Author : Raluca-Ioana Stefan
Publisher : CRC Press
Page : 316 pages
File Size : 20,2 MB
Release : 2001-08-15
Category : Medical
ISBN : 1482271087
"Covers the most recent methods and materials for the construction, validation, analysis, and design of electrochemical sensors for bioanalytical, clinical, and pharmaceutical applications--emphasizing the latest classes of enantioselective electrochemical sensors as well as electrochemical sensors for in vivo and in vitro diagnosis, for DNA assay
Author : Sensen Chen
Publisher :
Page : 218 pages
File Size : 12,62 MB
Release : 2017
Category : Biomedical engineering
ISBN :
Recently, point-of-care diagnostics has gained great attention because it can improve patient's quality of life. Electrochemical diagnostic systems are promising because of their miniaturizability and low-cost. However, fabrication of such devices requires special skills as well as expensive equipment and supplies. This thesis is based on a research project aimed at fabricating electrochemical sensors combing wax printing and inkjet printing or wax printing and hand painting. The electrochemical sensors can be used for measuring different kinds of electrochemical analytes like dopamine, uric acid by electrochemical methods like amperometry, which can show great calibration curve. The LOD of dopamine, uric acid, ascorbic acid, Nile Blue, hydrogen peroxide and ferrocene is 0.015 μM, 7.3 μM, 30 μM, 1.3 μM, 8 nM and 30 μM, respectively. Further, we can modify the electrochemical sensor by using multiwall carbon nanotube in order to improve the sensitivity of the electrochemical sensors. This modified electrochemical sensor can also be used as immunoassay by sandwich format ELISA for detecting carcinoembryonic antigen (CEA), which has been designated as a reliable biomarker for several types of cancers. We found that the CNT modified hand-painting device can detect CEA down to 0.6 ng/mL, which is three times lower than the cut-off value of diagnosis, i.e. 5 ng/mL in blood.
Author : Giuseppe Maruccio
Publisher : Woodhead Publishing
Page : 312 pages
File Size : 11,18 MB
Release : 2022-02-01
Category : Technology & Engineering
ISBN : 0128235993
Electrochemical Sensors: From Working Electrodes to Functionalization and Miniaturized Devices provides an overview of the materials, preparation and fabrication methods for biosensor applications. The book introduces the field of electrochemistry and its fundamentals, also providing a practical overview of working electrodes as key components for the implementation of sensors and assays. Features covered include the prompt transfer of electrons, favorable redox behavior, biocompatibility, and inertness in terms of electrode fouling. Special attention is dedicated to analyzing the various working materials systems for electrodes used in electrochemical cells such as gold, carbon, copper, platinum and metal oxides. This book is suitable for academics and practitioners working in the disciplines of materials science and engineering, analytical chemistry and biomedical engineering. Introduces key concepts for electrochemistry and biosensors Reviews the most common and emerging materials-based electrodes for sensor applications, including gold, carbon, platinum and metal oxides Discusses both macro and miniaturized electrodes, including their cleaning, engineering, fabrication, examples of working biosensors, and advantages and disadvantages
Author : Salvador Alegret
Publisher : Elsevier Science
Page : 1028 pages
File Size : 35,79 MB
Release : 2007-10-18
Category : Science
ISBN : 9780444530530
Electrochemical Sensor Analysis (ECSA) presents the recent advances in electrochemical (bio)sensors and their practical applications in real clinical, environment, food and industry related samples, as well as in the safety and security arena. In a single source, it covers the entire field of electrochemical (bio)sensor designs and characterizations. The 38 chapters are grouped in seven sections: 1) Potentiometric sensors, 2) Voltammetric sensors, 3) Electrochemical gas sensors 4) Enzyme-based sensors 5) Affinity biosensors 6) Thick and thin film biosensors and 7) Novel trends. Written by experts working in the diverse technological and scientific fields related to electrochemical sensors, each section provides an overview of a specific class of electrochemical sensors and their applications. This interdisciplinary text will be useful for researchers and professionals alike. Covers applications and problem solving (sensitivity, interferences) in real sample analysis Details procedures to construct and characterize electrochemical (bio)sensors
Author : Xueji Zhang
Publisher : Academic Press
Page : 625 pages
File Size : 26,76 MB
Release : 2011-04-28
Category : Science
ISBN : 008055489X
This book broadly reviews the modem techniques and significant applications of chemical sensors and biosensors. Chapters are written by experts in the field – including Professor Joseph Wang, the most cited scientist in the world and renowned expert on sensor science who is also co-editor. Each chapter provides technical details beyond the level found in typical journal articles, and explores the application of chemical sensors and biosensors to a significant problem in biomedical science, also providing a prospectus for the future.This book compiles the expert knowledge of many specialists in the construction and use of chemical sensors and biosensors including nitric oxide sensors, glucose sensors, DNA sensors, hydrogen sulfide sensors, oxygen sensors, superoxide sensors, immuno sensors, lab on chip, implatable microsensors, et al. Emphasis is laid on practical problems, ranging from chemical application to biomedical monitoring and from in vitro to in vivo, from single cell to animal to human measurement. This provides the unique opportunity of exchanging and combining the expertise of otherwise apparently unrelated disciplines of chemistry, biological engineering, and electronic engineering, medical, physiological. Provides user-oriented guidelines for the proper choice and application of new chemical sensors and biosensors Details new methodological advancements related to and correlated with the measurement of interested species in biomedical samples Contains many case studies to illustrate the range of application and importance of the chemical sensors and biosensors
Author : Dr A. Pandikumar
Publisher : Royal Society of Chemistry
Page : 466 pages
File Size : 24,42 MB
Release : 2021-05-05
Category : Science
ISBN : 1839163143
Disposable electrodes have been widely used as a sensing platform in electrical and electrochemical sensors owing to the possibility of quantitative detection using clinical biomarkers with high precision, sensitivity and reproducibility, which are necessary for accurate diagnosis of the health condition of an individual. This book focusses on the emerging disposable electrochemical sensors in the health sector and the advancement of analytical devices to monitor diabetic, cancer and cardiovascular patients using different nanomaterials. It discusses the upcoming strategies, advantages and the limitations of the existing devices using disposable electrodes. Uniquely, it covers in-depth knowledge of mechanistic features of various designs of screen-printing electrodes and the material aspects required of sensors developed for the healthcare field. It also looks at the portable devices using a variety of materials and the future directions for research in this area. Appealing to the health care industry, this book is aimed at academic and research institutes at both the graduate and postgraduate level. The contributors are leading experts in the field and they are providing guidance for the next decade of research in the field of disposable electrochemical biosensors.
