Pulmonary Involvement in Patients with Hematological Malignancies


Book Description

The number of patients treated for hematological malignancies is increasing steadily. To maximize cure rates, aggressive treatments have been introduced, including high-dose chemotherapy, stem cell transplantation, and targeted therapies. As a result, overall and disease-free survival rates have improved substantially, but at the price of life-threatening toxic and infectious complications that chiefly target the lung. This book provides clinicians caring for patients with hematological malignancies with detailed, up-to-date information on all relevant aspects of pulmonary involvement. Individual sections are devoted to epidemiology, diagnostic strategy, lung infections, non-infectious pulmonary involvement, and treatment, including decision making in patients with acute respiratory failure. Each of these sections contains a number of chapters, all written by leading international experts. In addition, the reader’s attention is drawn to important "pearls" relating to each condition.




Pulmonary Complications of Non-Pulmonary Malignancy, An Issue of Clinics in Chest Medicine, E-Book


Book Description

This issue of Clinics in Chest Medicine focuses on Pulmonary Complications of Non-Pulmonary Malignancy. Editors Guang-Shing Cheng and Jennifer Possick have assembled an expert team of authors on topics such as: Pulmonary manifestations of non-pulmonary solid malgnancies; Pulmonary manifestations of leukemia and lymphoma; Radiation pneumonitis; Toxicities from conventional chemotherapy; Toxicities from novel targeted therapies; Bacterial pneumonia; Fungal pneumonia; Viral pneumonia; IPS and other early onset non-infectious pulmonary syndromes; Pulmonary GVHD and other late-onset non-infectious pulmonary syndromes; Pulmonary function and pre-transplant risk assessment; Diagnostic Evaluation of Pulmonary Abnormalities in Hematologic Malignancy and HCT; Acute respiratory failure in patients with non-pulmonary malignancy; Critical care prognosis and outcomes in patients with non-pulmonary malignancy; and Palliative and end-of-life care.




Infections in Hematology


Book Description

Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and in particular, the intensive myelosuppressive chemo and immunotherapy. This textbook provides a clinically oriented, compact and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified and further aspects of the microbiological background are explored. Clinical, imaging, and laboratory-based diagnostic techniques are discussed and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization and the use of hematopoietic growth factors.




Childhood Cancer and Functional Impacts Across the Care Continuum


Book Description

Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.




Oncologic Critical Care


Book Description

This major reference work is the most comprehensive resource on oncologic critical care. The text reviews all significant aspects of oncologic ICU practices, with a particular focus on challenges encountered in the diagnosis and management of the critically ill cancer patient population. Comprised of over 140 chapters, the text explores such topics as the organization and management of an oncologic ICU, diseases and complications encountered in the oncologic ICU, multidisciplinary care, surgical care, transfusion medicine, special patient populations, critical care procedures, ethics, pain management, and palliative care. Written by worldwide experts in the field, Oncologic Critical Care is a valuable resource for intensivists, advance practice providers, nurses, and other healthcare providers, that will help close significant knowledge and educational gaps within the realm of medical care for critically ill cancer patients.




Radiological Imaging in Hematological Malignancies


Book Description

One of the first book’s to deal specifically with imaging of the entire spectrum of hematological malignancies. The use of the latest imaging modalities is well described, and an important aspect of the book is the role of imaging techniques in differentiating between manifestations of the underlying disease and complications of treatment. Each of the 28 chapters is written by an internationally recognized expert, making this book the most current and complete treatment of this subject available. Includes many high-quality radiological and histological illustrations. It should be of great interest to radiologists and hematologists.




Managing Infections in Patients With Hematological Malignancies


Book Description

Managing infections that complicate care of neutropenic patients with leukemia and hematopoietic stem cell recipients has become a distinct specialty. In Managing Infections in Patients with Hematological Malignancies, the authors and editor draw on their extensive expertise while providing a roadmap for hematologists to efficiently manage the complex infections within their patients. The first section of the text reviews viral, bacterial, and fungal pathogens, and provides brief descriptions of the microbes and diseases they cause in patients with hematological malignancies. The second section is devoted to management of infections in patients with the different underlying hematological malignancies, while the third addresses several important topics that are often ignored in most books about infections and hematological malignancies. Managing Infections in Hematological Malignancies is a useful tool for all clinicians and practicing hematologists who treat individual patients and aspire to build stronger infectious diseases programs within their respective cancer centers.




Cancer-Associated Thrombosis


Book Description

Showcasing the expertise of top-tier specialists who contributed to the newly released guidelines for the care of thrombosis in cancer patients, this exciting guide was written and edited by members of the American Society of Clinical Oncology panel, (ASCO), on the prevention and treatment of cancer-associated thrombosis, among others, and provides




Textbook of Pulmonary and Critical Care Medicine


Book Description

The second edition of the comprehensive two volume set brings respiratory medicine specialists fully up to date with the latest advances and information in their field. Beginning with an introduction to lung development and physiology of the respiratory system, the next chapters discuss pharmacology, symptoms, and respiratory diagnosis. Each of the following sections is dedicated to a specific type of respiratory disease or infection, further divided to provide in depth detail on every aspect of the topic. The text also explains how each respiratory disorder may be associated with other medical specialities such as critical care, cardiology, sleep medicine, and infectious diseases. This two volume set features numerous pulmonary radiographs including CT, nuclear images, bronchoscopy, and thoracoscopy, as well as tables and diagrams to enhance learning. Key Points Fully updated, new edition of two volume set providing latest advances in pulmonary and critical care medicine Covers numerous respiratory diseases and infections and their comorbidity with other medical specialties Highly illustrated with radiographic images, tables and diagrams Previous edition (9789350250730) published in 2011




Acute Pulmonary Embolism


Book Description

The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.