Neuropsychopharmacology


Book Description

Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC




Recent Advances in Neuropsycho-Pharmacology


Book Description

Recent Advances In Neuropsychopharmacology contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general practitioners. Part III examines blood platelets as a model system for central monoaminergic neurons. Part IV focuses on anxiety pathways in the brain. Part V considers prospects for a biochemical classification system in psychiatry. Part VI presents pharmacokinetic studies of psychotropic drugs. Part VI contains two papers on the renal function and renal histology of lithium patients on maintenance lithium therapy and pre-lithium patients; and the treatment of refractory schizophrenia.




Recent Advances in Neuropsychopharmacology


Book Description

Recent Advances In Neuropsychopharmacology contains selected papers from the 12th Congress of the Collegium Internationale Neuro-Psychopharmacologicum held in Gõteborg, Sweden, 22-26 June 1980. The 47 papers in the volume are organized into six parts. The papers in Part I deal with the subject of psychostimulants in psychiatric research. Topics covered include the effect of chronic d-amphetamine and chronic apomorphine treatment on non-human primate social and solitary behavior; and the behavioral effects of dopamine agonists. Part II assesses the prescription of psychotropic drugs by general ...







Fifty Years of LSD: Current Status and Perspectives of Hallucinogens


Book Description

This volume is the proceedings of the Symposium of the Swiss Academy of Medical Sciences held in Lugano-Agno in Switzerland in September 1993. It includes chapters in pharmacological, psychopathological and clinical aspects of LSD and hallucinogenic drug use in medicine, in addition to a personal historical account of the discovery of LSD by Professor Albert Hofmann, as well as social and cultural aspects of LSD.




Drug Discovery and Development, Third Edition


Book Description

Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of efficacy and safety of drug candidates through preclinical testing. This book also greatly expands the focus on the clinical pharmacology, regulatory, and business aspects of bringing new drugs to the market and offers coverage of essential topics for companies involved in drug development. Historical perspectives and predicted trends are also provided. Features: Highlights emerging scientific fields relevant to drug discovery such as the microbiome, nanotechnology, and cancer immunotherapy; and novel research tools such as CRISPR and DNA-encoded libraries Case study detailing the discovery of the anti-cancer drug, lorlatinib Venture capitalist commentary on trends and best practices in drug discovery and development Comprehensive review of regulations and their impact on drug development, highlighting special populations, orphan drugs, and pharmaceutical compounding Multidiscipline functioning of an Academic Research Enterprise, plus a chapter on Ethical Concerns in Research Contributions by 70+ experts from industry and academia specialists who developed and are practitioners of the science and business




The Treatment of Bipolar Disorder


Book Description

Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehensive guide to the integrative management of bipolar disorder. This resource contains 31 chapters on the various management choices available, from both established and novel treatment areas, such as psychoeducation, psychotherapeutic interventions, neuromodulatory approaches and novel therapeutic targets. The complexity and diversity of the management choices available makes this a continually evolving field and necessitates forward thinking. By both discussing the current management of bipolar disorder, and the future developments available, this resource provides all clinicians working with patients with bipolar disorder an up-to-date and reflective guide to its management and what the future holds.







Frontiers in Psychiatry


Book Description

This book reviews key recent advances and new frontiers within psychiatric research and clinical practice. These advances either represent or are enabling paradigm shifts in the discipline and are influencing how we observe, derive and test hypotheses, and intervene. Progress in information technology is allowing the collection of scattered, fragmented data and the discovery of hidden meanings from stored data, and the impacts on psychiatry are fully explored. Detailed attention is also paid to the applications of artificial intelligence, machine learning, and data science technology in psychiatry and to their role in the development of new hypotheses, which in turn promise to lead to new discoveries and treatments. Emerging research methods for precision medicine are discussed, as are a variety of novel theoretical frameworks for research, such as theoretical psychiatry, the developmental approach to the definition of psychopathology, and the theory of constructed emotion. The concluding section considers novel interventions and treatment avenues, including psychobiotics, the use of neuromodulation to augment cognitive control of emotion, and the role of the telomere-telomerase system in psychopharmacological interventions.




Emerging Cognitive Neuroscience and Related Technologies


Book Description

Emerging Cognitive Neuroscience and Related Technologies, from the National Research Council, identifies and explores several specific research areas that have implications for U.S. national security, and should therefore be monitored consistently by the intelligence community. These areas include: neurophysiological advances in detecting and measuring indicators of psychological states and intentions of individuals the development of drugs or technologies that can alter human physical or cognitive abilities advances in real-time brain imaging breakthroughs in high-performance computing and neuronal modeling that could allow researchers to develop systems which mimic functions of the human brain, particularly the ability to organize disparate forms of data. As these fields continue to grow, it will be imperative that the intelligence community be able to identify scientific advances relevant to national security when they occur. To do so will require adequate funding, intelligence analysts with advanced training in science and technology, and increased collaboration with the scientific community, particularly academia. A key tool for the intelligence community, this book will also be a useful resource for the health industry, the military, and others with a vested interest in technologies such as brain imaging and cognitive or physical enhancers.