistry of hydrocarbons and functional groups, then to organometallic compounds and oxidation–reduction reactions, and ending with a study of selected topics (such as heterocyclic compounds, carbohydrates, amino acids, peptides and proteins, drugs and pesticides, dyes, synthetic polymers and spectroscopy), the book narrates a cohesive story about organic chemistry. Transitions between topics are smooth, explanations are lucid, and tie-ins to earlier material are frequent to maintain continuity. The book contains over 500 solved problems from simple to really challenging ones with suitable explanations. In addition, over 275 examples and solved problems on IUPAC nomenclature, with varying levels of difficulty, are included. About Some Key Features of the Book • EXPLORE MORE: Four sets of solved problems provide in-depth knowledge and enhanced understanding of some important aspects of organic chemistry. • MINI ESSAYS: Three small essays present interesting write-ups to provide students with introductory knowledge of chemistry of natural products such as lipids, terpenes, alkaloids, steroids along with nucleic acids and enzymes. • NOTABILIA: Twenty-two ‘notabilia boxes’ interspersed throughout the text highlight the key aspects of related topics, varying from concepts of chemistry to the chemistry related to day-to-day life. • STRUCTURES AND MECHANISMS NOT IN ORDER: Cites examples of common errors made by students while drawing structural formulae and displaying arrows in reaction mechanisms and helps them to improve on language of organic chemistry by teaching appropriate drawings and their significance. • GLOSSARY: Includes ‘Name reactions’, ‘Reagents’, and some important terms for quick revision by students. Clearly written and logically organized, the authors have endeavoured to make this complex and important branch of science as easy as possible for students to learn from and for teachers to teach from.