Principles of Cellular, Molecular, and Developmental Neuroscience


Book Description

The field of cellular, molecular, and developmental neuroscience repre sents the interface between the three large, well established fields of neu roscience, cell biology, and molecular biology. In the last 10 to 15 years, this new field has emerged as one of the most rapidly growing and exciting subdisciplines of neuroscience. It is now becoming possible to understand many aspects of nervous system function at the molecular level, and there already are dramatic applications of this information to the treatment of nervous system injury, disease, and genetic disorders. Moreover, there is great optimism that new strategies will emerge soon as a result of the explosion of information. This book was written to introduce students to the major issues, ex perimental strategies, and current knowledge base in cellular, molecular, and developmental neuroscience. The concept for the book arose from a section of an introductory neuroscience course given to first-year medical students at the University of Virginia School of Medicine. The text pre sumes a basic, but not detailed, understanding of nervous system orga nization and function, and a background in biology. It is intended as an appropriate introductory text for first-year medical students or graduate students in neuroscience, neurobiology, psychobiology, or related pro grams;··and for advanced undergraduate students with appropriate back ground in biology and neuroscience. While some of the specific information presented undoubtedly will be outdated rapidly, the "gestalt" of this emerging field of inquiry as presented here should help the beginning stu dent organize new information.




Basic Neurochemistry


Book Description

Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475




Principles of Neurobiology


Book Description

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.




Principles of Neural Development


Book Description




Developmental Neurobiology


Book Description

This consistent and well-illustrated text is an up-to-date survey of cellular and molecular events contributing to the assembly of the vertebrate nervous system. Chapters include a mixture of historical content and descriptions from literature that best illustrate specific aspects of development.




Development of the Nervous System


Book Description

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. - Updates information including all the new developments made in the field since the first edition - Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated







Functional Neuroscience


Book Description

An integrated textbook of medical neuroscience, this book coherently presents the anatomy, physiology, and biochemistry of the human nervous system. The neuroanatomy is presented in a way that is integrated with a modern presentation of cellular neurophysiological systems, neuroscience, and cellular, molecular, and developmental neuroscience. Clinical correlations are provided wherever appropriate.




Alcohol and Neurobiology


Book Description

The neurological consequences of alcohol abuse need additional research concentrating on prevention and treatment. Public attention and research efforts are being driven by an ever- increasing understanding of the problems and magnitude of alcohol on neurological development. The 10 million alcohol-abusing adults, along with unborn children exposed to alcohol in utero, cost the people of the U.S. more than $100 billion in lost wages, health care, theft, damaged mental functions, and shortened life span. An intimate, detailed knowledge of the effects of alcohol on the biochemical reactions and neurological changes is critical in preventing or treating abuse. We must study the mechanisms of ethanol's effects on the neurological system at a cellular and systematic level to understand its action. These include modifications of hormonal regulation and production with its major functional consequences. Brain development including its cells are a major focus and emphasis of this volume. The progress of research over the past decade is encouraging as we begin to summarize and evaluate in detail advances in understanding changes in the brain's biochemistry and physiology caused by ethanol. This information will assist the researcher, clinician, and student in comprehending the complex changes caused by direct and indirect effects of single drugs at the cellular level.




Brain Plasticity and Behavior


Book Description

There are few books devoted to the topic of brain plasticity and behavior. Most previous works that cover topics related to brain plasticity do not include extensive discussions of behavior. The first to try to address the relationship between recovery from brain damage and changes in the brain that might support the recovery, this volume includes studies of humans as well as laboratory species, particularly rats. The subject matter identifies a consistent correlation between specific changes in the brain and behavioral recovery, as well as various factors such as sex and experience that influence this correlation in consistent ways. Evolving from a series of lectures given as the McEachran Lectures at the University of Alberta, this volume originally began as a summary of the lectures, but has expanded to include more background literature, allowing the reader to see the author's biases, assumptions, and hunches in a broader perspective. In writing this volume, the author had two goals in mind: * to initiate senior undergraduates or graduate psychology, biology, neuroscience or other interested students to the issues and questions regarding the nature of brain plasticity, and * to provide a monograph in the form of an extended summary of the work the author and his colleagues have done on brain plasticity and recovery of function.