Recent Translational Research in HIV/AIDS


Book Description

The collective efforts of HIV/AIDS research scientists from over 16 countries in the world are included in the book. This 27-chapter Open Access book well covers HIV/AIDS translational researches on pathogenesis, diagnosis, treatment, prevention, and also those beyond conventional fields. These are by no means inclusive, but they do offer a good foundation for the development of clinical patient care. The translational model forms the basis for progressing HIV/AIDS clinical research. When linked to the care of the patients, translational researches should result in a direct benefit for HIV/AIDS patients.




Disease Control Priorities, Third Edition (Volume 6)


Book Description

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.




The Role of NIH in Drug Development Innovation and Its Impact on Patient Access


Book Description

To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.




Oxford Textbook of Global Public Health


Book Description

Sixth edition of the hugely successful, internationally recognised textbook on global public health and epidemiology, with 3 volumes comprehensively covering the scope, methods, and practice of the discipline







The Comprehensive Cancer Center


Book Description

This open access book provides a valuable resource for hospitals, institutions, and health authorities worldwide in their plans to set up and develop comprehensive cancer care centers. The development and implementation of a comprehensive cancer program allows for a systematic approach to evidence-based strategies of prevention, early detection, diagnosis, treatment, and palliation. Comprehensive cancer programs also provide a nexus for the running of clinical trials and implementation of novel cancer therapies with the overall aim of optimizing comprehensive and holistic care of cancer patients and providing them with the best opportunity to improve quality of life and overall survival. This book's self-contained chapter format aims to reinforce the critical importance of comprehensive cancer care centers while providing a practical guide for the essential components needed to achieve them, such as operational considerations, guidelines for best clinical inpatient and outpatient care, and research and quality management structures. Intended to be wide-ranging and applicable at a global level for both high and low income countries, this book is also instructive for regions with limited resources. The Comprehensive Cancer Center: Development, Integration, and Implementation is an essential resource for oncology physicians including hematologists, medical oncologists, radiation oncologists, surgical oncologists, and oncology nurses as well as hospitals, health departments, university authorities, governments and legislators.




Pediatric Solid Organ Transplantation


Book Description

Pediatric Solid Organ Transplantation is acomprehensive and succinct text on all aspects of pediatric solidorgan transplantation. It provides a ready source of reference, toboth the basic science and organ specific surgical technique andafter care. This second edition has been extensively updated inlight of recent developments in this rapidly advancing area. The only textbook devoted to the field of pediatrictransplantation A definitive reference for all those interested in improvingthe care and quality of life of children undergoing solid organtransplantation Section on immunosuppression has been expanded by four chaptersto include sections on; - mechanisms of action - therapies for the sensitized patient - post-transplant lymphoproliferative disorders - organ toxicities of immunosuppressive therapy A new section has been added on the many topics related toquality of life that effect survivors of pediatrictransplantation International editorial and contributor team represents a widegeographical range and contains both recognized leaders andemerging experts Whether you are an established sub-specialist in pediatrictransplantation, a transplant surgeon, or a pediatric specialist ina related area, this book will answer all your questions about careof the pediatric patient before, during, and aftertransplantation.




Cures Vs. Profits: Successes In Translational Research


Book Description

Did you ever wonder whether doctors want cures, or just treatments?Did you know ... This book reviews recent key, hard-won successes and findings from recent biomedical research. Written by one of the most ardent defenders of the public trust in science, it provides an accessible, detailed look at successes in translational biomedical and clinical research. The author provides an optimistic, forward-looking view for the possibility of change for the public good, cutting through the controversy and gets to very core of each topic. The public can be optimistic about the future of medicine, but only if they learn the facts of these advances, and learn what their doctors should be expected to know.Highly referenced, and filled with interviews from experts and people directly involved in the research behind the new facts in each chapter, this book is a rich source of information on advances in biomedicine that you will want to share with your family & friends.







Principles of Translational Science in Medicine


Book Description

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. - Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine - Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology - Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization