Radiotherapy of Intraocular and Orbital Tumors


Book Description

Since the publication of the first edition of Radiotherapy of Intraocular and Orbital Tumors in 1993 the treatment programs for cure have changed from the dominance of surgical resection to the utilization of radiation therapy with preservation of the eye intact and preservation of vision. In 2002 about 2,300 primary eye tumors will be diagnosed in the United states, 75% of which will be choroidal melanomas, 20% retinoblastomas, and the remainder a wide variety of tumors - malignant lymphoma, rhabdomyosarcomas, liposarcomas, meningiomas, malignant fibrous histiocytomas, etc. Even so, the majority of malignant tumors of the eye are metastatic, primarily from cancers of the lung or breast. The impact of newer imaging studies, including computed tomography, magnetic resonance imaging, and ultrasound with and without contrast medium, have allowed for better tumor definition, more precise treatment techniques, and major improvement in local control, with preservation of the eye intact and excellent survival. The better histologic definition of the tumor has selected more appropriately the cases suitable for adjuvant chemotherapy particularly demonstrated by the combined integrated multimodal treatment of rhabdomyosarcoma without enucleation. Surgical techniques are now being reserved for biopsy and for treatment failures, a dramatic change in treatment approaches since 1993. The second edition by Sagerman and Alberti clearly demonstrates this major change in treatment. The volume explores the impact of diagnostic workup, the role of surgery, the role of external beam radiation therapy, the use of radioactive plaques, photocoagulation, cryotherapy, and other less major surgical procedures.




Surgical Ophthalmic Oncology


Book Description

Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this Open Access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is an ideal reference for general ophthalmologists, surgeons, fellows and trainees around the world who encounter these diseases in the care of their patients. Notably, this book includes considerations for those ophthalmologists offering subspecialty care in environments with limited access to advanced technology and instrumentation. Individual chapters address diagnostic indications, pre-operative and post-operative concerns, and provide detailed explanations of surgical techniques required to manage various eye cancer ailments with help of ample illustrations. High-quality videos included throughout the book provide readers with the opportunity to review surgical steps in real-time as a learning tool. Chapters thoroughly cover tumors of eyelid, cornea and conjunctiva, orbit as well as intraocular tumors, while later chapters discuss ophthalmic radiation therapy. The book concludes with a section on ophthalmic pathology which details essential guidelines on relevant aspects from specimen collection and transport, to interpretation of the pathology report. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is a unique and necessary valuable resource for ophthalmologists, trainees, and related medical professionals working in underserved areas in providing quality care for patients suffering from ocular cancers.




Orbital Tumors


Book Description

Orbital Tumors, 2nd edition discusses advances in orbital disease and their treatment, offering readers an up-to-date, single volume reference for orbital tumors. Divided into two parts, this book covers everything from advances in oncogenesis and its relationship to orbital tumors, to medical genetics and the role of imaging in diagnosis of orbital tumors. Additionally, new information on incidence and behavior of tumors resulting from environmental and social trends is included. Written and edited by leaders in the fields of ophthalmology and oncology, Orbital Tumors, 2nd edition builds upon the first edition, proving to be a useful reference for orbital specialists and of significant interest for everyone dealing with orbital pathology from a clinical and scientific point of view.




Encyclopedia of Radiation Oncology


Book Description

This comprehensive encyclopedia, comprising a wide range of entries written by leading experts, provides detailed information on radiation oncology, including the most recent developments in the field. It will be of particular value for basic and clinical scientists in academia, practice, and industry and will also be of benefit to those in related fields, students, teachers, and interested laypersons.




Radiotherapy of Intraocular and Orbital Tumors


Book Description

Radiotherapy of Intraocular and Orbital Tumors presents a new approach to the role of radiation therapy in the management of ophthalmic cancer. The indications for ultrasonography, computed tomography, and magnetic resonance imaging studies are analyzed, and treatment techniques, together with their results, are described for each tumor. Particle beam and plaque irradiation are reviewed, and conservative and surgical management of radiation effects are detailed. In the past, most books on this subject included a chapter on radiotherapy but emphasized the dangers of radiation complications. However, great progress in understanding the effects of irradiation upon the tissues of the eye and orbit, new therapeutic equipment, and new imaging techniques (CT, MRI) allow for careful treatment planning. This book has taken the long overdue step of reconsidering the role of irradiation of the eye so that it may take its place as a respected, rather than feared, treatment in the combined modality approach so important today. Together with experts in relevant fields, the editors have produced a refreshingly clear and thoroughly referenced volume which will be a valuable asset to all ophthalmologists, radiation oncologists, pediatricians, endocrinologists, oncologists, and residents in training, as well as to students in these disciplines.




Clinical Ophthalmic Oncology


Book Description

Written by internationally renowned experts, Clinical Ophthalmic Oncology provides practical guidance and advice on the diagnosis and management of the complete range of ocular cancers. The book supplies all of the state-of-the-art knowledge required in order to identify these cancers early and to treat them as effectively as possible. Using the information provided, readers will be able to provide effective patient care using the latest knowledge on all aspects of ophthalmic oncology, to verify diagnostic conclusions based on comparison with numerous full-color clinical photographs, and to locate required information quickly owing to the clinically focused and user-friendly format. In this volume, all aspects of the diagnosis, histopathology, genetics and treatment of retinoblastoma are discussed in detail.




Transpupillary Thermotherapy


Book Description




Carbon-Ion Radiotherapy


Book Description

This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.




Holland-Frei Cancer Medicine


Book Description

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates




Ophthalmic Oncology


Book Description

This book highlights the unique aspects of oncologic ophthalmology as a medical and surgical discipline practiced at a comprehensive cancer center. Multi-disciplinary management of ocular, orbital and adnexal cancers are highlighted using simple and tried-and-true algorithms. In addition, ocular problems caused as a direct result of cancer treatment are reviewed using illustrative photographs and case presentations. The content is provided by full-time ophthalmology faculty and fellows at M. D. Anderson Cancer Center. Experts in complementary disciplines such as ophthalmic pathology, dermatopathology, radiation oncology, radiology, and other surgical subspecialties have brought their unique perspective to each chapter. The book is abundant with clinical photographs as well as interesting case presentations that will help the clinician correctly diagnose cancers of the orbit, eye, and adnexal structures, initiate appropriate management, as well as recognize and treat common ocular complications of cancer therapy.