Advances in Calcium Phosphate Biomaterials


Book Description

Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia




Calcium Orthophosphates


Book Description

Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophospha




Calcium Orthophosphate-Based Bioceramics and Biocomposites


Book Description

Reflecting the advances made in recent years, this is a comprehensive overview of calcium orthophosphates for bioceramics and biocomposites with a special focus on the detailed description of all those available, including their biological and geological occurrence, preparation, chemical composition, structure-property relationships and applications. In particular, the book discusses the suitability of these orthophosphates for biomedical applications and their use as bone grafts in surgery and medicine. The result is a useful reference for researchers with an academic, medical or commercial background.




Bioceramics and Biocomposites


Book Description

Provides comprehensive coverage of the research into and clinical uses of bioceramics and biocomposites Developments related to bioceramics and biocomposites appear to be one the most dynamic areas in the field of biomaterials, with multiple applications in tissue engineering and medical devices. This book covers the basic science and engineering of bioceramics and biocomposites for applications in dentistry and orthopedics, as well as the state-of-the-art aspects of biofabrication techniques, tissue engineering, remodeling, and regeneration of bone tissue. It also provides insight into the use of bionanomaterials to create new functionalities when interfaced with biological molecules or structures. Featuring contributions from leading experts in the field, Bioceramics and Biocomposites: From Research to Use in Clinical Practice offers complete coverage of everything from extending the concept of hemopoietic and stromal niches, to the evolution of bioceramic-based scaffolds. It looks at perspectives on and trends in bioceramics in endodontics, and discusses the influence of newer biomaterials use on the structuring of the clinician’s attitude in dental practice or in orthopedic surgery. The book also covers such topics as biofabrication techniques for bioceramics and biocomposites; glass ceramics: calcium phosphate coatings; brain drug delivery bone substitutes; and much more. Presents the biggest trends in bioceramics and biocomposites relating to medical devices and tissue engineering products Systematically presents new information about bioceramics and biocomposites, developing diagnostics and improving treatments and their influence on the clinicians' approaches Describes how to use these biomaterials to create new functionalities when interfaced with biological molecules or structures Offers a range of applications in clinical practice, including bone tissue engineering, remodeling, and regeneration Delineates essential requirements for resorbable bioceramics Discusses clinical results obtained in dental and orthopedic applications Bioceramics and Biocomposites: From Research to Use in Clinical Practice is an excellent resource for biomaterials scientists and engineers, bioengineers, materials scientists, and engineers. It will also benefit mechanical engineers and biochemists who work with biomaterials scientists.




Hydroxyapatite (HAp) for Biomedical Applications


Book Description

Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. - Reviews the important properties of hydroxyapatite as a biomaterial - Considers a range of specific forms of the material and their advantages - Reviews a range of specific medical applications for this important material




Interface Oral Health Science 2016


Book Description

This volume broadens understanding of dentistry and promotes interdisciplinary research across a wide range of related fields, based on the symposium entitled "Innovative Research for Biosis-Abiosis Intelligent Interface 2016". It aims to create highly functional and autonomic intelligent interface by combining highly functional interface science with the technology of an evaluation and a control at the interface, with the various topics of biomaterials, innovation for oral science and application, regenerative oral science, and medical engineering. Since 2002, the Tohoku University Graduate School of Dentistry has hosted "Interface Oral Health Science" several times as the main theme of dental research in the twenty-first century, and this is the sixth proceedings of the symposiums following the ones in 2005, 2007, 2009, 2011, and 2014.This book benefits not only dental scientists but also other health scientists including medical physicians and pharmacologists, material scientists, engineers, and any scientist who is involved in variety of disciplines. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.




Calcium phosphate Ceramics - Bioresorbable Polymer Composite Biomaterials


Book Description

In the past several years, the accent of a number of scientific researches in the countries of the European Union, USA and Japan was focused on the field of biomaterials. Having the direct influence on the quality and longevity of human life, these researches receive significant funding. The bone tissue is an especially interesting subject of scientific research, as much for the frequent osteoporosis as for the formative nature of organism. Natural bone is mostly composed of nanostructural calcium phosphate (hydroxyapatite). Whether bone trauma was caused artificially or through illness, the number of reconstructions increases every year worldwide and thus the monetary investment into this field. Until now, numerous kinds of biomaterials were used for this purpose. Development of equipment and progress in characterization techniques and devices enabled an exponential development of new and advanced biomaterials’ synthesis. Many qualitative and quantitative content concepts and the organization of biomaterials on all structural levels were taken from nature. Biomaterials for the reconstruction of bone tissue, very similar to human tissue, in the form of composite blocks, injectable cements, nano-fillers, etc., were produced this way. Synthesis of calcium phosphate and hydroxyapatite, as well as the composite for the reconstruction of bone tissue, has been a significant research field of a section of Advanced Materials and Processes Department of the Institute of Technical Sciences of the Serbian Academy of Sciences and Arts (ITS SASA) from Belgrade for a number of years. Apart from a number of published scientific papers in leading international journals, lectures presented at the leading universities worldwide, several PhD dissertations defended at various faculties in the land, and several domestic patents, researchers have established the basis of the technological procedure and the production of small series of various products developed in their laboratory. These researches have very wide aspect of significance – from fundamental, scientific to specifically applicative. It can be said that these researches include everything from synthesis, processing, characterization to their application. This book contains 44 papers published in SCI journals since 1999 until May 2007. It is divided into five sections and each assembles the most important results in the specific area: I Synthesis and Processing, II Synthesis, Properties and Characterization of Biomaterials, III Mechanical Properties and Modelling of Biomaterials, IV Biological Evaluation of Biomaterials, V Behaviour of Biomaterials under Radiation Field.




Octacalcium Phosphate Biomaterials


Book Description

Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. - Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties - Presents the clinical potential of octacalcium phosphate biomaterials - Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration




Bone Tissue Engineering


Book Description

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t




Octacalcium Phosphate


Book Description

The chemistry, structure and biological importance of octacalcium phosphate (OCP) are thoroughly discussed in this volume, which covers a wide scope of topics relevant to the field of calcium phosphates in general. The first chapter reviews the structures of OCP and other important calcium phosphates. It is followed by a description of the mimicry of OCP growth in vivo using in vitro model systems and an extensive review of OCP in biological systems. The remarkable ability of OCP to incorporate biologically relevant organic carboxylates into its structure is also discussed, along with the solubility and surface properties of calcium phosphate salts, and amorphous calcium phosphate and its relationship to OCP. The last chapter centers on the emerging technology of calcium phosphate cements as bone defect repair materials. The book provides in-depth, up-to-date information to all scientists studying calcium phosphate chemistry, biomineralization, pathological calcification, dental caries, biomaterials, and recovery of environmental phosphorus.