Rapid Prototyping of Biomaterials


Book Description

Rapid Prototyping of Biomaterials: Principles and Applications provides a comprehensive review of established and emerging rapid prototyping technologies (such as bioprinting) for medical applications. Rapid prototyping, also known as layer manufacturing, additive manufacturing, solid freeform fabrication, or 3D printing, can be used to create complex structures and devices for medical applications from solid, powder, or liquid precursors. Following a useful introduction, which provides an overview of the field, the book explores rapid prototyping of nanoscale biomaterials, biosensors, artificial organs, and prosthetic limbs. Further chapters consider the use of rapid prototyping technologies for the processing of viable cells, scaffolds, and tissues. With its distinguished editor and international team of renowned contributors, Rapid Prototyping of Biomaterials is a useful technical resource for scientists and researchers in the biomaterials and tissue regeneration industry, as well as in academia. - Comprehensive review of established and emerging rapid prototyping technologies (such as bioprinting) for medical applications - Chapters explore rapid prototyping of nanoscale biomaterials, biosensors, artificial organs, and prosthetic limbs - Examines the use of rapid prototyping technologies for the processing of viable cells, scaffolds, and tissues




Rapid Prototyping of Biomaterials


Book Description

Rapid Prototyping of Biomaterials: Techniques in Additive Manufacturing, Second Edition, provides a comprehensive review of emerging rapid prototyping technologies, such as bioprinting, for biomedical applications. Rapid prototyping, also known as additive manufacturing, solid freeform fabrication, or 3D printing, can be used to create complex structures and devices for medical applications from solid, powder or liquid precursors. Sections explore a variety of materials, look at applications, and consider the use of rapid prototyping technologies for constructing organs. With its distinguished editor and international team of renowned contributors, this book is a useful, technical resource for scientists and researchers in academia, biomaterials and tissue regeneration. - Presents a comprehensive review of established and emerging additive manufacturing technologies (such as bioprinting) for medical applications - Contains chapters that explore the additive manufacturing of nanoscale biomaterials for a range of applications, from drug delivery, to organ printing - Includes new information on 3D printing on a variety of material classes




Essentials of 3D Biofabrication and Translation


Book Description

Essentials of 3D Biofabrication and Translation discusses the techniques that are making bioprinting a viable alternative in regenerative medicine. The book runs the gamut of topics related to the subject, including hydrogels and polymers, nanotechnology, toxicity testing, and drug screening platforms, also introducing current applications in the cardiac, skeletal, and nervous systems, and organ construction. Leaders in clinical medicine and translational science provide a global perspective of the transformative nature of this field, including the use of cells, biomaterials, and macromolecules to create basic building blocks of tissues and organs, all of which are driving the field of biofabrication to transform regenerative medicine. - Provides a new and versatile method to fabricating living tissue - Discusses future applications for 3D bioprinting technologies, including use in the cardiac, skeletal, and nervous systems, and organ construction - Describes current approaches and future challenges for translational science - Runs the gamut of topics related to the subject, from hydrogels and polymers to nanotechnology, toxicity testing, and drug screening platforms




Direct-Write Technologies for Rapid Prototyping Applications


Book Description

Direct-Write Technologies covers applications, materials, and the techniques in using direct-write technologies. This book provides an overview of the different direct write techniques currently available, as well as a comparison between the strengths and special attributes for each of the techniques. The techniques described open the door for building prototypes and testing materials. The book also provides an overview of the state-of-the-art technology involved in this field. Basic academic researchers and industrial development engineers who pattern thin film materials will want to have this text on their shelves as a resource for specific applications. Others in this or related fields will want the book to read the introductory material summarizing isuses common to all approaches, in order to compare and contrast different techniques. Everyday applications include electronic components and sensors, especially chemical and biosensors. There is a wide range of research and development problems requiring state-of-the-art direct write tools. This book will appeal to basic researchers and development engineers in university engineering departments and at industrial and national research laboratories. This text should appeal equally well in the United States, Asia, and Europe. Both basic academic researchers and industrial development engineers who pattern thin film materials will want to have this text on their shelves as a resource for specific applications. An overview of the different direct write techniques currently available A comparison between the strengths and special attributes for each of the techniques An overview of the state-of-the-art technology involved in this field