Author : Fan Xia
Publisher : Springer Nature
Page : 269 pages
File Size : 20,17 MB
Release : 2023-10-02
Category : Technology & Engineering
ISBN : 9819956447
This book illustrates recent advances in developing sensitive and selective electrochemical biosensors for their whole blood application. Known to be a cutting-edge and fast-growing technology, electrochemical biosensors demonstrate their potential in laboratories, industries, and healthcare to achieve specific and direct target detection in complex media, and have become an emerging technology for guiding personalized medicine. The book first demonstrates methods and models to cover the detection of a variety of target molecules in whole blood, including ions, small molecules, nucleic acids, proteins, cells, etc. Then, it provides comments on various detection strategies employed to improve sensors' sensitivity, specificity, selectivity, and reproducibility as well as presenting the laws and principles. In addition, it summarizes achievements and challenges from recent years. Finally, it provides future perspectives and opportunities in electrochemical biosensors including point of care detection, molecular diagnostics and the integration of this sensor platform with multidisciplinary technologies, towards the ultimate goal of personalized medicine. The book integrates abundant viewpoints from multiple sciences and is helpful and valuable to a wide readership in the various fields of biochemistry, biophysics, bioengineering, and pharmaceutics.
Author : Ali A. Ensafi
Publisher : Elsevier
Page : 388 pages
File Size : 30,74 MB
Release : 2019-07-25
Category : Science
ISBN : 0128164921
Electrochemical Biosensors summarizes fundamentals and trends in electrochemical biosensing. It introduces readers to the principles of transducing biological information to measurable electrical signals to identify and quantify organic and inorganic substances in samples. The complexity of devices related to biological matrices makes this challenging, but this measurement and analysis are critically valuable in biotechnology and medicine. Electrochemical biosensors combine the sensitivity of electroanalytical methods with the inherent bioselectivity of the biological component. Some of these sensor devices have reached the commercial stage and are routinely used in clinical, environmental, industrial and agricultural applications. Describes several electrochemical methods used as detection techniques with biosensors Discusses different modifiers, including nanomaterials, for preparing suitable pathways for immobilizing biomaterials at the sensor Explains various types of signal monitoring, along with several recognition systems, including antibodies/antigens, DNA-based biosensors, aptamers (protein-based), and more
Author : Kinga Zór
Publisher :
Page : 71 pages
File Size : 49,22 MB
Release : 2011
Category :
ISBN : 9789189627758
Author : Seyed Morteza Naghib
Publisher : Bentham Science Publishers
Page : 187 pages
File Size : 39,96 MB
Release : 2023-04-17
Category : Technology & Engineering
ISBN : 9815123947
A biosensor is an integrated receptor-transducer device that converts a biological response into an electrical signal. The design and development of biosensors have taken center stage for researchers or scientists in the recent decade owing to the wide range of biosensor applications in healthcare and disease diagnosis, environmental monitoring, water and food quality, and drug delivery. Due to their adaptability, ease of use in relatively complex samples, and portability, the significance of electrochemical biosensors in analytical chemistry has increased manifold. Electrochemistry has been pivotal in developing transduction methods for biological processes and biosensors. In parallel, the explosion of activity in nanoscience and nanotechnology and their huge success have profoundly affected biosensor technology, opening new avenues of research for electrode materials and transduction. Electrochemical Biosensors in Practice: Material and Methods particularly explores the use of silver and gold nanoparticles for signal amplification, photocurrent transduction, and aptamer design. Therefore, the book serves as an introductory text for those specializing in biosensors and bioelectronics and their practical applications. Key features Includes structured information for easy understanding of the subject Provides an introduction to biosensors and electrochemical biosensor classification Explains fundamental concepts and practical electrochemistry techniques for research Provides notes on essential electrochemical sensor materials such as graphene, carbon nanotubes, conductive polymers, and other advanced materials Provides information about electrochemical biosensor development Informs readers about recent applications and research findings Includes references for further reading
