Therapeutic Dressings and Wound Healing Applications


Book Description

The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.




Wound Healing


Book Description

Skin wounds are common occurrences that result from the breakdown of anatomical continuity and integrity of the epidermis, with consequent functional changes. Wound healing is a complex phenomenon through which there is healing of the skin. The wound healing process begins immediately after the wound occurs and can be a lengthy and complex process depending on the severity of the wound and the normal or abnormal healing progress. Wound healing progress through three distinct phases of inflammation, proliferation, and remodeling in a methodical and complex sequence that involves cellular, molecular, and humoral mechanisms of action. Any change in this sequence of events can lead to abnormal wound healing. Due to the health and psychological consequences of wounds that are difficult to heal there has been a continuous effort to develop new therapies that promote wound healing more quickly and effectively and that restore the skin’s barrier function. Nevertheless, this situation remains a medical challenge. This book presents some therapeutic advances based on new and innovative therapeutic options, medical devices, and biomaterials to promote wound healing. It is a theoretical and practical reference for future research on chronic wound healing.




Wound Healing and Wound Management


Book Description

Whenever the integrity of the skin is impaired, via trauma or surgical incision, wounds und wound healing are the natural consequences. Thus, every physician should be interested in the biological processes involved in wound healing. The physician does not usually interfere with these natural processes, knowing that the body heals itself (natura sanat). It is not until the natural wound healing process is disturbed, that we realize how little we know about this area. Our limited knowledge is not even available to most physicians. Advances in the areas of cell-and molecular biology have also resulted in substantial progress in the field of wound healing. Today, we know that the process of tissue repair occurs in three phases and is controlled by specific cells. These cells release potent mediators which in turn regulate the function of other cells surrounding the area. "Certain rules apply to the healing of wounds and injured tissue. You must follow nature for nature will never follow you", this sentence writen by Paracelsus in his book "Chirurgia magna" is still valid today. Current reseach in wound healing is exploring these rules and integrating them into new therapeutical concepts. The purpose of this book is to make current knowledge on basic healing processes, research in this area and on wound management available to most physicians. Due to the importance of wound healing and the successful combination of basic science and clinical aspects, I would like this book to be widely accepted.




Growth Factors and Wound Healing


Book Description

The aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repair. Written and edited by eminent experts in the field, the papers cover the general concepts of wound healing; the role of nutrients; endogenous growth factors; clinical applications of growth hormone and IGF-1 therapy; and clinical applications of peptide growth factors.




Advances in Wound Healing Materials


Book Description

Wound healing and wound care technologies are an ever expanding field with the advancement of materials science, biomedicine and tissue engineering. In the year 2011 the global wound care market generated US$ 6,500 million with an annual growth rate of 7.5%. The global advanced wound care products market share in 2023 is predicted to be approximately US$ 16,300 million.This book discusses the evolution of wound care devices and protocol over the years and different technologies being used in the present day wound care treatment. New strategies involving engineered tissues and drug delivery to mimic the natural wound healing milieu are discussed. The use of cytokine growth factors enhances chronic wound healing particularly for burn wound healing. Prevention of scarring, keloid formation or contractures and a cosmetically acceptable healing is a challenge even now.Skin tissue engineering was the first successfully clinically applied product in regenerative medicine. Bioengineered skin seeded with fibroblast and keratinocyte cells could form a permanent solution that do not require skin grafting or as a temporary cover for burns prior to grafting. Cell attachment, proliferation and tissue formation in a three-dimensional porous scaffold can be engineered for specific application. These cell based skin substitutes had significant wound healing and scar reducing effect on patients.Gene-activated dermal equivalent is another emerging approach for the healing of full thickness incision wounds with good remodelling of the skin. The book also describes similar latest developments on wound healing science and research.The target audiences are wound care professionals, researchers working on wound healing technology and skin tissue engineering; as well as graduate students and industries that need to understand the aspects of wound healing and technological orientation towards successful commercialisation.




Chronic Wound Management


Book Description

This book describes how chronic wounds follow a completely different healing trajectory to acute wounds and discusses the factors associated with these poor healing trajectories. These factors include age, chronic inflammation, phenotypic changes in such cells as macrophages, fibroblasts, and keratinocytes, colder, alkaline wound milieu, wound related hypoxemia, and diabetes. Other factors implicated include reperfusion injury, poor patient compliance, presence of undiagnosed and therefore unmanaged biofilms and wound pain. The past decades have yielded reliable evidence-based guidelines and standardized care, but the healing of diabetic foot wounds continues to be unpredictable notwithstanding these advances, while the recurrence rates are also high. The benefits of technology in wound diagnosis are evidence-based and the use of this technology also features in guidelines. However, the same argument cannot be extended to adjuvant devices to facilitate wound closure even though many devices potentially benefit wound healing. Chronic Wound Management describes how innovation is based on technology that itself informs evidence, the gap between the evidence available, the performance of technology and how do we bridge this gap. It reviews the lessons learnt from the COVID-19 pandemic and whether traditional medicine systems offer us real or imaginary benefits. Consequently, this book is an important addition to the literature in the area and an essential read for all healthcare professionals working with these patients.




Chronic Wounds, Wound Dressings and Wound Healing


Book Description

This book addresses wound care in vascular surgery, neurosurgery and lower extremity ulcers, while also providing detailed information on the latest concepts in antimicrobial therapy. The book presents essential content on the assessment, care, measurement and repair of wounds, and describes important scientific aspects as well as current clinical techniques. Due to the various topics covered, the book offers a valuable resource not only for plastic surgeons, but also for neurosurgeons, vascular surgeons and all clinicians who are interested in learning about current antimicrobial agents and their use.




Wound Healing, Tissue Repair, and Regeneration in Diabetes


Book Description

Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions. This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals. Explains diabetic wounds and their complications Assesses the role of nutraceuticals, herbal supplements and other modalities for use in treating diabetic wounds Provides protocols for diabetic wound management




Wound Healing


Book Description

This most complete resource is back in a full-color, thoroughly revised, updated, and significantly expanded 4th Edition that incorporates all of the many scientific and technological advances that are changing the scope of practice in this multidisciplinary field. Learned authors Joseph McCulloch and Luther Kloth have gathered world renown experts in wound management to present a comprehensive text that is evidence based, clinically focused and practical. Responding to the ever-changing field of wound management, the 4th Edition is far from a simple update; it is virtually a brand-new text. The committed and respected teams of authors and contributors have broadened the scope of this text and expanded it from 14 to 35 chapters.