Pyrogens
Author : Frederick C. Pearson
Publisher :
Page : 296 pages
File Size : 22,7 MB
Release : 1985
Category : Medical
ISBN :
Author : Frederick C. Pearson
Publisher :
Page : 296 pages
File Size : 22,7 MB
Release : 1985
Category : Medical
ISBN :
Author : G. E. W. Wolstenholme
Publisher : John Wiley & Sons
Page : 248 pages
File Size : 30,31 MB
Release : 2009-09-16
Category : Medical
ISBN : 0470717459
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Author : Jean-Marc Cavaillon
Publisher : John Wiley & Sons
Page : 1818 pages
File Size : 34,16 MB
Release : 2018-02-20
Category : Medical
ISBN : 3527338993
Dieses Fachbuch erläutert die molekularen Grundlagen von Entzündungen, spannt den Bogen zu Infektionskrankheiten und den Zusammenhang zwischen Entzündungen und chronischen Erkrankungen, behandelt abschließend den Heilungsprozess und zeigt Therapiemöglichkeiten.
Author : Michael J. Akers
Publisher : CRC Press
Page : 517 pages
File Size : 17,32 MB
Release : 2016-04-19
Category : Medical
ISBN : 1420020560
Sterile Drug Products: Formulation, Packaging, Manufacturing, and Quality teaches the basic principles of the development and manufacture of high quality sterile dosage forms. The author has 38 years of experience in the development and manufacture of sterile dosage forms including solutions, suspensions, ophthalmics and freeze dried products. This
Author : Joseph E. Alouf
Publisher : Elsevier
Page : 1072 pages
File Size : 43,18 MB
Release : 2005-12-20
Category : Science
ISBN : 0080456987
This book describes the major achievements and discoveries relevant to bacterial protein toxins since the turn of the new century illustrated by the discovery of more than fifty novel toxins (many of them identified through genome screening). The establishment of the three-dimensional crystal structure of more than 20 toxins during the same period offers deeper knowledge of structure-activity relationships and provides a framework to understand how toxins recognize receptors, penetrate membranes and interact with and modify intracellular substrates. Edited by two of the most highly regarded experts in the field from the Institut Pasteur, France 14 brand new chapters dedicated to coverage of historical and general aspects of toxinology Includes the major toxins of both basic and clinical interest are described in depth Details applied aspects of toxins such as therapy, vaccinology, and toolkits in cell biology Evolutionary and functional aspects of bacterial toxins evaluated and summarized Toxin applications in cell biology presented Therapy (cancer therapy, dystonias) discussed Vaccines (native and genetically engineered vaccines) featured Toxins discussed as biological weapons, comprising chapters on anthrax, diphtheria, ricin etc.
Author : Baxter Laboratories, inc
Publisher :
Page : 377 pages
File Size : 21,84 MB
Release : 1952
Category : Fever
ISBN :
Author : Kevin L. Williams
Publisher : Springer
Page : 869 pages
File Size : 35,9 MB
Release : 2019-07-24
Category : Medical
ISBN : 3030171485
Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects. The intersection of test activities includes the use of an ancient blood system from an odd “living fossil” (Limulus). It is used to detect remnants of the most primitive and destructive forms of life (prokaryotes) as contaminants of complex modern systems (mammalian and Pharma). Recent challenges in the field include those associated with the application of traditional methods to new types of molecules and manufacturing processes. The advent of “at will” production of biologics in lieu of harvesting animal proteins has revolutionized the treatment of disease. While the fruits of the biotechnology revolution are widely acknowledged, the realization of the differences in the means of production and changes in the manner of control of potential impurities and contaminants in regard to the new versus the old are less widely appreciated. Endotoxin as an ancient, dynamic interface between lifeforms, provides a singular perspective from which to view the parallel development of ancient and modern organisms as well as the progress of man in deciphering the complexity of their interactions in his efforts to overcome disease.
Author : Dr. Marina Koland
Publisher : I K International Pvt Ltd
Page : 490 pages
File Size : 38,52 MB
Release : 2023-05-15
Category : Medical
ISBN : 9390620651
Industrial Pharmacy is the science of manufacturing, development, marketing and distribution of drug products, including quality assurance of the developed drug formulation. This book covers all topics required by students of Pharmacy. Industrial Pharmacy: A textbook is divided into two parts, ‘Industrial Pharmacy’ Part-I explains the formulation, manufacture, and quality control of tablets, capsules, parenteral dosage forms, liquid orals, ophthalmic dosage form and aerosols. In addition, topics such as ‘Pre-formulation’, ‘Cosmetics’ and ‘Packaging Material Science’ have also been briefly discussed. Part-II has been designed with the objective of imparting knowledge of the pilot plant scaleup considerations of different dosage forms. The students will be able to understand the technology transfer process from R&D to production with the necessary documentation. This book also provides information about drug regulations, roles and responsibilities of drug regulatory requirements such as ANDA and NDA, QMS.
Author : Baldev Prajapati
Publisher : Jaypee Brothers Medical Publishers
Page : 307 pages
File Size : 18,92 MB
Release : 2023-03-10
Category : Medical
ISBN : 9356960380
This book is a compendium of signs and symptoms that paediatricians may encounter in everyday clinical practice. Divided into 102 signs and symptoms, each one is presented in a step by step approach, with a brief introduction, a clear description of the indication, its prevalence in practice, history taking guidance, analysis tips and probable aetiology. Causes of each sign and symptom are listed sequentially from most common, to less common, and rare. The comprehensive text is highly illustrated with tables and clinical photographs to assist learning. This invaluable manual serves as a practical, ready reckoner for quick and accurate diagnosis, for practising and trainee paediatricians.
Author : Tim Sandle
Publisher : Elsevier
Page : 370 pages
File Size : 44,20 MB
Release : 2013-10-31
Category : Medical
ISBN : 1908818638
Failure to adequately control any microbial challenge associated within process or product by robust sterilisation will result in a contaminated marketed product, with potential harm to the patient. Sterilisation is therefore of great importance to healthcare and the manufacturers of medical devices and pharmaceuticals. Sterility, sterilisation and sterility assurance for pharmaceuticals examines different means of rendering a product sterile by providing an overview of sterilisation methods including heat, radiation and filtration. The book outlines and discusses sterilisation technology and the biopharmaceutical manufacturing process, including aseptic filling, as well as aspects of the design of containers and packaging, as well as addressing the cleanroom environments in which products are prepared. Consisting of 18 chapters, the book comprehensively covers sterility, sterilisation and microorganisms; pyrogenicity and bacterial endotoxins; regulatory requirements and good manufacturing practices; and gamma radiation. Later chapters discuss e-beam; dry heat sterilisation; steam sterilisation; sterilisation by gas; vapour sterilisation; and sterile filtration, before final chapters analyse depyrogenation; cleanrooms; aseptic processing; media simulation; biological indicators; sterility testing; auditing; and new sterilisation techniques. Covers the main sterilisation methods of physical removal, physical alteration and inactivation Includes discussion of medical devices, aseptically filled products and terminally sterilised products Describes bacterial, pyrogenic, and endotoxin risks to devices and products