Rapid Prototyping, Rapid Tooling and Reverse Engineering


Book Description

This book introduces the role of Rapid Prototyping Techniques within the product development phase. It deals with the concept, origin, and working cycle of Rapid Prototyping Processes with emphasis on the applications. Apart from elaboration of engineering and non-engineering applications, it highlights recent applications like Bio-Medical Models for Surgical Planning, Molecular Models, Architectural Models, Sculptured Models, Psycho-Analysis Models. Special emphasis has been provided to the technique of generating human organs from live cells/tissues of the same human named 3D BIO PRINTERS. As the Rapid Prototyping Techniques are for tailor made products and not for mass manufacturing hence the book also elaborates on the mass manufacturing of rapid prototyped products. This includes casting and rapid tooling. The book concludes with Reverse Engineering and the role played by Rapid Prototyping Techniques towards the same. With globalization of market and advances in science and technology, the life span of products has shortened considerably. For early realization of products and short development period, engineers and researchers are constantly working together for more and more efficient and effective solutions. The most effective solution identified has been usage of computers in both designing and manufacturing. This gave birth to the nomenclatures CAD (Computer Aided Designing) and CAM (Computer aided Manufacturing). This was the initiation that ensured short product development and realization period. Researchers coined the concept as Rapid Prototyping. In contrast to Prototyping, Rapid prototyping is a group of techniques used to quickly fabricate a scale model of a physical part or assembly using three-dimensional computer aided design (CAD) data. Construction of the part or assembly is usually done using 3D printing or "additive or subtractive layer manufacturing" technology. The first methods for rapid prototyping became available in the late 1980s and were used to produce models and prototype parts. Today, they are used for a wide range of applications and are used to manufacture production-quality parts in relatively small numbers if desired without the typical unfavorable short-run economics. This economy has encouraged online service bureaus for early product realization or physical products for actual testing. This book is expected to contain Seven Chapters. Chapter 1 would explain product life cycle and the product development phase in the same, introducing role of Rapid Prototyping Techniques in Product development phase. Chapter 2 would deals with the concept, origin and working cycle of Rapid Prototyping Processes. Chapter 3 would concentrates on the applications of Rapid Prototyping Technology. Apart from elaboration of engineering and non-engineering applications, it also elaborates on recent applications like Bio-Medical Models for Surgical Planning, Molecular Models, Architectural Models, Sculptured Models, Psycho-Analysis Models etc. Chapter 4 would introduce the various Rapid Prototyping systems available worldwide. The chapter also introduces the technique of generating human organs from live cells/tissues of the same human named 3D BIO PRINTERS hence ensuring low rejection rate by human body. As the Rapid Prototyping Techniques are for tailor made products and not for mass manufacturing hence Chapter 5 would elaborates on the mass manufacturing of rapid prototyped products. This includes Casting and Rapid Tooling. Chapter 6 would deal with Reverse Engineering and the role played by Rapid Prototyping Techniques towards the same. As the product realization is primarily dependent on various softwares which are required to be understood for better accuracy so the concluding chapter of the book i.e. Chapter 7 would explain some software associated with the various techniques.




Biointegration of Medical Implant Materials


Book Description

Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. - Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration - Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction - Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery




3D Printing with Biomaterials


Book Description

Additive manufacturing or 3D printing, manufacturing a product layer by layer, offers large design freedom and faster product development cycles, as well as low startup cost of production, on-demand production and local production. In principle, any product could be made by additive manufacturing. Even food and living organic cells can be printed. We can create, design and manufacture what we want at the location we want. 3D printing will create a revolution in manufacturing, a real paradigm change. 3D printing holds the promise to manufacture with less waste and energy. We can print metals, ceramics, sand, synthetic materials such as plastics, food or living cells. However, the production of plastics is nowadays based on fossil fuels. And that’s where we witness a paradigm change too. The production of these synthetic materials can be based also on biomaterials with biomass as feedstock. A wealth of new and innovative products are emerging when we combine these two paradigm changes: 3D printing and biomaterials. Moreover, the combination of 3D printing with biomaterials holds the promise to realize a truly sustainable and circular economy.




Materiomics


Book Description

This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research.




3D Bioprinting in Regenerative Engineering


Book Description

Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications




Biomaterials Fabrication and Processing Handbook


Book Description

This volume focuses on a variety of production and processing aspects of the latest biomaterials. It discusses how scaffolds are used in tissue engineering and describes common implant materials, such as hard tissue, blood contacting, and soft tissue. The book also examines the important role nanotechnology plays in the preparation of drugs, protein delivery, tissue engineering, cardiovascular biomaterials, hard tissue replacements, biosensors, and bio-MEMS. With contributions from renowned international experts and extensive reference lists in each chapter, this book provides detailed, practical information to produce biomaterials and employ them in biomedicine.