Principles of Molecular Pathology


Book Description

Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.




Principles & Interpretation of Laboratory Practices in Surgical Pathology


Book Description

This book is a practical guide to all laboratory procedures in surgical pathology, covering both diagnostic and research aspects. Divided into seventeen sections, topics covered include routine and special staining procedures, cytopathology and FNAC procedures, biopsies, tissue processing and much more. A complete chapter is dedicated to microtomy. Each procedure is presented in a step by step format, explaining its principles, methodology and troubleshooting. The final chapters cover quality control, telepathology and telecytology, molecular diagnostic pathology, laboratory waste management, and the function of microscopes. Key Points Practical guide to all laboratory procedures in surgical pathology Covers both diagnostic and research aspects Complete chapter dedicated to microtomy Highly illustrated with clinical images and tables




Principles of Rubin's Pathology


Book Description

Revision of: Essentials of Rubin's pathology / editors, Emanuel Rubin, MD, Howard M. Reisner, PhD. 2014. 6th ed.




Advanced Diagnostic Methods in Pathology


Book Description

Providing a comprehensive overview of all the diagnostic techniques used in modern pathology laboratories, this textbook considers both diagnostic and prognostic applications of immunopathologic, molecular biologic, flow cytometric, and image analysis methods. The basic science behind each diagnostic method is outlined, and entire chapters focus on specific diagnostic issues for each organ system. O'Leary is affiliated with the Armed Forces Institute of Pathology. Annotation copyrighted by Book News, Inc., Portland, OR




Forensic Pathology


Book Description

Forensic Pathology is a comprehensive reference that uses a case-oriented format to address, explain and guide the reader through the varied topics encountered by forensic pathologists. Developed in response to a severe void in the literature, the book addresses topics ranging from medicolegal investigation of death to death scene investigation, forensic autopsy, and artifacts of resuscitation as well as complications of medical therapy, forensic osteology, forensic odontology, forensic photography, and death certification. The book includes various types of cases, including sudden natural death, asphyxia, motor vehicle collisions, death in custody, child abuse and elder abuse, acute psychiatric and emotional deaths, and pregnancy. It contains sample descriptions of pathological lesions which serve to aid pathologists in reporting their findings to law enforcement agencies, attorneys, and others involved in investigations of sudden death. The concepts outlined in the text are beautifully illustrated by large, colorful photographs. There are also "Do and Don't" sections at the end of each chapter that provide guidance for handling the types of cases examined. This work will benefit not only experienced forensic pathologists, but also hospital pathologists who occasionally performs medicolegal autopsies; doctors in training; medical examiners; law enforcement personnel; crime scene investigators; attorneys; and fellows and students of the medical sciences. - Large, colorful photographs which beautifully illustrate the concepts outlined in the text. - Sample descriptions of pathological lesions which serve to aid pathologists in reporting their findings to law enforcement agencies, attorneys, and others involved in investigations of sudden death. - 'Do and Don't' sections at the end of each chapter which provide guidance for handling the types of cases examined within preceding sections.




Pathology: A Modern Case Study


Book Description

A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.




Silverberg's Principles and Practice of Surgical Pathology and Cytopathology 4 Volume Set with Online Access


Book Description

Silverberg's Principles and Practice of Surgical Pathology and Cytopathology is one of the most durable reference texts in pathology. Thoroughly revised and updated, this state-of-the-art new edition encompasses the entire fields of surgical pathology and cytopathology in a single source. Its practice-oriented format uniquely integrates these disciplines to present all the relevant features of a particular lesion, side by side. Over 4000 color images depict clinical features, morphological attributes, histochemical and immunohistochemical findings, and molecular characteristics of all lesions included. This edition features new highly experienced and academically accomplished editors, while chapters are written by the leading experts in the field (several new to this edition, bringing a fresh approach). Dr Steven Silverberg's practical approach to problem solving has been carefully preserved. The print book is packaged with access to a secure, electronic copy of the book, providing quick and easy access to its wealth of text and images.




Molecular Pathology


Book Description

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. - Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease - Explains the practice of "molecular medicine and the translational aspects of molecular pathology - Teaches from the perspective of "integrative systems biology - Enhanced digital version included with purchase




Pathology: The Big Picture


Book Description

Get the BIG PICTURE of Pathology - and focus on what you really need to know to score high on the course and board exam If you want a streamlined and definitive look at Pathology - one with just the right balance of information to give you the edge at exam time - turn to Pathology: The Big Picture. You'll find a succinct, user-friendly presentation especially designed to make even the most complex concept understandable in the shortest amount of study time possible. This perfect pictorial and textual overview of Pathology delivers: A “Big Picture” emphasis on what you must know verses “what's nice to know” Expert authorship by award-winning, active instructors Coverage of the full range of pathology topics - everything from cellular adaptations and injury to genetic disorders to inflammation to diseases of immunity Magnificent 4-color illustrations Numerous summary tables and figures for quick reference and rapid retention of even the most difficult topic Highlighted key concepts that underscore integral aspects of histology (key concepts are also listed in a table at the end of each chapter) USMLE-type questions, answers, and explanations to help you anticipate what you'll encounter on the exams And much more!




Essential Concepts in Molecular Pathology


Book Description

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology