Recent Advances in the Analysis of Marine Toxins


Book Description

Recent Advances in the Analysis of Marine Toxins, Volume 78, the newest release in the Comprehensive Analytical Chemistry series, presents chapters from the best authors in the field, making it an essential resource. Updated sections in this new volume include topics such as The importance of toxin detection and quantification: environmental issues, public health, food safety, animal health, bioterrorism, bioactive compounds, medical approach, an LC-MS/MS analysis of marine toxins, Animal bioassays: identification of toxins and mechanism of action, Receptor binding assays for the analysis of marine toxins, Immunoassays and optical biosensors (visual, SPR, fluorescence) for marine toxins, and Electrochemical biosensors for marine toxins. Chapters in this ongoing series contain practical and useful information, describing real advantages and limitations. Experts in this field contribute based on their research and personal point-of-view. - Contains contributions from the best authors in the field - Provides an essential resource for marine monitoring managers and scientific community




Emerging Marine Biotoxins


Book Description

The emergence of marine and freshwater toxins in geographical areas where they have never been reported before is a concern due to the considerable impact on (sea)food contamination, and consequently, on public health. Several groups of marine biotoxins, in particular tetrodotoxins, ciguatoxins, and palytoxins, are included among the relevant marine biotoxins that have recently emerged in several coastal areas. A similar situation has been observed in freshwater, where cyanobacterial toxins, such as microcystins, could end up in unexpected areas such as the estuaries where shellfish are cultivated. Climate change and the increased availability of nutrients have been considered as the key factors in the expansion of all of these toxins into new areas; however, this could also be due to more intense biological invasions, more sensitive analytical methods, or perhaps even an increased scientific interest in these natural contaminations. The incidences of human intoxications due to the consumption of seafood contaminated with these toxins have made their study an important task to accomplish in order to protect human health. This Special Issue has a focus on a wide variety of emerging biotoxin classes and techniques to identify and quantify them.




Marine Biotoxins


Book Description

This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.




Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems for harmful algal blooms


Book Description

Globally, there are 3 400 to 4 000 described species of marine microalgae but only 1 to 2 percent are considered to be harmful. Harmful algal blooms (HABs) have significant impacts on food safety and security through contamination or mass mortalities of aquatic organisms. The impacts and mass mortalities of marine species caused by harmful algae are not new and have been recorded for decades. However, there is growing concern that these events will increase due to accelerating global warming, climate change and anthropogenic activities. Indeed, if not properly controlled, aquatic products contaminated with HAB biotoxins are responsible for potentially deadly foodborne diseases and when rapidly growing, HAB consequences include reduced dissolved oxygen in the ocean, dead zones, and mass mortalities of aquatic organisms. Improving HAB forecasting is an opportunity to develop early warning systems for HAB events such as food contamination, mass mortalities, or foodborne diseases. Surveillance systems have been developed to monitor HABs in many countries; however, the lead-time or the type of data (i.e. identification at the species-level, determination of toxicity) may not be sufficient to take effective action for food safety management measures or other reasons, such as transfer of aquaculture products to other areas. Having early warning systems could help mitigate the impact of HABs and reduce the occurrence of HAB events. The Joint FAO-IOC-IAEA technical guidance for the implementation of early warning systems (EWS) for HABs will guide competent authorities and relevant institutions involved in consumer protection or environmental monitoring to implement early warning systems for HABs present in their areas (marine and brackish waters), specifically those affecting food safety or food security (benthic HABs, fish-killing HABs, pelagic toxic HABs, and cyanobacteria HABs). The guidance provides a roadmap for stakeholders on how to improve or implement an EWS for HABs and biotoxins, where appropriate. It is important to note that not all countries and institutions can implement the same level of EWS for HABs, and this guidance is intended mainly for those who seek to broaden existing early warning systems, or who are just beginning to consider putting a system in place.




Marine Neurotoxins


Book Description

Marine Neurotoxins, Volume Five provides comprehensive information on marine toxins present in the human food chain and the affecting targets relevant for the functioning of the brain and our nervous system, covering all the information available on their action on the physiology of neurons and glial cells, both "in vivo" or "in vitro." New sections in this release include Guanidinium Toxins: Evolution, Mode of Action and Chemical Ecology, Amnesic: Domoic Acid, Neurotoxic: Ciguatoxin and Brevetoxin, Neurotoxic: Cyclic Imines, Potentially Neurotoxic: Okadaic acid and analogues, Potentially Neurotoxic: Palytoxin, and Methods for assessing the presence of marine neurotoxins. - Focuses on the human nervous system and the effects marine toxins have on its function - Provides the latest information on established and potential neurotoxins - Includes updates on food related toxins




Biosensors for the Marine Environment


Book Description

This book is devoted to the exploration of innovative sensing technologies for marine applications. The book focuses on various novel biosensor designs from nano-biosensors to molecularly imprinted polymers offering a broad perspective for marine biosensors development to deployment challenges. The book aims to target researchers in the area of marine monitoring, sensor developments and deployment of devices in the marine environment.




Marine and Freshwater Toxins


Book Description

In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.







Magnetic Nanoparticles


Book Description

The present book covers all research areas related to magnetic nanoparticles, magnetic nanorods, and other magnetic nanospecies, their preparation, characterization, and various applications, specifically emphasizing biomedical applications. The chapters written by the leading experts cover different subareas of the science and technology related to various magnetic nanospecies—providing broad coverage of this multifaceted area and its applications. The different topics addressed in this book will be of great interest to the interdisciplinary community active in the area of nanoscience and nanotechnology. It is hoped that this collection and its various chapters will be important and beneficial for researchers and students working in various areas related to bionanotechnology, materials science, biosensor applications, medicine, and many others. Furthermore, this book is aimed at attracting young scientists and introducing them to this field, in addition to providing newcomers with an enormous collection of literature references.