The Laboratory Zebrafish


Book Description

Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management. In the relatively brief span




The Fish Immune System: Organism, Pathogen, and Environment


Book Description

This book comprehensively reviews the immunology of fish--their health, interactions between them and their pathogens, and the impact of both endogenous and environmental changes on these interactions. Leading authorities provide an essential foundation for the understanding of fish immunology and fish health.As fish are increasingly used as model systems for vertebrate immune systems, The Fish Immune System will be a crucial reference. - The only comprehensive, single-volume reference on the fish immune system - Contributions from an international team of experts - Useful to researchers interested in fish health as well as professionals managing fish hatcheries, aquariums, and other facilities that must maintain healthy fish




Microsporidia


Book Description

Microsporidia: Pathogens of Opportunity provides a systematic overview of the biology of microsporidia. Written by leading experts in the field, the book combines background and basic information on microsporidia with descriptive methods and resources for working with the pathogen. Newly revised and updated for its second edition, Microsporidia will continue to be the standard text reference for these pathogenic protists, and is an indispensable research resource for biologists, physicians and parasitologists. This new edition of this publication provides systematic reviews of the biology of this pathogen by leading experts in the field, and will be combined with descriptions of the methods and resources for working with this pathogen. • Provides a comprehensive summary of literature on microsporidia and microsporidiosis • The long-awaited update to the standard microsporidia reference text The Microsporidia and Microsporidiosis • Written by an international team of authors representing each of the main research groups working on microsporidia • Chapters provide comprehensive overviews of general methodology as well as special techniques related to these organisms







Management of Animal Care and Use Programs in Research, Education, and Testing


Book Description

AAP Prose Award Finalist 2018/19 Management of Animal Care and Use Programs in Research, Education, and Testing, Second Edition is the extensively expanded revision of the popular Management of Laboratory Animal Care and Use Programs book published earlier this century. Following in the footsteps of the first edition, this revision serves as a first line management resource, providing for strong advocacy for advancing quality animal welfare and science worldwide, and continues as a valuable seminal reference for those engaged in all types of programs involving animal care and use. The new edition has more than doubled the number of chapters in the original volume to present a more comprehensive overview of the current breadth and depth of the field with applicability to an international audience. Readers are provided with the latest information and resource and reference material from authors who are noted experts in their field. The book: - Emphasizes the importance of developing a collaborative culture of care within an animal care and use program and provides information about how behavioral management through animal training can play an integral role in a veterinary health program - Provides a new section on Environment and Housing, containing chapters that focus on management considerations of housing and enrichment delineated by species - Expands coverage of regulatory oversight and compliance, assessment, and assurance issues and processes, including a greater discussion of globalization and harmonizing cultural and regulatory issues - Includes more in-depth treatment throughout the book of critical topics in program management, physical plant, animal health, and husbandry. Biomedical research using animals requires administrators and managers who are knowledgeable and highly skilled. They must adapt to the complexity of rapidly-changing technologies, balance research goals with a thorough understanding of regulatory requirements and guidelines, and know how to work with a multi-generational, multi-cultural workforce. This book is the ideal resource for these professionals. It also serves as an indispensable resource text for certification exams and credentialing boards for a multitude of professional societies Co-publishers on the second edition are: ACLAM (American College of Laboratory Animal Medicine); ECLAM (European College of Laboratory Animal Medicine); IACLAM (International Colleges of Laboratory Animal Medicine); JCLAM (Japanese College of Laboratory Animal Medicine); KCLAM (Korean College of Laboratory Animal Medicine); CALAS (Canadian Association of Laboratory Animal Medicine); LAMA (Laboratory Animal Management Association); and IAT (Institute of Animal Technology).




The Zebrafish in Biomedical Research


Book Description

The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. - Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications - Includes the work of world-renowned authors - Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series




Zebrafish Protocols for Neurobehavioral Research


Book Description

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.




Host Manipulation by Parasites


Book Description

Parasites that manipulate the behaviour of their hosts represent striking examples of adaptation by natural selection. This field of study is now moving beyond its descriptive phase and into more exciting areas where the processes and patterns of such dramatic adaptations can be better understood. This innovative text provides an up-to-date, authoritative, and challenging review of host manipulation by parasites that assesses the current state of developments in the field and lays out a framework for future research. It also promotes a greater integration of behavioral ecology with studies of host manipulation (behavioral ecology has tended to concentrate mainly on behaviour expressed by free living organisms and is far less focused on the role of parasites in shaping behaviour). To help achieve this, the editors adopt a novel approach of having a prominent expert on behavioral ecology (but who does not work directly on parasites) to provide an afterword to each chapter.




The Zebrafish


Book Description

The zebrafish (Danio rerio) is a valuable and common model for researchers working in the fields of genetics, oncology and developmental sciences. This full-color atlas will aid experimental design and interpretation in these areas by providing a fundamental understanding of zebrafish anatomy. Over 150 photomicrographs are included and can be used for direct comparison with histological slides, allowing quick and accurate identification of the anatomic structures of interest. Hematoxylin and eosin stained longitudinal and transverse sections demonstrate gross anatomic relationships and illustrate the microscopic anatomy of major organs. Unlike much of the current literature, this book is focused exclusively on the zebrafish, eliminating the need for researchers to exclude structures that are only found in other fish.