Apoptosis and Cancer
Author : Seamus J. Martin
Publisher : R G Landes Company
Page : 265 pages
File Size : 13,60 MB
Release : 1997
Category : Medical
ISBN : 9781570594526
Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy
Author : Christopher D. Gregory
Publisher : Springer
Page : 260 pages
File Size : 15,71 MB
Release : 2016-08-24
Category : Medical
ISBN : 3319394061
Book Description
This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.
Holland-Frei Cancer Medicine
Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
Page : 2004 pages
File Size : 15,62 MB
Release : 2017-03-10
Category : Medical
ISBN : 111900084X
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Innovative Medicine
Author : Kazuwa Nakao
Publisher : Springer
Page : 330 pages
File Size : 15,99 MB
Release : 2015-10-13
Category : Science
ISBN : 4431556516
Book Description
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Necrotic Cell Death
Author : Han-Ming Shen
Publisher : Springer Science & Business Media
Page : 402 pages
File Size : 23,85 MB
Release : 2014-03-29
Category : Science
ISBN : 1461482208
Book Description
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Programmed Cell Death in Cancer Progression and Therapy
Author : Roya Khosravi-Far
Publisher : Springer Science & Business Media
Page : 362 pages
File Size : 15,35 MB
Release : 2007-12-29
Category : Medical
ISBN : 140206554X
Book Description
Programmed cell death (PCD) plays pivotal roles in tumor progression, cancer therapeutics and resistance of tumor cells to therapy. This book examines the mechanisms involved in mediating and regulating PCD in cancer. It also provides a detailed indication of the utility of PCD in cancer therapy. The book features chapters on the current and future of RNA interference in therapeutics and Pathways involved in Stem Cell Survival and Death.
Cell Death
Author : Douglas R. Green
Publisher :
Page : 0 pages
File Size : 40,6 MB
Release : 2018
Category : Science
ISBN : 9781621822141
Book Description
A million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.
Apoptosis, Senescence and Cancer
Author : David A. Gewirtz
Publisher : Springer Science & Business Media
Page : 596 pages
File Size : 27,88 MB
Release : 2007-12-17
Category : Medical
ISBN : 1588295273
Book Description
Provides insight into established practices and research into apoptosis and senescence by examining techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics which still hold mysteries for researchers. This book concludes with established cancer therapies.
When Cells Die II
Author : Richard A. Lockshin
Publisher : Wiley-Liss
Page : 578 pages
File Size : 23,31 MB
Release : 2004
Category : Medical
ISBN :
Book Description
Offers the most thorough, cutting-edge coverage of the field of cell death since publication of the first edition. Leading international researchers present an up-to-date yet accessible survey ranging from the history of cell death science to its modern methodology. Extensively revised, this new edition features relavant discussions of: the impact of genomics and proteomics; gene therapy and pharmacogenetics; the role of mitochondria; caspase-independent and non-apoptotic cell death; and evolution of mechanisms.
Flight of the Turtle
Author : Samuel Ruder
Publisher :
Page : 0 pages
File Size : 30,85 MB
Release : 2023-04-10
Category :
ISBN :
Book Description
Flight of the Turtle is a story about the power of love and a turtle that learns to fly. Vivid color and simple words are used to paint this story told through the eyes of a fisherman who loves the beauty of the sea and loves returning home to the harbor where his faithful cats eagerly await.
