Author : Lawrence J. Berliner
Publisher : Springer Nature
Page : 237 pages
File Size : 14,74 MB
Release : 2020-08-08
Category : Science
ISBN : 303047318X
This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
Author : Ulla G. Knaus
Publisher : Humana
Page : 718 pages
File Size : 12,41 MB
Release : 2019-06-07
Category : Science
ISBN : 9781493994236
This detailed volume explores the NADPH oxidase family of enzymes in human physiology and genetic disease, in which early discoveries represent prime examples of the finest translational “from bed to bench and back” studies. Methods are included for testing assembly and function of multicomponent oxidase complexes and for analyzing reactive oxygen species (ROS) generation in different systems by various means, while addressing pitfalls of ROS probes currently being used, as well as protocols on NADPH oxidase regulation and their function in cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, NADPH Oxidases: Methods and Protocols will aid researchers working with the NOX/DUOX family in continuing and expanding upon their vital research.
Author : S. Tsuyoshi Ohnishi
Publisher : CRC Press
Page : 610 pages
File Size : 20,36 MB
Release : 1995-07-27
Category : Science
ISBN : 9780849380945
Central nervous system trauma, which encompasses stroke, subarachnoid hemorrhage, head injury, and spinal cord injury, is a leading cause of death in developed countries. In the search for underlying mechanisms, membrane involvement has been the common link. This fourth volume in the Membrane-Linked Diseases series is therefore dedicated to research on CNS trauma. Focusing on the mechanism of membrane damage, Central Nervous System Trauma: Research Techniques presents a variety of experimental techniques to study the mechanism of CNS trauma. Animal and tissue culture models provide the bulk of the research findings in this area. Possible pharmacological interventions are analyzed. This volume offers numerous illustrative examples, including full color figures. This book serves as a valuable resource for students and researchers, assisting in the comprehension of current trends in CNS trauma and helping to stimulate the discovery of new research areas.
Author : Manfred Schwab
Publisher : Springer Science & Business Media
Page : 3307 pages
File Size : 25,17 MB
Release : 2008-09-23
Category : Medical
ISBN : 3540368477
This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.
Author : Manfred Lamprecht
Publisher : CRC Press
Page : 304 pages
File Size : 41,44 MB
Release : 2014-09-17
Category : Medical
ISBN : 1466567570
The use of antioxidants in sports is controversial due to existing evidence that they both support and hinder athletic performance. Antioxidants in Sport Nutrition covers antioxidant use in the athlete ́s basic nutrition and discusses the controversies surrounding the usefulness of antioxidant supplementation. The book also stresses how antioxidants may affect immunity, health, and exercise performance. The book contains scientifically based chapters explaining the basic mechanisms of exercise-induced oxidative damage. Also covered are methodological approaches to assess the effectiveness of antioxidant treatment. Biomarkers are discussed as a method to estimate the bioefficacy of dietary/supplemental antioxidants in sports. This book is useful for sport nutrition scientists, physicians, exercise physiologists, product developers, sport practitioners, coaches, top athletes, and recreational athletes. In it, they will find objective information and practical guidance.
Author : Kazuwa Nakao
Publisher : Springer
Page : 330 pages
File Size : 45,52 MB
Release : 2015-10-13
Category : Science
ISBN : 4431556516
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Author : Ronald Ross Watson
Publisher : Academic Press
Page : 801 pages
File Size : 24,93 MB
Release : 2012-10-22
Category : Technology & Engineering
ISBN : 0123977649
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohn's, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology. - Addresses the most positive results from dietary interventions using bioactive foods to impact diseases of the liver and gastrointestinal system, including reduction of inflammation, improved function, and nutritional efficiency - Presents a wide range of liver and gastrointestinal diseases and provides important information for additional research - Associated information can be used to understand other diseases, which share common etiological pathways
Author : Angel Catalá
Publisher : Nova Science Publishers
Page : 376 pages
File Size : 17,98 MB
Release : 2017
Category : Science
ISBN : 9781536105308
This book presents an overview of lipid peroxidation: inhibition, effects and mechanisms. The topics analyzed, cover a broad spectrum of functions played by lipid peroxidation and presents new information in this area of research. The topics analyzed include: progress in the knowledge of lipid peroxidation, from the first evidences issued by Nicolas Theodore de Saussure in Paris 1804; fighting against lipid peroxidation: the unique story of docosahexaenoic acid in the brain; protective effects of melatonin and structurally-related molecules in reducing membrane rigidity due to lipid peroxidation; synergistic effects of antioxidant compositions during inhibited lipid autoxidation; lipid peroxidation and animal longevity; free radicals in health and disease; lipid peroxidation in autoimmune diseases; aldehydes derived from lipid peroxidation in cancer and autoimmunity; the role of reactive oxygen species and lipid peroxidation in the neurodegenerative process after spinal cord injury; kinetics and mechanisms of inhibited lipid autoxidation in presence of 4-substituted-coumarins; hypoxia and oxidative stress: cell signaling mechanisms and protective role of vitamin C and cilnidipine; characterization of oxidative stress and antioxidant potency; paying attention to time and location; lipid peroxidation in aquatic organisms: ontogenetic, phylogenetic and ecological aspects; chemistry of lipid oxidation in edible oils; and menopause progression and oxidative stress: associated mechanisms and the importance of physical exercise.
Author : Pınar Atukeren
Publisher : BoD – Books on Demand
Page : 160 pages
File Size : 48,24 MB
Release : 2021-12-08
Category : Science
ISBN : 1839688254
Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases. This book examines lipid peroxidation as a current and future biomarker of oxidative stress.
Author : Victor R Preedy
Publisher : Academic Press
Page : 456 pages
File Size : 50,40 MB
Release : 2020-04-24
Category : Medical
ISBN : 0128157771
Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer. - Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of diabetes and oxidation issues - Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet, its food matrix or plant - Includes preclinical, clinical and population studies to help endocrinologists, diabetologists, nutritionists, dieticians and clinicians map out key areas for research and further clinical recommendations
