Psoralen Dna Photobiology


Book Description

In one form or another psoralens have been in use dating back to biblical times for the treatment of depigmented patches of skin. However, it has only been in the past 40 years that the structure and function of psoralens have been elucidated. Although several volumes have been published on photobiology and photomedicine, no one volume has ever been devoted to the psoralen photobiology. In these two volumes we focus on the properties and uses of photoactivated psoralens.In these volumes the various aspects of psoralens are presented in a review of the field as it stands in mid 1986. In retrospect, we may find that this particular time was crucial in the development of new therapeutic modalities as many of the applications of modem molecular biology are beginning to impact on the practice of medicine.This book was written with two purposes in mind. First, to serve as an update (the last collective review of the field was in 1982). Second, it is hoped that newcomers to the fields of photobiology andphotomedicine both scientists and clinicians would find it a useful introduction.




Photobiology


Book Description

It is not always the case that the subject of a scientific book and its relevance to everyday li fe are so timely. Photobiology and its si ster subject Radiobiology are now a must for understanding the environment we live in and the impact light, ultraviolet light, and radiation have on all aspects of our life. Photobiology is a true interdisciplinary field. Photobiology research plays a direct role in diverse fields, and a glance at the topics of the symposia covered in this book by over 100 articles shows the breadth and depth of knowledge acquired in fundamental research and its impact on the major issues and applied problems the world is facing. Half a century of photobiology research brought about an understanding of the importance of light to life, both as a necessary source of energy and growth as weIl as its possible dangers. Research in photochemistry and photobiology led to the discoveries of ceIlular repair mechanisms of UV induced damages to DNA and this led to understanding of the effects of hazardous environmental chemieals and mutagenecity , and to the development of genetic engineering. This topic was given due emphasis in several symposia and chapters in this book.







Photobiology in Medicine


Book Description

Man has recognised an association of light with life and medicine for over 3000 years. Today the major challenges to this topic include the elucidation of photochemical reactions involved in photobiology at the molecular level. This includes the use of a variety of modem probing techniques that directly measures the reactivity of excited states and free radicals involved in biological reactions. This text-book is based on such an approach and has arisen from some of the lectures delivered at the NATO ASI held at Hotel Capo Caccia near the Centre for Advanced Research in Photobiology (CARP) in Sardegia, Italy. The ASI took place from 30 September -13 October 1993 and involved a total membership of 90. The book, like the NATO ASI itself, is divided into four themes starting with fundamental aspects and ending with complex medically related systems. Thus Theme 1 covers aspects of the underlying photophysics and photochemistry with particular emphasis on modem experimental techniques to study molecular mechanisms of biological processes. Theme 2 applies many of these fundamental studies to the chemical reactions of most relevance to photobiology and photomedicine such as photo-addition, -isomerization, -sensitization and -pigmentation. The third and fourth Themes deal with the deleterious and therapeutic aspects of light with particular emphasis on the use of Photo-Dynamic Therapy (PDT) to treat cancer and on viral and micro bioi infections.







Research in Photobiology


Book Description

Every four years the photobio1ogists of the world get together in an International Congress. They discuss and learn not only re search details and findings in their own, often narrow, fields but educate one another broadly in the many biological systems that interact with light. It is this latter purpose that is exemplified by these proceedings - the Symposium papers and Workshop summaries of the VIIth International Congress on Photobiology held in Rome, August 29 - September 3, 1976. Photobiology is one of the few true interdisciplinary fields. It has an air of excitement about it. A glance at the table of contents indicates clearly that photobiology and its practitioners (individuals whose primary interests are in medicine, plant sci ences, animal sciences, molecular properties, and energy conversion) interact with the entire and diverse world of living creatures. We supply not only the basic research background to help evaluate many present-day environmental problems but are also evaluating and pointing the way toward solutions to a number of these problems.




Lasers in Photomedicine and Photobiology


Book Description

This Conference on biomedical applications of. lasers ~Ias organized by the Quantum Electronics Divisional Board of the European Physical Society (E.P.S.) and held at the Villa of Poggio Imperiale in Florence, September 3-6, 1979. As kno~m, laser surgery (especially microsurgery and endoscopic photo coagulation) has recently made important progress, and the field is expand i ng rapidly. Very significant applications of lasers have also been achieved in Bi ology during recent years (cell microsurgery, cell counting and sorting, cytofluorimeter devices, etc.) and the potential of laser techniques in this field is nO~1 sufficiently well establ ished. A new class of applications of laserradiJtion in Medicine has recently been made possible by important results obtained with low intensity (non coagulative) visible lasers, such as photodynamic therapy of tumors. At the same time important branches of Medicine, where light effects are studied and optical techniques are presently used for a certain number of clinical applications, such as dermatology and pediatry, appear to be still in their infancy as far as the proper use of optical radiation and techniques, and the understanding of fundamental photoinduced biological processes are con cerned. Moreover, laser photobiology appears a very promising field for the investigation of fundamental processes at the biomolecular level.




CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2


Book Description

The second edition of this best-selling handbook is bigger, more comprehensive, and now completely current. In addition to thorough updates to the discussions featured in the first edition, this edition includes 66 new chapters that reflect recent developments, new applications, and emerging areas of interest. Within the handbook's 145 critically r




Photoimmunology


Book Description

The skin immune response/photoallergy/photoimmunology of lupus/UV & infectious disease/therapeutic photoimmunology.